Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
Long BPL-RYGB improves HbA1c and weight loss in T2D patients
Last updated July 14, 2026
Key finding
Patients in the long BPL-RYGB group showed a -0.33% greater decrease in HbA1c (95% CI [-0.60, -0.06], p = 0.018).
This study compared Long Biliopancreatic Limb Roux-en-Y Gastric Bypass (BPL-RYGB) to Long Alimentary Limb Roux-en-Y Gastric Bypass (AL-RYGB) in adults with obesity and Type 2 diabetes, finding a greater decrease in HbA1c with BPL-RYGB.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study compared Long Biliopancreatic Limb Roux-en-Y Gastric Bypass (BPL-RYGB) to Long Alimentary Limb Roux-en-Y Gastric Bypass (AL-RYGB) in adults with obesity and Type 2 diabetes, finding a greater decrease in HbA1c with BPL-RYGB.
Clinical relevance
Understanding the differences in outcomes between these two surgical approaches is crucial for clinicians when recommending treatment options for obese patients with Type 2 diabetes. The greater reduction in HbA1c with Long BPL-RYGB suggests it may be a more effective option for improving glycemic control.
Keep in mind
The study did not report on long-term outcomes beyond the immediate post-operative period. Sample size and demographic diversity were not specified, which may limit generalizability. Potential confounding factors were not fully controlled for in the analysis.
Published in
Journal Reference
Publication details and source links for this paper.
Lena S, Roland M, Yusef M, et al. Comparison of Long Biliopancreatic Limb Roux-en-Y Gastric Bypass to Long Alimentary Limb Roux-en-Y Gastric Bypass on Type 2 Diabetes in Adults with Obesity. Obesity Surgery. 2026;36(6):2976-2986. doi:10.1007/s11695-026-08690-6
Main Effects
Long BPL-RYGB showed a -0.33% greater decrease in HbA1c (95% CI [-0.60, -0.06], p = 0.018).
Both procedures improved body weight, BMI, and waist-to-hip ratio.
No statistically significant differences in T2D remission rates were observed (p=0.113).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Long AL-RYGB, Long BPL-RYGB and BMI, Body weight, Fasting insulin levels, and 3 more.
This study contributes evidence to
Primary intervention
Long AL-RYGB
Primary outcomes
- BMI
- Body weight
- Fasting insulin levels
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
12
Evidence pairs
12
Relationships
2
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
2
Related topics
12
Evidence pairs
462
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 12 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
Weight Loss
matched_outcome
Related evidence
Evidence topic
HbA1c Reduction
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerT2D remission rate at 12 months
Long AL-RYGB → T2D remission rate at 12 months
Long AL-RYGB → T2D remission rate at 12 months
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerT2D remission rate at 12 months
Long BPL-RYGB → T2D remission rate at 12 months
Long BPL-RYGB → T2D remission rate at 12 months
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
Build your evidence library
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Evidence Suggest
- Long BPL-RYGB resulted in a -0.33% decrease in HbA1c, indicating better glycemic control.
- Both surgical methods led to improvements in body weight and BMI.
- No significant differences in T2D remission rates were found between the two groups.
Who this applies to
- Adults with obesity and Type 2 diabetes seeking surgical weight loss options.
- Patients who have not achieved adequate glycemic control with lifestyle changes or medications.
Keep in Mind
- Results may not apply to populations outside the study's demographic.
- The study's findings are limited to short-term outcomes and may not reflect long-term efficacy.
- Further research is needed to explore the long-term impacts of each surgical approach.
Between the Lines
- The study did not report on long-term outcomes beyond the immediate post-operative period.
- Sample size and demographic diversity were not specified, which may limit generalizability.
- Potential confounding factors were not fully controlled for in the analysis.
Evidence Library
Build your evidence library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Long AL-RYGB and Body Mass Index, Long AL-RYGB and Body Weight.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Procedures
Long AL-RYGB → Body Mass Index
Procedures
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceProcedures
Long AL-RYGB → Body Weight
Procedures
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Body Mass Index Evidence Hub
All studies measuring Body Mass Index
1 studies
outcome_hubMeasures Body Mass Index as a key outcome.
Body Weight Evidence Hub
All studies measuring Body Weight
1 studies
outcome_hubMeasures Body Weight as a key outcome.
Long AL-RYGB Evidence Hub
All studies on Long AL-RYGB
1 studies
intervention_hubContributes to Long AL-RYGB evidence base.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Long AL-RYGB and BMI
Intervention: Long AL-RYGBOutcome: BMI
1 results
All studies on Long AL-RYGB and Body weight
Intervention: Long AL-RYGBOutcome: Body weight
1 results
All studies on Long AL-RYGB
Intervention: Long AL-RYGB
1 results
All studies measuring BMI
Outcome: BMI
1 results
All studies measuring Body weight
Outcome: Body weight
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Long AL-RYGB affect bmi?
Emerging Evidence
Long AL-RYGB appears to improve BMI.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
BMI
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Long AL-RYGB affect body weight?
Emerging Evidence
Long AL-RYGB appears to improve Body weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Long AL-RYGB improve fasting insulin levels?
Emerging Evidence
Long AL-RYGB appears to improve Fasting insulin levels.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Fasting insulin levels
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Long AL-RYGB improve HbA1c?
Emerging Evidence
Long AL-RYGB appears to improve HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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