Research Summary
Analyzed using Evidence Intelligence™

Insulin therapy improves glycemic control in hospitalized T2D patients

Last updated July 12, 2026

Key finding

52.2% of blood glucose measurements were within the target range.

This study evaluated the use of insulin degludec and insulin aspart guided by a clinical decision support system for glycemic control in hospitalized patients with type 2 diabetes, finding a significant percentage of blood glucose measurements within target range.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the use of insulin degludec and insulin aspart guided by a clinical decision support system for glycemic control in hospitalized patients with type 2 diabetes, finding a significant percentage of blood glucose measurements within target range.

Clinical relevance

Effective glycemic control in hospitalized patients with type 2 diabetes is crucial to prevent complications and improve recovery outcomes. This study highlights the potential of using a clinical decision support system to optimize insulin therapy, which can lead to better management of blood glucose levels in a hospital setting, ultimately enhancing patient care.

Keep in mind

The study design was non-randomized, which may introduce bias. Results may not be generalizable to all hospitalized patients with diabetes. Limited follow-up duration may not capture long-term effects.

Published in

Journal Reference

Publication details and source links for this paper.

Felix A, Daniel AH, Petra MB, et al. Glycemic Control Using Insulin Degludec and Insulin Aspart Guided by a Clinical Decision Support System in Hospitalized Patients with Type 2 Diabetes. Biosensors. 2026;16(5):289. doi:10.3390/bios16050289

Main Effects

52.2% of blood glucose measurements were within the target range.

Mean blood glucose decreased from 11.9 ± 4.4 mmol/L to 7.5 ± 1.9 mmol/L after 6 days.

Adherence to insulin dosing recommendations was 94.2%.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Insulin therapy and Adherence to insulin dosing recommendations, Blood glucose, Percentage of blood glucose measurements within target range of 3.9–7.8 mmol/L, and 1 more.

Primary intervention

Insulin therapy

Primary outcomes

  • Adherence to insulin dosing recommendations
  • Blood glucose
  • Percentage of blood glucose measurements within target range of 3.9–7.8 mmol/L

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

2

Related topics

4

Evidence pairs

184

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence relationship

Insulin Therapies and Fasting Glucose

Related evidence

Evidence topic

Glycemic Control

Save evidence

Evidence topic

Insulin Therapies

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Adherence to insulin dosing recommendations

Insulin therapy → Adherence to insulin dosing recommendations

Insulin therapy → Adherence to insulin dosing recommendations

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Blood glucose

Insulin therapy → Blood glucose

Insulin therapy → Blood glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Percentage of blood glucose measurements within target range of 3.9–7.8 mmol/L

Insulin therapy → Percentage of blood glucose measurements within target range of 3.9–7.8 mmol/L

Insulin therapy → Percentage of blood glucose measurements within target range of 3.9–7.8 mmol/L

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Percentage of hypoglycemic events

Insulin therapy → Percentage of hypoglycemic events

Insulin therapy → Percentage of hypoglycemic events

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • 52.2% of blood glucose measurements were within target range.
  • Mean blood glucose improved by 4.4 mmol/L after 6 days of treatment.
  • Only 1.25% of glucose values were classified as hypoglycemic.
who this applies

Who this applies to

  • Hospitalized patients with type 2 diabetes.
  • Patients requiring insulin therapy for glycemic control.
keep in mind

Keep in Mind

  • The study's non-randomized design limits causal inferences.
  • Results may not apply to outpatient settings or other diabetes types.
  • Short treatment duration may not reflect long-term management outcomes.
between the lines

Between the Lines

  • The study design was non-randomized, which may introduce bias.
  • Results may not be generalizable to all hospitalized patients with diabetes.
  • Limited follow-up duration may not capture long-term effects.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Insulin Therapies and Adherence to insulin dosing recommendations, Insulin Therapies and Fasting Glucose.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Insulin Therapies improve fasting glucose?

Strong Evidence

Insulin Therapies appears to improve Fasting Glucose.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Blood glucose

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 5 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
5 supporting studiesUpdated: Jul 2026

Does Insulin therapy improve adherence to insulin dosing recommendations?

Emerging Evidence

Insulin therapy appears to improve Adherence to insulin dosing recommendations.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Adherence to insulin dosing recommendations

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Insulin therapy improve percentage of blood glucose measurements within target range of 3.9–7.8 mmol/l?

Emerging Evidence

Insulin therapy appears to improve Percentage of blood glucose measurements within target range of 3.9–7.8 mmol/L.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Percentage of blood glucose measurements within target range of 3.9–7.8 mmol/L

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Insulin therapy affect percentage of hypoglycemic events?

Emerging Evidence

Current evidence does not show a clear benefit of Insulin therapy for Percentage of hypoglycemic events.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Percentage of hypoglycemic events

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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