Last updated September 2, 2026
Key finding
Mealtime WP supplementation reduced the prevalence of daily hyperglycemia by 8% ± 19% (30% ± 25% vs 38% ± 28%, p<0.05).
A study investigated the effects of a premeal whey protein shot on daily hyperglycemia in individuals with type 2 diabetes, finding significant reductions in hyperglycemia prevalence.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Extended (5–20+ y)
Risk of bias
Some Concerns
Save research, organize studies, and quickly find important evidence again.
Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
A study investigated the effects of a premeal whey protein shot on daily hyperglycemia in individuals with type 2 diabetes, finding significant reductions in hyperglycemia prevalence.
These findings are clinically significant as they suggest that incorporating a whey protein shot before meals could be an effective strategy for individuals with type 2 diabetes to manage their blood glucose levels. By reducing daily hyperglycemia and increasing euglycemia, this dietary intervention may help improve overall diabetes management and reduce the risk of complications associated with poor glycemic control.
Limited sample size may affect generalizability. Short duration of the study may not capture long-term effects. Unmeasured confounders could influence results.
Published in
Publication details and source links for this paper.
Kieran S, Guy ST, Lise HB, et al. Consuming a novel premeal whey protein shot reduces daily hyperglycemia in people with type 2 diabetes. BMJ Open Diabetes Research & Care. 2022;10(3):e002820. doi:10.1136/bmjdrc-2022-002820
Whey protein shot reduced daily hyperglycemia prevalence by 8% (p<0.05).
Increased time spent in euglycemia by 9% (~2 hours/day, p<0.05).
Mean 24-hour blood glucose was 0.6 mmol/L lower with whey protein (p<0.05).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Nutrient-depleted placebo beverage, Whey protein and Increase in time spent in euglycemia, Prevalence of daily hyperglycemia, Blood glucose.
This study contributes evidence to
Primary intervention
Nutrient-depleted placebo beverage
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
5
Evidence pairs
886
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Save studies and evidence pages, organize your personal Evidence Tracker, and keep the research you care about in one place.
Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Nutrient-depleted placebo beverage → Increase in time spent in euglycemia
Nutrient-depleted placebo beverage → Increase in time spent in euglycemia
Nutrient-depleted placebo beverage → Prevalence of daily hyperglycemia
Nutrient-depleted placebo beverage → Prevalence of daily hyperglycemia
Whey protein → Increase in time spent in euglycemia
Whey protein → Increase in time spent in euglycemia
Whey protein → Prevalence of daily hyperglycemia
Whey protein → Prevalence of daily hyperglycemia
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Nutrient-depleted placebo beverage and Prevalence of daily hyperglycemia, Nutrient-depleted placebo beverage and Increase in time spent in euglycemia.
This study contributes to the evidence on the following intervention-outcome relationships.
Curated evidence collections and hubs this study is part of.
All studies measuring Increase in time spent in euglycemia
Measures Increase in time spent in euglycemia as a key outcome.
All studies on Nutrient-depleted placebo beverage
Contributes to Nutrient-depleted placebo beverage evidence base.
All studies measuring Prevalence of daily hyperglycemia
Measures Prevalence of daily hyperglycemia as a key outcome.
Jump to pre-filtered views in Evidence Explorer.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Whey protein appears to improve blood glucose.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Blood glucose
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Whey protein appears to improve increase in time spent in euglycemia.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Increase in time spent in euglycemia
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Whey protein appears to improve prevalence of daily hyperglycemia.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Prevalence of daily hyperglycemia
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Nutrient-depleted placebo beverage for increase in time spent in euglycemia.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Increase in time spent in euglycemia
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Follow the topics this study contributes to.
Open broader Evidence Explorer views for this relationship.
Read related research summaries.
Focused on evidence, not advertising.
Your data is always protected.
New studies added every day.
