Research Summary
Analyzed using Evidence Intelligence™

Telemedicine improves glycemic control in type 2 diabetes patients

Key finding

The intervention group showed a significant reduction in HbA1c to 6.7% (±0.21), compared to 7.0% (±0.15) in the control group (p = 0.035).

This study evaluated the effectiveness of a telemedicine intervention for glycemic control in patients with Type 2 diabetes and found significant improvements in several key outcomes.

Evidence strength

Moderate confidence

Study type

RCTs

Follow-up

Long-Term (1–5 y)

Some Concerns bias
Last updated July 8, 2026

Quick read

Study at a glance

The essential study design details in one scan.

Population

Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes

Intervention

Telemedicine intervention with weekly interactive voice calls

Study type

RCTs

Follow-up

Long-Term (1–5 y)

Primary outcome

HbA1c

Comparator

Standard care with clinic visits every three months

Plain-language summary

What this paper says

A plain-language read of the study's main message and where it applies.

Study focus

This study evaluated the effectiveness of a telemedicine intervention for glycemic control in patients with Type 2 diabetes and found significant improvements in several key outcomes.

Clinical relevance

Improving glycemic control is crucial for preventing complications in patients with Type 2 diabetes. This study demonstrates that telemedicine can be an effective tool for enhancing patient engagement and adherence to treatment, potentially leading to better health outcomes and reduced healthcare costs.

Keep in mind

The study's sample size may limit the generalizability of the findings. Potential biases in self-reported medication compliance could affect results. The long-term sustainability of the intervention's effects was not assessed.

Published in

Journal Reference

Publication details and source links for this paper.

Alexander M, John RA, Vinoth GCD, Pradakshna P, Jennifer BJ, Vijayalakshmi S. Telemedicine Interventions for Glycemic Control in Patients with Type 2 Diabetes: A Randomized Controlled Trial. Cureus. 2025;17(9):e91996. doi:10.7759/cureus.91996

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Main Effects

HbA1c levels decreased by 0.6% in the intervention group (p = 0.035).

Fasting plasma glucose improved by 21 mg/dL in the intervention group (p = 0.046).

Postprandial blood glucose levels decreased by 21 mg/dL in the intervention group (p = 0.032).

Insulin resistance (HOMA-IR) was reduced by 1.2 units in the intervention group (p = 0.04).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to mHealth intervention with personal feedback and Fasting Plasma Glucose (FPG), Glucose iAUC (OGTT), HbA1c, and 3 more.

Primary intervention

mHealth intervention with personal feedback

Primary outcomes

  • Fasting Plasma Glucose (FPG)
  • Glucose iAUC (OGTT)
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

6
Evidence pairs
6
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

3

Related topics

6

Evidence pairs

315

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 6 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Core evidence

Study findings

The primary outcomes reported in this study.

StrongDecrease

Fasting Plasma Glucose (FPG)

mHealth intervention with personal feedback → Fasting Plasma Glucose (FPG)

mHealth intervention with personal feedback → Fasting Plasma Glucose (FPG)

Evidence profile

StrongDecreaseGlycemic Control
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StrongDecrease

Glucose iAUC (OGTT)

mHealth intervention with personal feedback → Glucose iAUC (OGTT)

mHealth intervention with personal feedback → Glucose iAUC (OGTT)

Evidence profile

StrongDecreaseGlycemic Control
Unlock full evidence details
StrongDecrease

HbA1c

mHealth intervention with personal feedback → HbA1c

mHealth intervention with personal feedback → HbA1c

Evidence profile

StrongDecreaseGlycemic Control
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StrongDecrease

Insulin resistance

mHealth intervention with personal feedback → Insulin resistance

mHealth intervention with personal feedback → Insulin resistance

Evidence profile

StrongDecreaseMetabolic Health
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StrongIncrease

Lifestyle behaviors

mHealth intervention with personal feedback → Lifestyle behaviors

mHealth intervention with personal feedback → Lifestyle behaviors

Evidence profile

StrongIncreaseAdherence & Engagement
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StrongIncrease

Treatment adherence

mHealth intervention with personal feedback → Treatment adherence

mHealth intervention with personal feedback → Treatment adherence

Evidence profile

StrongIncreaseAdherence & Engagement
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evidence suggest

Evidence Suggest

  • HbA1c decreased significantly to 6.7% in the intervention group.
  • Fasting plasma glucose improved to 113 mg/dL with telemedicine.
  • Postprandial glucose levels were significantly lower at 142 mg/dL.
who this applies

Who this applies to

  • Adults diagnosed with Type 2 diabetes.
  • Patients seeking alternative management strategies for diabetes.
keep in mind

Keep in Mind

  • Results may not apply to all demographics or settings.
  • The study did not explore the long-term effects of the intervention.
  • Further research is needed to confirm findings in larger populations.
between the lines

Between the Lines

  • The study's sample size may limit the generalizability of the findings.
  • Potential biases in self-reported medication compliance could affect results.
  • The long-term sustainability of the intervention's effects was not assessed.

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on mHealth intervention with personal feedback and HbA1c, mHealth intervention with personal feedback and Fasting Glucose.

Related evidence relationships

Explore in Evidence Archive

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does mHealth intervention with personal feedback improve HbA1c?

Emerging Evidence

mHealth intervention with personal feedback appears to improve HbA1c.

ConsensusScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 56.5 | strong positive | ConsensusScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does mHealth intervention with personal feedback improve fasting plasma glucose (fpg)?

Emerging Evidence

mHealth intervention with personal feedback appears to improve Fasting Plasma Glucose (FPG).

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does mHealth intervention with personal feedback improve glucose iauc (ogtt)?

Emerging Evidence

mHealth intervention with personal feedback appears to improve Glucose iAUC (OGTT).

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Glucose iAUC (OGTT)

    EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does mHealth intervention with personal feedback improve insulin resistance?

Emerging Evidence

mHealth intervention with personal feedback appears to improve Insulin resistance.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Insulin resistance

    EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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