Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
Vitamin D supplementation may improve musculoskeletal pain in pregnant women
Last updated July 6, 2026
Key finding
There was a statistically significant difference in serum vitamin D level (P=0.016)
This study investigated the impact of vitamin D supplementation on fasting blood glucose levels in pregnant women with gestational diabetes, finding no significant effect on glucose levels.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the impact of vitamin D supplementation on fasting blood glucose levels in pregnant women with gestational diabetes, finding no significant effect on glucose levels.
Clinical relevance
Understanding the effects of vitamin D supplementation in pregnant women with gestational diabetes is crucial for developing effective management strategies. Although vitamin D improved serum levels, the lack of impact on fasting blood glucose suggests that additional interventions may be necessary to manage this condition effectively.
Keep in mind
Limited sample size may affect generalizability Short duration of supplementation could limit long-term effects Potential unmeasured confounders not accounted for
Published in
Journal Reference
Publication details and source links for this paper.
Zahra M, Sakineh M, Elnaz S, Shamsi A, Mojgan M. The effect of vitamin D supplementation on fasting blood glucose levels in pregnant women with gestational diabetes. BMC Endocrine Disorders. 2022;22:254. doi:10.1186/s12902-022-01159-4
Main Effects
No significant change in fasting blood glucose (P=0.850)
Significant increase in serum vitamin D levels (P=0.016)
Significant differences in knee pain (P=0.025) and ankle pain (P<0.001)
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Vitamin D supplementation and Ankle pain, Blood glucose, Depression score, and 7 more.
This study contributes evidence to
Primary intervention
Vitamin D supplementation
Primary outcomes
- Ankle pain
- Blood glucose
- Depression score
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
10
Evidence pairs
10
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
3
Related topics
10
Evidence pairs
1145
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 10 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
Insulin Resistance
matched_intervention_and_outcome
Related evidence
Evidence topic
Supplements and Nutraceuticals
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 67
- Slightly Positive
- ConsistencyScore™
- 67
- generally_consistent
Supporting studies: Based on 3 studies
Add to Evidence TrackerDepression score
Vitamin D supplementation → Depression score
Vitamin D supplementation → Depression score
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Supporting studies: Based on 2 studies
Add to Evidence TrackerFasting insulin levels
Vitamin D supplementation → Fasting insulin levels
Vitamin D supplementation → Fasting insulin levels
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 63
- Slightly Positive
- ConsistencyScore™
- 75
- consistent
Supporting studies: Based on 4 studies
Add to Evidence TrackerFrequency of abortion
Vitamin D supplementation → Frequency of abortion
Vitamin D supplementation → Frequency of abortion
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerGestational diabetes mellitus incidence
Vitamin D supplementation → Gestational diabetes mellitus incidence
Vitamin D supplementation → Gestational diabetes mellitus incidence
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerInsulin resistance
Vitamin D supplementation → Insulin resistance
Vitamin D supplementation → Insulin resistance
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 63
- Slightly Positive
- ConsistencyScore™
- 75
- consistent
Supporting studies: Based on 4 studies
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerSerum concentration of vitamin D
Vitamin D supplementation → Serum concentration of vitamin D
Vitamin D supplementation → Serum concentration of vitamin D
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Supporting studies: Based on 4 studies
Add to Evidence TrackerEvidence Library
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Evidence Suggest
- No change in fasting blood glucose levels (P=0.850)
- Significant increase in serum vitamin D levels (P=0.016)
- Significant reduction in knee and ankle pain
Who this applies to
- Pregnant women diagnosed with gestational diabetes
- Women in their second or third trimester of pregnancy
Keep in Mind
- Results may not apply to populations outside the study demographics
- The study did not assess long-term effects of vitamin D supplementation
- Findings should be interpreted with caution due to the lack of significant changes in key metabolic outcomes
Between the Lines
- Limited sample size may affect generalizability
- Short duration of supplementation could limit long-term effects
- Potential unmeasured confounders not accounted for
Evidence Library
Build your evidence library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Vitamin D supplementation and Insulin Resistance, Vitamin D supplementation and Insulin Resistance.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 63
- Slightly Positive
- ConsistencyScore™
- 75
- consistent
Supporting studies: Based on 4 studies
View evidenceSupplements
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 63
- Slightly Positive
- ConsistencyScore™
- 75
- consistent
Supporting studies: Based on 4 studies
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Vitamin D supplementation and Fasting insulin levels
Intervention: Vitamin D supplementationOutcome: Fasting insulin levels
4 results
All studies on Vitamin D supplementation and Insulin resistance
Intervention: Vitamin D supplementationOutcome: Insulin resistance
4 results
All studies on Vitamin D supplementation
Intervention: Vitamin D supplementation
4 results
All studies measuring Fasting insulin levels
Outcome: Fasting insulin levels
4 results
All studies measuring Insulin resistance
Outcome: Insulin resistance
4 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Vitamin D supplementation improve serum concentration of vitamin d?
Strong Evidence
Vitamin D supplementation appears to improve Serum concentration of vitamin D.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Serum concentration of vitamin D
EvidenceScore™ Strong | EvidenceScore™ 79.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does Vitamin D supplementation improve fasting insulin levels?
Strong Evidence
Vitamin D supplementation may improve Fasting insulin levels.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Fasting insulin levels
EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does Vitamin D supplementation improve insulin resistance?
Strong Evidence
Vitamin D supplementation may improve Insulin resistance.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Insulin resistance
EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does Vitamin D supplementation improve blood glucose?
Strong Evidence
Vitamin D supplementation may improve Blood glucose.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
Blood glucose
EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
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