Last updated September 1, 2026
Key finding
Sustained SIAP2 consumption significantly decreased the insulin by -5.25 mg/dL.
This study evaluated the effects of enriched seafood sticks on risk factors for cardiovascular disease in abdominally obese individuals, finding significant reductions in insulin and pulse pressure.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the effects of enriched seafood sticks on risk factors for cardiovascular disease in abdominally obese individuals, finding significant reductions in insulin and pulse pressure.
These findings suggest that dietary interventions using enriched seafood could be a beneficial strategy for managing cardiovascular risk factors in individuals with abdominal obesity, a population at high risk for metabolic disorders. Improved insulin sensitivity and lower blood pressure can contribute to better overall health outcomes.
Unclear effectiveness of interventions due to lack of statistical significance. Limited generalizability as the study focused on a specific population. Potential confounding factors not controlled for in the analysis.
Published in
Publication details and source links for this paper.
Judit C, Lorena C, Laura P, et al. Effects of enriched seafood sticks with postbiotic and bioactive compounds on CMD risk factors and gut microbiota in abdominally obese individuals. European Journal of Nutrition. 2022;61(7):3597-3611. doi:10.1007/s00394-022-02904-0
Sustained SIAP2 consumption significantly decreased insulin by -5.25 mg/dL.
HOMA-IR decreased by -1.33, indicating improved insulin resistance.
In women, SIAP2 consumption significantly decreased pulse pressure by -4.69 mmHg.
Postprandial circulating triglyceride levels increased less with SIAP2 [23.9 mg/dL] compared to placebo [49.0 mg/dL].
Evidence network
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This study contributes evidence to Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) and Insulin, Insulin resistance, Postprandial circulating triglyceride, and 1 more.
This study contributes evidence to
Primary intervention
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2)
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
4
Evidence pairs
140
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Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Core evidence
The primary outcomes reported in this study.
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Insulin
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Insulin
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Insulin resistance
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Insulin resistance
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Postprandial circulating triglyceride
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Postprandial circulating triglyceride
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Pulse pressure
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) → Pulse pressure
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) and Insulin Resistance, Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) and Insulin Resistance.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Blood Pressure
Measures Blood Pressure as a key outcome.
All studies on Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2)
Contributes to Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) evidence base.
All studies measuring Insulin Resistance
Measures Insulin Resistance as a key outcome.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) appears to improve insulin.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Insulin
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) appears to improve insulin resistance.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Insulin resistance
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) appears to improve postprandial circulating triglyceride.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Postprandial circulating triglyceride
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Enriched seafood sticks with postbiotic and bioactive compounds (SIAP2) appears to improve pulse pressure.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Pulse pressure
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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