Last updated July 18, 2026
Key finding
There was no evidence of a difference in maternal weight change to 36 weeks between groups (intervention effect -0.20 (95% confidence interval -1.01, 0.61); P > 0.1)
This study investigated the effects of a reduced-energy diet during pregnancy on maternal glycaemia in women with gestational diabetes, finding no significant differences in maternal weight change or offspring birth weight between diet groups.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
High Risk
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of a reduced-energy diet during pregnancy on maternal glycaemia in women with gestational diabetes, finding no significant differences in maternal weight change or offspring birth weight between diet groups.
Understanding the impact of dietary interventions during pregnancy is crucial for managing gestational diabetes. This study suggests that a reduced-energy diet may not provide additional benefits in terms of maternal weight management or offspring birth weight, which can inform dietary guidelines and clinical practices for pregnant women with this condition.
Limited sample size may affect generalizability. Potential unmeasured confounders could influence outcomes. Short follow-up period may not capture long-term effects.
Published in
Publication details and source links for this paper.
Laura CK, Danielle J, Nooria A, et al. Reduced-energy diet in pregnancy improves maternal glycaemia in women with gestational diabetes. Nature Medicine. 2025;31(2):514-523. doi:10.1038/s41591-024-03356-1
No significant difference in maternal weight change to 36 weeks (intervention effect -0.20; P > 0.1)
No significant difference in offspring standardized birth weight (intervention effect 0.005; P > 0.1)
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Calorie restriction and Gestational weight gain, Offspring standardized birth weight.
This study contributes evidence to
Primary intervention
Calorie restriction
Primary outcomes
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
0
Related topics
2
Evidence pairs
0
Related studies
Core evidence
The primary outcomes reported in this study.
Calorie restriction → Gestational weight gain
Calorie restriction → Gestational weight gain
Calorie restriction → Offspring standardized birth weight
Calorie restriction → Offspring standardized birth weight
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Calorie restriction and Offspring standardized birth weight, Calorie restriction and Body Weight.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
All studies on Calorie restriction
Contributes to Calorie restriction evidence base.
All studies measuring Offspring standardized birth weight
Measures Offspring standardized birth weight as a key outcome.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Current evidence does not show a clear benefit of Calorie restriction for Gestational weight gain.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Gestational weight gain
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Calorie restriction for Offspring standardized birth weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Offspring standardized birth weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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