Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
Ebenatide improves glycemic control in type 2 diabetes
Last updated July 18, 2026
Key finding
HbA1c decreased significantly from baseline.
Ebenatide treatment significantly improved glycemic control and body composition in participants with Type 2 Diabetes Mellitus over 52 weeks.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
Ebenatide treatment significantly improved glycemic control and body composition in participants with Type 2 Diabetes Mellitus over 52 weeks.
Clinical relevance
Improving glycemic control and body composition is crucial for managing Type 2 Diabetes Mellitus, as it can reduce the risk of complications associated with the disease. The significant findings from this study suggest that Ebenatide may offer a beneficial treatment option for patients, potentially leading to better long-term health outcomes and quality of life.
Keep in mind
The study's sample size may limit the generalizability of the findings. Long-term effects beyond 52 weeks were not assessed. The study did not include a diverse population, which may affect applicability.
Published in
Journal Reference
Publication details and source links for this paper.
Cheng-lan X, Xiao-cen K, Xiao-mei L, Xiao-hua X, Bing-li L, Jian-hua M. Ebenatide Treatment Improves Glycemic Control and Body Composition in Type 2 Diabetes Mellitus. Frontiers in Endocrinology. 2025;16:1622526. doi:10.3389/fendo.2025.1622526
Main Effects
Ebenatide reduced HbA1c by 1.18% at Week 52 (P < 0.001).
Mean blood glucose decreased by 2.31 mmol/L at Week 52 (P < 0.001).
Body weight declined significantly at both Week 24 and Week 52 (P < 0.05).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Ebenatide and BMI, Blood glucose, Body fat mass, and 10 more.
This study contributes evidence to
Primary intervention
Ebenatide
Primary outcomes
- BMI
- Blood glucose
- Body fat mass
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
13
Evidence pairs
13
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 72
3
Related topics
13
Evidence pairs
732
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 13 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
Glycemic Control
matched_outcome
Related evidence
Evidence topic
Weight Loss
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerChange in waist-to-height ratio after dietary intervention
Ebenatide → Change in waist-to-height ratio after dietary intervention
Ebenatide → Change in waist-to-height ratio after dietary intervention
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Evidence Suggest
- HbA1c levels decreased significantly, indicating improved glycemic control.
- Body weight and fat mass reductions were statistically significant.
- Ebenatide treatment improved time in range for blood glucose levels.
Who this applies to
- Adults diagnosed with Type 2 Diabetes Mellitus.
- Individuals seeking additional treatment options for glycemic control.
Keep in Mind
- Results may not be applicable to populations outside the study's demographics.
- Further research is needed to evaluate long-term outcomes.
- The study did not explore potential side effects of Ebenatide.
Between the Lines
- The study's sample size may limit the generalizability of the findings.
- Long-term effects beyond 52 weeks were not assessed.
- The study did not include a diverse population, which may affect applicability.
Evidence Library
Build your evidence library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Ebenatide and Fasting Glucose, Ebenatide and Body Mass Index.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Medications
Ebenatide → Fasting Glucose
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceMedications
Ebenatide → Body Mass Index
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceMedications
Ebenatide → Body Weight
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Body Mass Index Evidence Hub
All studies measuring Body Mass Index
1 studies
outcome_hubMeasures Body Mass Index as a key outcome.
Body Weight Evidence Hub
All studies measuring Body Weight
1 studies
outcome_hubMeasures Body Weight as a key outcome.
Ebenatide Evidence Hub
All studies on Ebenatide
1 studies
intervention_hubContributes to Ebenatide evidence base.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
1 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Ebenatide and Blood glucose
Intervention: EbenatideOutcome: Blood glucose
1 results
All studies on Ebenatide and BMI
Intervention: EbenatideOutcome: BMI
1 results
All studies on Ebenatide
Intervention: Ebenatide
1 results
All studies measuring Blood glucose
Outcome: Blood glucose
1 results
All studies measuring BMI
Outcome: BMI
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Ebenatide affect bmi?
Emerging Evidence
Ebenatide appears to improve BMI.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
BMI
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Ebenatide improve blood glucose?
Emerging Evidence
Ebenatide appears to improve Blood glucose.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Blood glucose
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Ebenatide improve body fat mass?
Emerging Evidence
Ebenatide appears to improve Body fat mass.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Body fat mass
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Ebenatide affect body weight?
Emerging Evidence
Ebenatide appears to improve Body weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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