Research Summary
Analyzed using Evidence Intelligence™

Physical activity intervention improves glycaemic control in individuals with abnormal glucose tolerance

Last updated July 18, 2026

Key finding

Participants in the intervention group demonstrated a 1.18% reduction in HbA1c (95% CI, -1.65, -0.71).

This pilot randomized controlled trial evaluated a 12-week device-measured physical activity intervention on glycaemic control and visual functioning in individuals newly diagnosed with AGT in Ghana, finding a significant reduction in HbA1c levels.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This pilot randomized controlled trial evaluated a 12-week device-measured physical activity intervention on glycaemic control and visual functioning in individuals newly diagnosed with AGT in Ghana, finding a significant reduction in HbA1c levels.

Clinical relevance

This study highlights the potential of structured physical activity interventions in managing glycaemic control among newly diagnosed AGT patients. Given the rising prevalence of diabetes in Ghana, effective lifestyle interventions could play a crucial role in improving health outcomes and reducing the risk of diabetes-related complications.

Keep in mind

The study had a small sample size, limiting generalizability. Effectiveness of the general health education intervention remains unclear. Statistical significance for contrast sensitivity improvements was not established.

Published in

Journal Reference

Publication details and source links for this paper.

Ebenezer OA, Thomas H, Stephen O, et al. Pilot randomized controlled trial assessing the feasibility of a 12-week device-measured physical activity intervention on glycaemic control and visual functioning among individuals newly diagnosed with AGT in Ghana. Pilot and Feasibility Studies. 2026;12:56. doi:10.1186/s40814-026-01805-x

Main Effects

Intervention group demonstrated a 1.18% reduction in HbA1c (95% CI, -1.65, -0.71).

Control group showed a reduction in HbA1c of -0.57 (95% CI, -1.37, 0.23).

Improvements in contrast sensitivity in the right eye (Δ = 0.029; 95% CI, -0.11, 0.17).

Improvements in contrast sensitivity in the left eye (Δ = 0.046; 95% CI, -0.09, 0.19).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Exercise therapy, Synchronous online type 1 diabetes psychoeducational program for school staff and HbA1c, Improvement in contrast sensitivity in the left eye, Improvement in contrast sensitivity in the right eye.

Primary intervention

Exercise therapy

Primary outcomes

  • HbA1c
  • Improvement in contrast sensitivity in the left eye
  • Improvement in contrast sensitivity in the right eye

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

2

Related topics

4

Evidence pairs

371

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Diabetes Self-Management Education and Support (DSMES) Programs and HbA1c

Related evidence

Evidence topic

HbA1c Reduction

Save evidence

Evidence topic

Diabetes Self-Management Education and Support

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

HbA1c

Exercise therapy → HbA1c

Exercise therapy → HbA1c

Evidence Intelligence™
EvidenceScore™
81
Strong
ImpactScore™
79
Positive
ConsistencyScore™
86
consistent
Supporting studies: Based on 7 studies
Add to Evidence Tracker

Improvement in contrast sensitivity in the left eye

Exercise therapy → Improvement in contrast sensitivity in the left eye

Exercise therapy → Improvement in contrast sensitivity in the left eye

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Improvement in contrast sensitivity in the right eye

Exercise therapy → Improvement in contrast sensitivity in the right eye

Exercise therapy → Improvement in contrast sensitivity in the right eye

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Synchronous online type 1 diabetes psychoeducational program for school staff → HbA1c

Synchronous online type 1 diabetes psychoeducational program for school staff → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Device-measured physical activity led to a significant 1.18% decrease in HbA1c.
  • Control group showed a smaller reduction in HbA1c of -0.57%.
  • Contrast sensitivity improvements were noted but lacked statistical significance.
who this applies

Who this applies to

  • Individuals newly diagnosed with AGT.
  • Patients in Ghana seeking lifestyle interventions for diabetes management.
keep in mind

Keep in Mind

  • Findings may not be applicable to populations outside Ghana.
  • The study's small sample size may affect the reliability of the results.
  • Further research is needed to confirm the effectiveness of the interventions.
between the lines

Between the Lines

  • The study had a small sample size, limiting generalizability.
  • Effectiveness of the general health education intervention remains unclear.
  • Statistical significance for contrast sensitivity improvements was not established.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Exercise therapy and HbA1c, Exercise therapy and Improvement in contrast sensitivity in the left eye.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Diabetes Self-Management Education and Support (DSMES) Programs improve HbA1c?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve HbA1c.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 32 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
32 supporting studiesUpdated: Jul 2026

Does Exercise therapy improve HbA1c?

Strong Evidence

Exercise therapy may improve HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 81.3 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Exercise therapy improve improvement in contrast sensitivity in the left eye?

Emerging Evidence

Exercise therapy appears to improve Improvement in contrast sensitivity in the left eye.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Improvement in contrast sensitivity in the left eye

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Exercise therapy improve improvement in contrast sensitivity in the right eye?

Emerging Evidence

Exercise therapy appears to improve Improvement in contrast sensitivity in the right eye.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Improvement in contrast sensitivity in the right eye

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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