Research Summary
Analyzed using Evidence Intelligence™

Roux-en-Y gastric bypass shows better long-term outcomes than sleeve gastrectomy

Last updated July 18, 2026

Key finding

Mean HADS anxiety score for SG decreased by 1.59 units over 10-years (p = 0.027).

This study compared long-term outcomes of laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass in patients with type 2 diabetes and obesity, revealing significant differences in anxiety and physical health scores.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Extended (5–20+ y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study compared long-term outcomes of laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass in patients with type 2 diabetes and obesity, revealing significant differences in anxiety and physical health scores.

Clinical relevance

Understanding the long-term outcomes of these surgical interventions is crucial for clinicians and patients when considering weight loss surgery options. The findings suggest that while both procedures can reduce anxiety, Roux-en-Y gastric bypass may offer more significant benefits in physical health and overall well-being for patients with type 2 diabetes and obesity.

Keep in mind

Limited generalizability due to specific population characteristics. Potential unmeasured confounders affecting outcomes. Short follow-up duration may not capture all long-term effects.

Published in

Journal Reference

Publication details and source links for this paper.

Preekesh SP, Megan G, Anamitra N, et al. Long-term outcomes of laparoscopic sleeve gastrectomy versus Roux-en-Y gastric bypass in patients with type 2 diabetes and obesity. Obesity Surgery. 2026;36(5):2317-2327. doi:10.1007/s11695-026-08623-3

Main Effects

SG group showed a decrease in HADS anxiety score by 1.59 units (p = 0.027).

SR-RYGB group improved RAND-36 physical function scores by 19 points compared to 12 points for SG (p = 0.026).

SR-RYGB group improved RAND-36 general health scores by 17 points compared to 10 points for SG (p = 0.036).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Gastric bypass, Sleeve gastrectomy and Anxiety score, Improvements in RAND-36 General Health Score, Physical functioning, and 1 more.

Primary intervention

Gastric bypass

Primary outcomes

  • Anxiety score
  • Improvements in RAND-36 General Health Score
  • Physical functioning

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

8
Evidence pairs
8
Relationships
1
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 47

1

Related topics

8

Evidence pairs

6

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 8 evidence relationships
  • Linked to 1 direct semantic evidence topic

Topic contributions

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Bariatric Procedures and Mental Health

Related evidence

Evidence topic

Bariatric Procedures

Save evidence

Intervention

Bariatric Procedures

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Anxiety score

Gastric bypass → Anxiety score

Gastric bypass → Anxiety score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Improvements in RAND-36 General Health Score

Gastric bypass → Improvements in RAND-36 General Health Score

Gastric bypass → Improvements in RAND-36 General Health Score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Physical functioning

Gastric bypass → Physical functioning

Gastric bypass → Physical functioning

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Role limitation due to emotional problems score

Gastric bypass → Role limitation due to emotional problems score

Gastric bypass → Role limitation due to emotional problems score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Anxiety score

Sleeve gastrectomy → Anxiety score

Sleeve gastrectomy → Anxiety score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Improvements in RAND-36 General Health Score

Sleeve gastrectomy → Improvements in RAND-36 General Health Score

Sleeve gastrectomy → Improvements in RAND-36 General Health Score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Physical functioning

Sleeve gastrectomy → Physical functioning

Sleeve gastrectomy → Physical functioning

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Role limitation due to emotional problems score

Sleeve gastrectomy → Role limitation due to emotional problems score

Sleeve gastrectomy → Role limitation due to emotional problems score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Anxiety decreased by 1.59 units for SG patients (p = 0.027).
  • SR-RYGB improved physical function by 19 points compared to SG's 12 points (p = 0.026).
  • General health scores improved by 17 points for SR-RYGB versus 10 points for SG (p = 0.036).
who this applies

Who this applies to

  • Adults with type 2 diabetes and obesity considering weight loss surgery.
  • Patients seeking long-term outcomes of bariatric procedures.
keep in mind

Keep in Mind

  • Results may not apply to populations outside the study's demographics.
  • Long-term follow-up is essential for comprehensive outcome assessment.
  • Differences in emotional well-being need further exploration.
between the lines

Between the Lines

  • Limited generalizability due to specific population characteristics.
  • Potential unmeasured confounders affecting outcomes.
  • Short follow-up duration may not capture all long-term effects.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Bariatric Procedures and Mental Health, Bariatric Procedures and Physical functioning.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Bariatric Procedures improve mental health?

Emerging Evidence

Current evidence does not show a clear benefit of Bariatric Procedures for Mental Health.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Anxiety score

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Gastric bypass improve improvements in rand-36 general health score?

Emerging Evidence

Gastric bypass appears to improve Improvements in RAND-36 General Health Score.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Improvements in RAND-36 General Health Score

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Gastric bypass improve physical functioning?

Emerging Evidence

Gastric bypass appears to improve Physical functioning.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Physical functioning

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Sleeve gastrectomy improve improvements in rand-36 general health score?

Emerging Evidence

Sleeve gastrectomy appears to improve Improvements in RAND-36 General Health Score.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Improvements in RAND-36 General Health Score

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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