Last updated August 24, 2026
Key finding
Decreased postprandial concentrations of oxidised glutathione (p < 0.001)
Comparison of a vegan meal and a conventional meat-containing meal in adults with type 2 diabetes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
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Study focus
Comparison of a vegan meal and a conventional meat-containing meal in adults with type 2 diabetes.
This study evaluated Comparison of a vegan meal and a conventional meat-containing meal in adults with type 2 diabetes.
Limitations were not clearly described in the extracted text.
Published in
Publication details and source links for this paper.
Hana M, Marta K, Michaela K, et al. The effects of a plant-based meal on postprandial oxidative and dicarbonyl stress in type 2 diabetes: a randomized crossover study. Nutrition & Metabolism. 2021;18:84. doi:10.1186/s12986-021-00609-5
Evidence network
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This study contributes evidence to Processed meat and cheese meal (M-meal), Vegan meal (V-meal) and Postprandial concentrations of methylglyoxal, Decrease in predicted exchange flux of L-asparagine, Glutathione peroxidase (GPx), and 5 more.
This study contributes evidence to
Primary intervention
Processed meat and cheese meal (M-meal)
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
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0
Related topics
8
Evidence pairs
0
Related studies
Core evidence
The primary outcomes reported in this study.
Processed meat and cheese meal (M-meal) → Postprandial concentrations of methylglyoxal
Processed meat and cheese meal (M-meal) → Postprandial concentrations of methylglyoxal
Vegan meal (V-meal) → Decrease in predicted exchange flux of L-asparagine
Vegan meal (V-meal) → Decrease in predicted exchange flux of L-asparagine
Vegan meal (V-meal) → Glutathione peroxidase (GPx)
Vegan meal (V-meal) → Glutathione peroxidase (GPx)
Vegan meal (V-meal) → Mean leptin level change
Vegan meal (V-meal) → Mean leptin level change
Vegan meal (V-meal) → Postprandial ghrelin secretion
Vegan meal (V-meal) → Postprandial ghrelin secretion
Vegan meal (V-meal) → Postprandial GLP-1 Secretion Increase in T2D
Vegan meal (V-meal) → Postprandial GLP-1 Secretion Increase in T2D
Vegan meal (V-meal) → Ultrasound Grading of Hepatic Steatosis
Vegan meal (V-meal) → Ultrasound Grading of Hepatic Steatosis
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Vegan meal (V-meal) and Postprandial GLP-1 Secretion Increase in T2D, Processed meat and cheese meal (M-meal) and Postprandial concentrations of methylglyoxal.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Postprandial GLP-1 Secretion Increase in T2D
Measures Postprandial GLP-1 Secretion Increase in T2D as a key outcome.
All studies on Vegan meal (V-meal)
Contributes to Vegan meal (V-meal) evidence base.
All studies measuring Postprandial concentrations of methylglyoxal
Measures Postprandial concentrations of methylglyoxal as a key outcome.
All studies on Processed meat and cheese meal (M-meal)
Contributes to Processed meat and cheese meal (M-meal) evidence base.
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2 results
1 results
2 results
1 results
2 results
Generated from the study's connected evidence using Evidence Intelligence™.
Vegan meal (V-meal) may improve postprandial glp-1 secretion increase in t2d.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
Postprandial GLP-1 Secretion Increase in T2D
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
Processed meat and cheese meal (M-meal) appears to improve postprandial concentrations of methylglyoxal.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Postprandial concentrations of methylglyoxal
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Vegan meal (V-meal) appears to improve decrease in predicted exchange flux of l-asparagine.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Decrease in predicted exchange flux of L-asparagine
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Vegan meal (V-meal) appears to improve glutathione peroxidase (GPX).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Glutathione peroxidase (GPx)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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