StrongDecrease
HbA1c
DSMES → HbA1c
DSMES → HbA1c
Evidence profile
StrongDecreaseGlycemic Control
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Research Summary
Analyzed using Evidence Intelligence™
Family-DSMES improves diabetes outcomes in diverse adults
Key finding
Mean decrease in HbA1c at immediate post-intervention.
This study compared Family-DSMES and Standard-DSMES in participants with diabetes, finding significant improvements in diabetes-related family involvement with Family-DSMES.
Evidence strength
Moderate confidence
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Some Concerns bias
Last updated July 8, 2026Quick read
Study at a glance
The essential study design details in one scan.
Population
Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes
Intervention
Family-DSMES, Standard-DSMES
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Primary outcome
Hemoglobin A1c
Comparator
Standard-DSMES
Plain-language summary
What this paper says
A plain-language read of the study's main message and where it applies.
Study focus
This study compared Family-DSMES and Standard-DSMES in participants with diabetes, finding significant improvements in diabetes-related family involvement with Family-DSMES.
Clinical relevance
This research highlights the importance of family involvement in diabetes management, suggesting that educational programs that include family members may lead to better health outcomes for individuals with diabetes. Improved family support can enhance motivation and adherence to treatment, ultimately leading to better management of diabetes.
Keep in mind
Effectiveness of interventions remains unclear due to unspecified limitations. Potential biases in participant selection or reporting. Generalizability may be limited to specific populations.
Published in
Journal Reference
Publication details and source links for this paper.
Jennifer AA, Pearl AM, James PS, et al. Family-DSMES vs. Standard-DSMES: A Comparative Effectiveness-Implementation RCT. Diabetes research and clinical practice. 2026;232:113063-113063. doi:10.1016/j.diabres.2025.113063
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Main Effects
Both Family-DSMES and Standard-DSMES reduced Hemoglobin A1c by -0.77% (p < 0.005).
Family-DSMES significantly improved diabetes-related family involvement compared to Standard-DSMES (p = 0.024).
Both interventions demonstrated a consistent decrease in Hemoglobin A1c levels at all time points.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to DSMES and HbA1c, Improvement in diabetes-related helpful family involvement.
This study contributes evidence to
Primary intervention
DSMES
Primary outcomes
- HbA1c
- Improvement in diabetes-related helpful family involvement
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
2
Evidence pairs
2
Relationships
2
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 60
2
Related topics
2
Evidence pairs
204
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 2 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Core evidence
Study findings
The primary outcomes reported in this study.
StrongIncrease
Improvement in diabetes-related helpful family involvement
DSMES → Improvement in diabetes-related helpful family involvement
DSMES → Improvement in diabetes-related helpful family involvement
Evidence profile
StrongIncreasePatient-Reported
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Evidence Suggest
- Family-DSMES improved family involvement by 0.39 units (p = 0.024).
- Both groups achieved a significant decrease in Hemoglobin A1c levels.
- Family-DSMES showed a consistent reduction in blood sugar levels.
Who this applies to
- Individuals with diabetes seeking better management strategies.
- Families of patients with diabetes involved in care.
Keep in Mind
- Results may not apply to all demographics or diabetes types.
- Further research is needed to confirm long-term benefits.
- Study design limitations may affect the interpretation of findings.
Between the Lines
- Effectiveness of interventions remains unclear due to unspecified limitations.
- Potential biases in participant selection or reporting.
- Generalizability may be limited to specific populations.
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Diabetes Self-Management Education and Support (DSMES) Programs and HbA1c, Diabetes Self-Management Education and Support (DSMES) Programs and Improvement in diabetes-related helpful family involvement.
Related evidence relationships
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention-outcome relationships.
Diabetes Self-Management Education and Support (DSMES) ProgramsHbA1c
Behavioral & Lifestyle
4 studies
Detailed evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Diabetes Self-Management Education and Support (DSMES) Programs Evidence Hub
All studies on Diabetes Self-Management Education and Support (DSMES) Programs
4 studies
intervention_hubContributes to Diabetes Self-Management Education and Support (DSMES) Programs evidence base.
HbA1c Evidence Hub
All studies measuring HbA1c
4 studies
outcome_hubMeasures HbA1c as a key outcome.
Improvement in diabetes-related helpful family involvement Evidence Hub
All studies measuring Improvement in diabetes-related helpful family involvement
1 studies
outcome_hubMeasures Improvement in diabetes-related helpful family involvement as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in the evidence archive
Jump to pre-filtered views in the evidence archive.
All studies on DSMES and HbA1c
Intervention: DSMESOutcome: HbA1c
4 results
All studies on DSMES and Improvement in diabetes-related helpful family involvement
Intervention: DSMESOutcome: Improvement in diabetes-related helpful family involvement
1 results
All studies on DSMES
Intervention: DSMES
4 results
All studies measuring HbA1c
Outcome: HbA1c
4 results
All studies measuring Improvement in diabetes-related helpful family involvement
Outcome: Improvement in diabetes-related helpful family involvement
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Diabetes Self-Management Education and Support (DSMES) Programs improve HbA1c?
Emerging Evidence
Diabetes Self-Management Education and Support (DSMES) Programs may improve HbA1c.
ConsensusScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 53.5 | moderate positive | ConsensusScore™ Consistent | 1 study
Why this answer: This answer is based on 24 supporting studies with generally consistent results and a positive effect signal.
Limitations
- Population details are unavailable.
Does DSMES improve improvement in diabetes-related helpful family involvement?
Emerging Evidence
DSMES appears to improve Improvement in diabetes-related helpful family involvement.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Improvement in diabetes-related helpful family involvement
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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