Last updated August 29, 2026
Key finding
Participants significantly reduced body weight at 3 months (IG: -5.9 ± 5.0%; CG: -4.2 ± 5.0%)
The study evaluated the effectiveness of the Vitadio digital therapy for obesity management, finding comparable results to intensive in-person interventions.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
The study evaluated the effectiveness of the Vitadio digital therapy for obesity management, finding comparable results to intensive in-person interventions.
This study highlights the potential of digital interventions like Vitadio to provide effective obesity management, which is crucial given the rising rates of obesity and related health issues. It offers an accessible alternative for individuals who may not have access to traditional in-person programs, potentially improving public health outcomes.
The study's sample size may limit generalizability. Long-term effects beyond 6 months were not assessed. Potential biases in self-reported data could affect results.
Published in
Publication details and source links for this paper.
Katarína M, Martina K, Maxi PB, et al. The Digital Lifestyle Intervention Vitadio Achieves Comparable Results to Intensive In-Person Obesity Management. Nutrients. 2022;14(10):2005. doi:10.3390/nu14102005
Participants in the intervention group lost 5.9% of body weight at 3 months (p < 0.01).
Body weight reduction at 6 months was 6.6% in the intervention group.
TAG levels improved by 0.6 mmol/l in the intervention group (p < 0.01).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Vitadio digital therapy and Blood triacylglycerol concentration, Body weight, Fasting Plasma Glucose (FPG), and 3 more.
This study contributes evidence to
Primary intervention
Vitadio digital therapy
Primary outcomes
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
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Related topics
6
Evidence pairs
1551
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Contributes evidence
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Contributes evidence
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Contributes evidence
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Contributes evidence
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Primary evidence
Evidence relationship
Related evidence
Evidence relationship
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Evidence relationship
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Core evidence
The primary outcomes reported in this study.
Vitadio digital therapy → Blood triacylglycerol concentration
Vitadio digital therapy → Blood triacylglycerol concentration
Vitadio digital therapy → Fasting Plasma Glucose (FPG)
Vitadio digital therapy → Fasting Plasma Glucose (FPG)
Vitadio digital therapy → Insulin resistance
Vitadio digital therapy → Insulin resistance
Evidence Library
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Digital Lifestyle Interventions and HbA1c, Digital Lifestyle Interventions and Blood triacylglycerol concentration.
This study contributes to the evidence on the following intervention-outcome relationships.
Devices & Technology
Devices & Technology
Devices & Technology
Curated evidence collections and hubs this study is part of.
All studies on Digital Lifestyle Interventions
Contributes to Digital Lifestyle Interventions evidence base.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies measuring Blood triacylglycerol concentration
Measures Blood triacylglycerol concentration as a key outcome.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
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2 results
1 results
2 results
2 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Digital Lifestyle Interventions appears to affect body weight.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 7 supporting studies with consistent results and a positive effect signal.
Digital Lifestyle Interventions appears to lower HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 6 supporting studies with consistent results and a positive effect signal.
Digital Lifestyle Interventions may improve fasting glucose.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Digital Lifestyle Interventions may improve insulin resistance.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Insulin resistance
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.
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