Last updated September 2, 2026
Key finding
Postprandial glucose concentrations during the MTT exhibited a significant treatment by time interaction (P = 0.045).
This study investigated the effects of increased resistant starch consumption on insulin sensitivity and glucose control in individuals with type 2 diabetes, revealing mixed outcomes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of increased resistant starch consumption on insulin sensitivity and glucose control in individuals with type 2 diabetes, revealing mixed outcomes.
Understanding how dietary changes, like increasing resistant starch, affect glucose control is crucial for managing type 2 diabetes. While some outcomes were promising, the lack of significant improvements in insulin sensitivity suggests that dietary interventions alone may not be sufficient for optimal diabetes management.
The study had a limited sample size, affecting generalizability. No significant effects on overall insulin sensitivity were observed. The long-term impact of resistant starch consumption was not assessed.
Published in
Publication details and source links for this paper.
C LB, L S, E LT, et al. Effects of increased resistant starch consumption on insulin sensitivity and glucose control in type 2 diabetes. Endocrine Connections. 2014;3(2):75-84. doi:10.1530/EC-14-0036
Postprandial glucose concentrations decreased significantly (P = 0.045).
Fasting non-esterified fatty acids (NEFA) concentrations were significantly lower (P = 0.004).
Fasting triglycerides (TG) concentrations increased significantly (P = 0.039).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Amioca starch control, Resistant starch (HAM-RS2) and Glucose iAUC (OGTT), Change in non-esterified fatty acids levels, Fasting GLP1, and 8 more.
This study contributes evidence to
Primary intervention
Amioca starch control
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
3
Related topics
11
Evidence pairs
1045
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Amioca starch control → Glucose iAUC (OGTT)
Amioca starch control → Glucose iAUC (OGTT)
Resistant starch (HAM-RS2) → Change in non-esterified fatty acids levels
Resistant starch (HAM-RS2) → Change in non-esterified fatty acids levels
Resistant starch (HAM-RS2) → Fasting triglycerides (TG)
Resistant starch (HAM-RS2) → Fasting triglycerides (TG)
Resistant starch (HAM-RS2) → Glucose uptake across forearm muscle
Resistant starch (HAM-RS2) → Glucose uptake across forearm muscle
Resistant starch (HAM-RS2) → Insulin sensitivity
Resistant starch (HAM-RS2) → Insulin sensitivity
Resistant starch (HAM-RS2) → Peripheral insulin sensitivity
Resistant starch (HAM-RS2) → Peripheral insulin sensitivity
Resistant starch (HAM-RS2) → Postprandial blood glucose
Resistant starch (HAM-RS2) → Postprandial blood glucose
Resistant starch (HAM-RS2) → Postprandial GLP1 excursions
Resistant starch (HAM-RS2) → Postprandial GLP1 excursions
Resistant starch (HAM-RS2) → Soleus Intramuscular Triglyceride Concentrations
Resistant starch (HAM-RS2) → Soleus Intramuscular Triglyceride Concentrations
Evidence Library
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Resistant starch (HAM-RS2) and Insulin Resistance, Resistant starch (HAM-RS2) and Postprandial and OGTT Glucose.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Insulin Resistance
Measures Insulin Resistance as a key outcome.
All studies measuring Postprandial and OGTT Glucose
Measures Postprandial and OGTT Glucose as a key outcome.
All studies on Resistant starch (HAM-RS2)
Contributes to Resistant starch (HAM-RS2) evidence base.
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2 results
2 results
2 results
2 results
2 results
Generated from the study's connected evidence using Evidence Intelligence™.
Resistant starch (HAM-RS2) appears to improve postprandial blood glucose.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Postprandial blood glucose
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Resistant starch (HAM-RS2) for insulin sensitivity.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Insulin sensitivity
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | neutral | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Resistant starch (HAM-RS2) appears to improve change in non-esterified fatty acids levels.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Change in non-esterified fatty acids levels
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Resistant starch (HAM-RS2) appears to improve postprandial glp1 excursions.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Postprandial GLP1 excursions
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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