Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 67
- Slightly Positive
- ConsistencyScore™
- 67
- generally_consistent
Supporting studies: Based on 3 studies
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Analyzed using Evidence Intelligence™
RT-CGM Enhances Glycemic Control in Prediabetes
Last updated September 9, 2026
Key finding
The RT-CGM group demonstrated significantly greater improvements in HbA1c compared to controls at both 1-year (p=0.007) and 2-year (p=0.033) follow-ups.
This study evaluated the impact of real-time continuous glucose monitoring (RT-CGM) on glycemic control in prediabetes. The RT-CGM group showed significant improvements in HbA1c compared to controls.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the impact of real-time continuous glucose monitoring (RT-CGM) on glycemic control in prediabetes. The RT-CGM group showed significant improvements in HbA1c compared to controls.
Clinical relevance
Improving glycemic control in prediabetes is crucial for preventing the progression to type 2 diabetes. This study highlights the potential of RT-CGM as a valuable tool in diabetes health education, suggesting that integrating technology into lifestyle interventions can lead to better health outcomes for at-risk populations.
Keep in mind
The study may have limited generalizability due to specific inclusion criteria. Potential confounding variables were not fully controlled. The sample size and demographic diversity were not specified.
Published in
Journal Reference
Publication details and source links for this paper.
Yuqi M, Sisi D, Wei X, Minfang W, Yeran J. Incorporating Real-Time Continuous Glucose Monitoring into Diabetes Health Education Improves Glycemic Control in Prediabetes. Diabetes, Metabolic Syndrome and Obesity. 2025;18:1939-1948. doi:10.2147/DMSO.S511187
Main Effects
The RT-CGM group demonstrated a significant reduction in HbA1c by -0.49% at 1-year follow-up (p=0.007).
The RT-CGM group also showed a significant reduction in HbA1c at 2-year follow-up (p=0.033).
No significant differences were observed in fasting plasma glucose, BMI, lipid profiles, or uric acid levels between groups.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Continuous glucose monitoring and BMI, Fasting Plasma Glucose (FPG), HbA1c, and 2 more.
This study contributes evidence to
Primary intervention
Continuous glucose monitoring
Primary outcomes
- BMI
- Fasting Plasma Glucose (FPG)
- HbA1c
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
5
Evidence pairs
5
Relationships
5
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 72
5
Related topics
5
Evidence pairs
1920
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 5 evidence relationships
- Includes primary outcome data
- Linked to 4 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence relationship
Insulin Delivery Systems and HbA1c
Related evidence
Evidence relationship
Insulin Delivery Systems and Fasting Glucose
Save evidence
Evidence relationship
Insulin Delivery Systems and Body Mass Index
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Fasting Plasma Glucose (FPG)
Continuous glucose monitoring → Fasting Plasma Glucose (FPG)
Continuous glucose monitoring → Fasting Plasma Glucose (FPG)
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 67
- Slightly Positive
- ConsistencyScore™
- 67
- generally_consistent
Supporting studies: Based on 3 studies
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- 85
- Strong
- ImpactScore™
- 83
- Positive
- ConsistencyScore™
- 83
- consistent
Supporting studies: Based on 12 studies
Add to Evidence Trackerlipid profiles
Continuous glucose monitoring → lipid profiles
Continuous glucose monitoring → lipid profiles
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
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Evidence Suggest
- RT-CGM led to a significant HbA1c reduction of -0.49% at 1 year.
- No significant changes were observed in fasting plasma glucose levels.
- Control group showed no significant improvement in HbA1c.
Who this applies to
- Adults diagnosed with prediabetes.
- Individuals engaged in diabetes health education programs.
Keep in Mind
- Results may not apply to populations outside the study's demographic.
- The long-term effects of RT-CGM on diabetes prevention need further investigation.
- The study did not measure all potential confounding factors affecting outcomes.
Between the Lines
- The study may have limited generalizability due to specific inclusion criteria.
- Potential confounding variables were not fully controlled.
- The sample size and demographic diversity were not specified.
Evidence Library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Insulin Delivery Systems and HbA1c, Insulin Delivery Systems and Body Mass Index.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Devices & Technology
Insulin Delivery Systems → HbA1c
Devices & Technology
Evidence Intelligence™
- EvidenceScore™
- 85
- Strong
- ImpactScore™
- 83
- Positive
- ConsistencyScore™
- 83
- consistent
Supporting studies: Based on 12 studies
View evidenceDevices & Technology
Insulin Delivery Systems → Body Mass Index
Devices & Technology
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 67
- Slightly Positive
- ConsistencyScore™
- 67
- generally_consistent
Supporting studies: Based on 3 studies
View evidenceDevices & Technology
Insulin Delivery Systems → lipid profiles
Devices & Technology
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
HbA1c Evidence Hub
All studies measuring HbA1c
12 studies
outcome_hubMeasures HbA1c as a key outcome.
Insulin Delivery Systems Evidence Hub
All studies on Insulin Delivery Systems
12 studies
intervention_hubContributes to Insulin Delivery Systems evidence base.
Body Mass Index Evidence Hub
All studies measuring Body Mass Index
3 studies
outcome_hubMeasures Body Mass Index as a key outcome.
lipid profiles Evidence Hub
All studies measuring lipid profiles
1 studies
outcome_hubMeasures lipid profiles as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Continuous glucose monitoring and HbA1c
Intervention: Continuous glucose monitoringOutcome: HbA1c
12 results
All studies on Continuous glucose monitoring and BMI
Intervention: Continuous glucose monitoringOutcome: BMI
3 results
All studies on Continuous glucose monitoring
Intervention: Continuous glucose monitoring
12 results
All studies measuring HbA1c
Outcome: HbA1c
12 results
All studies measuring BMI
Outcome: BMI
3 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Insulin Delivery Systems lower HbA1c?
Strong Evidence
Insulin Delivery Systems appears to lower HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 85.5 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 20 supporting studies with consistent results and a positive effect signal.
Does Insulin Delivery Systems improve fasting glucose?
Strong Evidence
Insulin Delivery Systems may improve fasting glucose.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Fasting Plasma Glucose (FPG)
EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on 9 supporting studies with consistent results and a positive effect signal.
Does Insulin Delivery Systems affect body mass index?
Strong Evidence
Insulin Delivery Systems may affect body mass index.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
BMI
EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Does Insulin Delivery Systems improve uric acid levels?
Emerging Evidence
Current evidence does not show a clear benefit of Insulin Delivery Systems for uric acid levels.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Uric Acid
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
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