Last updated August 15, 2026
Key finding
Fasting blood glucose concentrations showed a significant decrease among both the groups, with a reduction of 30 and 35 mg/dL in the LTPA and HBRT groups, respectively, after 8 weeks.
This study evaluated the effects of home-based resistance training and leisure-time physical activity on children with Type 1 diabetes, finding significant reductions in fasting plasma glucose levels.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the effects of home-based resistance training and leisure-time physical activity on children with Type 1 diabetes, finding significant reductions in fasting plasma glucose levels.
These findings are clinically significant as they suggest that structured physical activity can help manage blood glucose levels in children with Type 1 diabetes. This could lead to better long-term health outcomes and reduce the risk of diabetes-related complications.
The study's sample size and demographics may limit generalizability. Effectiveness of interventions was not clearly established for all outcomes. Potential confounding variables were not fully controlled.
Published in
Publication details and source links for this paper.
Maryam N, Vazgen M, Silva H. Effects of Home-Based Resistance Training and Leisure-Time Physical Activity on Children with Type 1 Diabetes. Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences. 2025;30:58. doi:10.4103/jrms.jrms_582_24
Fasting plasma glucose decreased by 30 mg/dL in the LTPA group and 35 mg/dL in the HBRT group (p = 0.027).
Maximum oxygen consumption increased significantly (P ≤ 0.05).
Serum glucagon-like peptide-1 levels significantly increased in both groups.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Exercise therapy, Resistance training and Fasting Plasma Glucose (FPG), GLP-1, HbA1c, and 2 more.
This study contributes evidence to
Primary intervention
Exercise therapy
Primary outcomes
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
4
Related topics
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Evidence pairs
956
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Contributes evidence
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Primary evidence
Evidence topic
matched_intervention_and_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Exercise therapy → Fasting Plasma Glucose (FPG)
Exercise therapy → Fasting Plasma Glucose (FPG)
Resistance training → Fasting Plasma Glucose (FPG)
Resistance training → Fasting Plasma Glucose (FPG)
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Exercise therapy and HbA1c, Resistance training and HbA1c.
This study contributes to the evidence on the following intervention-outcome relationships.
Physical Activity
Physical Activity
Curated evidence collections and hubs this study is part of.
All studies on Exercise therapy
Contributes to Exercise therapy evidence base.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies on Resistance training
Contributes to Resistance training evidence base.
Latest published studies
Published within the last 2 years.
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8 results
3 results
8 results
3 results
8 results
Generated from the study's connected evidence using Evidence Intelligence™.
Exercise therapy may improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 82.9 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Resistance training may improve HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Resistance training appears to improve Fasting Plasma Glucose (FPG).
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Exercise therapy appears to improve VO2 max.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
VO2 max
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
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