Structured population data were available for 9 of 9 supporting studies. 3 studies described participants with type 2 diabetes. 7 studies described adult participants.

1 relevant study has unresolved authoritative design evidence and does not contribute to design-specific or RoB-specific claims.

1 supporting study does not have a displayable topic-matched quantitative effect.

Evidence uses heterogeneous comparison contexts: baseline_within_group, other, unknown_unresolved, usual_care.

4 supporting studies have high, serious, critical, unclear, or unavailable risk-of-bias information.

1 study contains conflicting p-value and significance fields; those significance claims are suppressed.

Core clinician-reference fields are available or not applicable.

Twelve group-based sessions and two individual counselling sessions over 12 months, delivered by trained community volunteers

Co-HELP community-based lifestyle intervention

Usual care

Authoritative quality diagnostic: invalid confidence interval.

Authoritative quality diagnostic: invalid or missing value.

Authoritative quality diagnostic: p value significance conflict.

Community lifestyle programme improves multiple diabetes risk factors in adults with prediabetes

6-h session at baseline followed by 3-h refresher sessions at 12 and 24 mo; 15-min telephone call every 3 mo

Let's Prevent Diabetes programme (intervention)

Standard care

Engagement in a prediabetes education programme is linked to lower type 2 diabetes risk

Not extracted from the authoritative source.

Clinician-reference record is usable with limitations in: arms, comparator.

Intensive lifestyle intervention improves diabetes remission in India

Not applicable to this study design or comparison.

Source evidence could not be resolved sufficiently for this field.

Clinician-reference record is usable with limitations in: design, risk_of_bias.

A comprehensive lifestyle intervention aimed at achieving diabetes remission in a patient with type 2 diabetes.

Intensive Lifestyle Intervention

This case involved a 64-year-old man with type 2 diabetes (T2D) who underwent radical nephrectomy for renal cell carcinoma. He consented to a 1-year intensive lifestyle intervention (ILI), including a vegan diet (to lower calorie intake, reduce uric acid, support renal health, and promote weight loss), intermittent fasting, regular exercise, psychological support, and medical management.

Authoritative quality diagnostic: source evidence unresolved.

Intensive lifestyle intervention may reverse diabetes in nephrectomy patients

Available source content was suppressed because validation identified a conflict.

Intensive lifestyle intervention aiming to increase physical activity, modify diet, and promote weight loss ≥5%. Based on Finnish DPS protocol with local adaptations across three European centres.

Intensive lifestyle intervention (EDIPS protocol)

Lifestyle advice control

Authoritative quality diagnostic: invalid or missing unit.

Intensive lifestyle programme cuts type 2 diabetes risk by 57% in European prediabetes trial

One individual and ten group sessions focused on lifestyle changes were provided followed by six telephone sessions and two motivational letters over a period of 10 months; free physical activity sessions were offered twice a week from week four

DE-PLAN lifestyle intervention programme

Lifestyle programme linked to lasting weight loss in some adults at high diabetes risk

Standard lifestyle education

Participants followed a 5:2 intermittent energy-restricted diet.

Diet Intervention Group

Participants were randomly assigned to one of three groups: a diet intervention group following a 5:2 intermittent energy-restricted diet.

Participants performed twice-weekly supervised low-volume high-intensity interval training combined with resistance exercise.

Exercise Intervention Group

Participants were randomly assigned to one of three groups: an exercise intervention group performing twice-weekly supervised low-volume high-intensity interval training combined with resistance exercise.

Control group receiving standard lifestyle education.

Participants were randomly assigned to one of three groups: a control group receiving standard lifestyle education.

Metabolomics score improves metabolic profiling in diabetes

One individual session (60-90 min), five group sessions (90 min each), and two telephone sessions (15-20 min). Only 10% attended all sessions, 53% attended one individual + at least one group, 34% attended none.

MAGDA-DPP lifestyle modification programme

Postnatal lifestyle programme prevents weight gain after gestational diabetes

Standard care diabetes education (DE)

Participants received a structured diabetes education programme via two one-to-one telephone calls with a registered dietitian and free membership of Weight Watchers for 6 months.

Tailored diabetes education and behavioural weight management programme (DEW)

Participants randomised to DEW (the ‘intervention’) received a structured diabetes education programme via two one-to-one telephone calls with a registered dietitian (provided by WW) and free membership of WW for 6 months.

Participants attended a 6 h diabetes education workshop delivered by trained healthcare professionals in local healthcare or community venues.

Participants allocated to DE (‘control’) attended a 6 h diabetes education workshop (DESMOND) delivered by two trained healthcare professionals in local healthcare or community venues in groups of up to ten participants.

Lifestyle intervention for prediabetes × Body weight

Available supporting studies