Exercise TherapyPrediabetes
Research Summary
Analyzed using Evidence Intelligence™

Resistance training may help reverse prediabetes and improve strength

Last updated June 15, 2026

Key finding

Strength increases were maintained through month 15 and represented improvements of 21% and 14% for chest and leg press.

This trial tested whether adults with prediabetes could start and maintain resistance training. After a supervised 3-month training phase, about one-third of participants were no longer prediabetic, and this was mostly maintained through 15 months. Extra social-cognitive support did not outperform lower-contact standard care.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

Randomized controlled trial

Follow-up

Long-Term (1–5 y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This trial tested whether adults with prediabetes could start and maintain resistance training. After a supervised 3-month training phase, about one-third of participants were no longer prediabetic, and this was mostly maintained through 15 months. Extra social-cognitive support did not outperform lower-contact standard care.

Clinical relevance

Prediabetes often progresses to type 2 diabetes, and many prevention programs rely on broad lifestyle changes that can be hard to maintain. This study suggests that a focused resistance training program may be a practical single-component strategy for some older adults with prediabetes. However, the trial did not include a no-exercise control group, so the benefit of resistance training alone should be interpreted cautiously.

Keep in mind

No no-exercise control group over the full 15-month trial Participants were mostly White, female, and college educated Maintenance adherence declined by month 15 Findings may not generalize to younger or more diverse populations

Main Effects

Normoglycemia status ↑ (34% after 3 months; 30% at 15 months)

Muscular strength ↑ (chest press 21%, leg press 14%)

Fasting plasma glucose → (no clear change reported)

Evidence network

How this study fits

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Evidence Context

This study contributes evidence to Behavioral counseling, Resistance training and Normoglycemia status, Treatment adherence, 2-hour plasma glucose, and 5 more.

Primary intervention

Behavioral counseling

Primary outcomes

  • Normoglycemia status
  • Treatment adherence
  • 2-hour plasma glucose

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

10
Evidence pairs
10
Relationships
8
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

8

Related topics

10

Evidence pairs

1095

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 10 evidence relationships
  • Includes primary outcome data
  • Linked to 8 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence relationship

Diabetes Self-Management Education and Support (DSMES) Programs and Treatment Adherence

Related evidence

Evidence topic

Prediabetes

Save evidence

Evidence topic

Diabetic Neuropathy

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Normoglycemia status

Behavioral counseling → Normoglycemia status

Behavioral counseling → Normoglycemia status

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
55
Slightly Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Treatment adherence

Behavioral counseling → Treatment adherence

Behavioral counseling → Treatment adherence

Evidence Intelligence™
EvidenceScore™
73
Moderate
ImpactScore™
55
Slightly Positive
ConsistencyScore™
67
generally_consistent
Supporting studies: Based on 3 studies
Add to Evidence Tracker

2-hour plasma glucose

Resistance training → 2-hour plasma glucose

Resistance training → 2-hour plasma glucose

Evidence Intelligence™
EvidenceScore™
75
Moderate
ImpactScore™
50
Neutral
ConsistencyScore™
35
mixed
Supporting studies: Based on 3 studies
Add to Evidence Tracker

Adverse events incidence

Resistance training → Adverse events incidence

Resistance training → Adverse events incidence

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
55
Slightly Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting blood sugar (FBS)

Resistance training → Fasting blood sugar (FBS)

Resistance training → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
68
Moderate
ImpactScore™
55
Slightly Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Insulin resistance

Resistance training → Insulin resistance

Resistance training → Insulin resistance

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
78
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Muscular strength

Resistance training → Muscular strength

Resistance training → Muscular strength

Evidence Intelligence™
EvidenceScore™
68
Moderate
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Normoglycemia status

Resistance training → Normoglycemia status

Resistance training → Normoglycemia status

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Treatment adherence

Resistance training → Treatment adherence

Resistance training → Treatment adherence

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
55
Slightly Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Waist circumference

Resistance training → Waist circumference

Resistance training → Waist circumference

Evidence Intelligence™
EvidenceScore™
68
Moderate
ImpactScore™
73
Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Evidence Library

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keep in mind

Keep in Mind

  • No no-exercise control group over the full 15-month trial Participants were mostly White, female, and college educated Maintenance adherence declined by month 15 Findings may not generalize to younger or more diverse populations
between the lines

Between the Lines

  • No no-exercise control group over the full 15-month trial Participants were mostly White, female, and college educated Maintenance adherence declined by month 15 Findings may not generalize to younger or more diverse populations

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Resistance training and Postprandial and OGTT Glucose, Diabetes Self-Management Education and Support (DSMES) Programs and Treatment Adherence.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Diabetes Self-Management Education and Support (DSMES) Programs improve treatment adherence?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Treatment Adherence.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Treatment adherence

    EvidenceScore™ Moderate | EvidenceScore™ 73.0 | weak positive | ConsistencyScore™ Generally Consistent | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Population details are unavailable.
8 supporting studiesUpdated: Jul 2026

Does Resistance training improve 2-hour plasma glucose?

Moderate Evidence

Current evidence does not show a clear benefit of Resistance training for 2-hour plasma glucose.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    2-hour plasma glucose

    EvidenceScore™ Moderate | EvidenceScore™ 75.0 | neutral | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Resistance training improve insulin resistance?

Moderate Evidence

Resistance training may improve Insulin resistance.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Insulin resistance

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Resistance training improve muscular strength?

Moderate Evidence

Resistance training appears to improve Muscular strength.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Muscular strength

    EvidenceScore™ Moderate | EvidenceScore™ 68.2 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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