- EvidenceScore™
- 81
- Strong
- ImpactScore™
- 79
- Positive
- ConsistencyScore™
- 86
- consistent
Physical activity intervention improves glycaemic control in individuals with abnormal glucose tolerance
Last updated July 18, 2026
Key finding
Participants in the intervention group demonstrated a 1.18% reduction in HbA1c (95% CI, -1.65, -0.71).
This pilot randomized controlled trial evaluated a 12-week device-measured physical activity intervention on glycaemic control and visual functioning in individuals newly diagnosed with AGT in Ghana, finding a significant reduction in HbA1c levels.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This pilot randomized controlled trial evaluated a 12-week device-measured physical activity intervention on glycaemic control and visual functioning in individuals newly diagnosed with AGT in Ghana, finding a significant reduction in HbA1c levels.
Clinical relevance
This study highlights the potential of structured physical activity interventions in managing glycaemic control among newly diagnosed AGT patients. Given the rising prevalence of diabetes in Ghana, effective lifestyle interventions could play a crucial role in improving health outcomes and reducing the risk of diabetes-related complications.
Keep in mind
The study had a small sample size, limiting generalizability. Effectiveness of the general health education intervention remains unclear. Statistical significance for contrast sensitivity improvements was not established.
Published in
Journal Reference
Publication details and source links for this paper.
Ebenezer OA, Thomas H, Stephen O, et al. Pilot randomized controlled trial assessing the feasibility of a 12-week device-measured physical activity intervention on glycaemic control and visual functioning among individuals newly diagnosed with AGT in Ghana. Pilot and Feasibility Studies. 2026;12:56. doi:10.1186/s40814-026-01805-x
Main Effects
Intervention group demonstrated a 1.18% reduction in HbA1c (95% CI, -1.65, -0.71).
Control group showed a reduction in HbA1c of -0.57 (95% CI, -1.37, 0.23).
Improvements in contrast sensitivity in the right eye (Δ = 0.029; 95% CI, -0.11, 0.17).
Improvements in contrast sensitivity in the left eye (Δ = 0.046; 95% CI, -0.09, 0.19).
Evidence network
How this study fits
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Evidence Context
This study contributes evidence to Exercise therapy, Synchronous online type 1 diabetes psychoeducational program for school staff and HbA1c, Improvement in contrast sensitivity in the left eye, Improvement in contrast sensitivity in the right eye.
This study contributes evidence to
Primary intervention
Exercise therapy
Primary outcomes
- HbA1c
- Improvement in contrast sensitivity in the left eye
- Improvement in contrast sensitivity in the right eye
Primary intervention
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
4
Evidence pairs
371
Related studies
Why it is useful
- Contributes to 4 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence relationship
Diabetes Self-Management Education and Support (DSMES) Programs and HbA1c
Related evidence
Evidence topic
HbA1c Reduction
Save evidence
Evidence topic
Diabetes Self-Management Education and Support
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Improvement in contrast sensitivity in the left eye
Exercise therapy → Improvement in contrast sensitivity in the left eye
Exercise therapy → Improvement in contrast sensitivity in the left eye
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Improvement in contrast sensitivity in the right eye
Exercise therapy → Improvement in contrast sensitivity in the right eye
Exercise therapy → Improvement in contrast sensitivity in the right eye
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
HbA1c
Synchronous online type 1 diabetes psychoeducational program for school staff → HbA1c
Synchronous online type 1 diabetes psychoeducational program for school staff → HbA1c
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Evidence Library
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Evidence Suggest
- Device-measured physical activity led to a significant 1.18% decrease in HbA1c.
- Control group showed a smaller reduction in HbA1c of -0.57%.
- Contrast sensitivity improvements were noted but lacked statistical significance.
Who this applies to
- Individuals newly diagnosed with AGT.
- Patients in Ghana seeking lifestyle interventions for diabetes management.
Keep in Mind
- Findings may not be applicable to populations outside Ghana.
- The study's small sample size may affect the reliability of the results.
- Further research is needed to confirm the effectiveness of the interventions.
Between the Lines
- The study had a small sample size, limiting generalizability.
- Effectiveness of the general health education intervention remains unclear.
- Statistical significance for contrast sensitivity improvements was not established.
Evidence Library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Exercise therapy and HbA1c, Exercise therapy and Improvement in contrast sensitivity in the left eye.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Exercise therapy → HbA1c
Physical Activity
- EvidenceScore™
- 81
- Strong
- ImpactScore™
- 79
- Positive
- ConsistencyScore™
- 86
- consistent
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Included in these evidence collections
Curated evidence collections and hubs this study is part of.
Exercise therapy Evidence Hub
All studies on Exercise therapy
Contributes to Exercise therapy evidence base.
HbA1c Evidence Hub
All studies measuring HbA1c
Measures HbA1c as a key outcome.
Improvement in contrast sensitivity in the left eye Evidence Hub
All studies measuring Improvement in contrast sensitivity in the left eye
Measures Improvement in contrast sensitivity in the left eye as a key outcome.
Recent Diabetes Research
Latest published studies
Published within the last 2 years.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Exercise therapy and HbA1c
7 results
All studies on Exercise therapy and Improvement in contrast sensitivity in the left eye
1 results
All studies on Exercise therapy
7 results
All studies measuring HbA1c
7 results
All studies measuring Improvement in contrast sensitivity in the left eye
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Diabetes Self-Management Education and Support (DSMES) Programs improve HbA1c?
Diabetes Self-Management Education and Support (DSMES) Programs may improve HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 32 supporting studies with generally consistent results and a positive effect signal.
Limitations
- Population details are unavailable.
Does Exercise therapy improve HbA1c?
Exercise therapy may improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 81.3 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does Exercise therapy improve improvement in contrast sensitivity in the left eye?
Exercise therapy appears to improve Improvement in contrast sensitivity in the left eye.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Improvement in contrast sensitivity in the left eye
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Exercise therapy improve improvement in contrast sensitivity in the right eye?
Exercise therapy appears to improve Improvement in contrast sensitivity in the right eye.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Improvement in contrast sensitivity in the right eye
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
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