Last updated August 18, 2026
Key finding
UDCA treatment was associated with more negative left atrial strain during atrial contraction (p = 0.016).
UDCA treatment compared to placebo in women with gestational diabetes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
Save research, organize studies, and quickly find important evidence again.
Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
UDCA treatment compared to placebo in women with gestational diabetes.
This study evaluated UDCA treatment compared to placebo in women with gestational diabetes.
Limitations were not clearly described in the extracted text.
Published in
Publication details and source links for this paper.
Ana MCC, Jose EB, Christos C, et al. Effects of Ursodeoxycholic Acid on Maternal Cardiac Function in Gestational Diabetes Mellitus: A Randomized Controlled Trial. Journal of Clinical Medicine. 2026;15(2). doi:10.3390/jcm15020786
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Ursodeoxycholic acid and Left atrial contractile strain (LASct_AC), Left atrial reservoir strain (LASr_ED).
This study contributes evidence to
Primary intervention
Ursodeoxycholic acid
Primary outcomes
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
0
Related topics
2
Evidence pairs
0
Related studies
Core evidence
The primary outcomes reported in this study.
Ursodeoxycholic acid → Left atrial contractile strain (LASct_AC)
Ursodeoxycholic acid → Left atrial contractile strain (LASct_AC)
Ursodeoxycholic acid → Left atrial reservoir strain (LASr_ED)
Ursodeoxycholic acid → Left atrial reservoir strain (LASr_ED)
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Omega-3 Fatty Acid Supplements and Left atrial contractile strain (LASct_AC), Omega-3 Fatty Acid Supplements and Left atrial reservoir strain (LASr_ED).
This study contributes to the evidence on the following intervention-outcome relationships.
Curated evidence collections and hubs this study is part of.
All studies measuring Left atrial contractile strain (LASct_AC)
Measures Left atrial contractile strain (LASct_AC) as a key outcome.
All studies measuring Left atrial reservoir strain (LASr_ED)
Measures Left atrial reservoir strain (LASr_ED) as a key outcome.
All studies on Omega-3 Fatty Acid Supplements
Contributes to Omega-3 Fatty Acid Supplements evidence base.
Jump to pre-filtered views in Evidence Explorer.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Ursodeoxycholic acid appears to improve Left atrial reservoir strain (LASr_ED).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Left atrial reservoir strain (LASr_ED)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Ursodeoxycholic acid may worsen Left atrial contractile strain (LASct_AC) or be associated with harm.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Left atrial contractile strain (LASct_AC)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | moderate negative | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Open broader Evidence Explorer views for this relationship.
Focused on evidence, not advertising.
Your data is always protected.
New studies added every day.
