Last updated September 2, 2026
Key finding
The CRHP group reported a 4% lower carbohydrate intake (p ≤ 0.05).
This study compared a carbohydrate-reduced high-protein diet to a conventional diabetes diet over six weeks, finding improved glycemic control with the former.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study compared a carbohydrate-reduced high-protein diet to a conventional diabetes diet over six weeks, finding improved glycemic control with the former.
This study highlights the potential benefits of a carbohydrate-reduced high-protein diet for individuals with diabetes. Improved dietary management can lead to better glycemic control, which is crucial for preventing complications associated with diabetes. Understanding the effectiveness of different dietary approaches can help clinicians tailor nutritional advice to optimize patient outcomes.
The study's sample size and population characteristics may limit generalizability. The duration of the study was only six weeks, which may not reflect long-term effects. Effectiveness of the diets was deemed unclear due to overlapping outcomes.
Published in
Publication details and source links for this paper.
Philip W, Mads NT, Mads JS, et al. A Fully Provided, Hypocaloric, Carbohydrate-Reduced High-Protein Diet Compared to a Hypocaloric Conventional Diabetes Diet for 6 Weeks Improved Glycemic Control to a Greater Extent. Nutrients. 2022;14(24):5244. doi:10.3390/nu14245244
The CRHP group reported a 4% lower carbohydrate intake (p ≤ 0.05).
The CRHP group had higher urea excretion by 22% (p ≤ 0.05).
Body weight loss was similar in both groups, with CRHP losing −5.5 ± 4.5 kg and CD losing −4.6 ± 4.8 kg.
Evidence network
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This study contributes evidence to Hypocaloric conventional diabetes diet (CD), Low-carbohydrate diet and Body weight, HbA1c, Carbohydrate intake, and 1 more.
This study contributes evidence to
Primary intervention
Hypocaloric conventional diabetes diet (CD)
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
3
Related topics
6
Evidence pairs
1787
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Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence relationship
Related evidence
Evidence relationship
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Evidence topic
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Core evidence
The primary outcomes reported in this study.
Hypocaloric conventional diabetes diet (CD) → Body weight
Hypocaloric conventional diabetes diet (CD) → Body weight
Hypocaloric conventional diabetes diet (CD) → HbA1c
Hypocaloric conventional diabetes diet (CD) → HbA1c
Low-carbohydrate diet → Carbohydrate intake
Low-carbohydrate diet → Carbohydrate intake
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Low-Carbohydrate Diet Education and HbA1c, Low-Carbohydrate Diet Education and Body Weight.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies on Low-Carbohydrate Diet Education
Contributes to Low-Carbohydrate Diet Education evidence base.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
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24 results
13 results
24 results
24 results
13 results
Generated from the study's connected evidence using Evidence Intelligence™.
Low-Carbohydrate Diet Education appears to affect body weight.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Body weight
EvidenceScore™ Strong | EvidenceScore™ 85.4 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 17 supporting studies with consistent results and a positive effect signal.
Low-Carbohydrate Diet Education may lower HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 86.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on 28 supporting studies with generally consistent results and a positive effect signal.
Low-carbohydrate diet appears to improve carbohydrate intake.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Carbohydrate intake
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Low-carbohydrate diet appears to improve urea excretion.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Urea excretion
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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