Last updated August 22, 2026
Key finding
MAGE was lower over lunch with RS (0.94 mmol/L; p = 0.004).
Substituting ~15% of dietary starch with resistant starch in adults with type 2 diabetes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
Substituting ~15% of dietary starch with resistant starch in adults with type 2 diabetes.
This study evaluated Substituting ~15% of dietary starch with resistant starch in adults with type 2 diabetes.
Limitations were not clearly described in the extracted text.
Published in
Publication details and source links for this paper.
Sineaid MC, M. BE, Martin BW, M. DR. Substituting dietary starch with resistant starch lowers blood glucose in adults with type 2 diabetes. Diabetic Medicine. 2025;42(9):e70079. doi:10.1111/dme.70079
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Resistant starch (HAM-RS2) and Mean amplitude of glycemic excursions (MAGE), Peak insulin levels during oral glucose tolerance test (OGTT), Standard deviation of glucose, and 2 more.
This study contributes evidence to
Primary intervention
Resistant starch (HAM-RS2)
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
5
Evidence pairs
352
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Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Core evidence
The primary outcomes reported in this study.
Resistant starch (HAM-RS2) → Mean amplitude of glycemic excursions (MAGE)
Resistant starch (HAM-RS2) → Mean amplitude of glycemic excursions (MAGE)
Resistant starch (HAM-RS2) → Peak insulin levels during oral glucose tolerance test (OGTT)
Resistant starch (HAM-RS2) → Peak insulin levels during oral glucose tolerance test (OGTT)
Resistant starch (HAM-RS2) → Standard deviation of glucose
Resistant starch (HAM-RS2) → Standard deviation of glucose
Resistant starch (HAM-RS2) → Time to Peak Glycemia
Resistant starch (HAM-RS2) → Time to Peak Glycemia
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Resistant starch (HAM-RS2) and Glucose Variability, Resistant starch (HAM-RS2) and Peak insulin levels during oral glucose tolerance test (OGTT).
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Glucose Variability
Measures Glucose Variability as a key outcome.
All studies measuring Peak insulin levels during oral glucose tolerance test (OGTT)
Measures Peak insulin levels during oral glucose tolerance test (OGTT) as a key outcome.
All studies on Resistant starch (HAM-RS2)
Contributes to Resistant starch (HAM-RS2) evidence base.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Resistant starch (HAM-RS2) appears to improve Mean amplitude of glycemic excursions (MAGE).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Mean amplitude of glycemic excursions (MAGE)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Resistant starch (HAM-RS2) appears to improve Standard deviation of glucose.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Standard deviation of glucose
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Resistant starch (HAM-RS2) appears to improve Time in range.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Time in range
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Resistant starch (HAM-RS2) appears to improve Time to Peak Glycemia.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Time to Peak Glycemia
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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