Research Summary
Analyzed using Evidence Intelligence™

Vegan meals improve insulin secretion in type 2 diabetes

Last updated August 24, 2026

Key finding

An increase in the stimulated secretion of insulin (by 30.5%; 95% CI 21.2 to 40.7%; p < 0.001) was observed following consumption of the V-meal.

This study compared the effects of vegan and meat meals on insulin and incretin secretion in individuals with type 2 diabetes, finding significant increases in insulin and incretin levels after the vegan meal.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study compared the effects of vegan and meat meals on insulin and incretin secretion in individuals with type 2 diabetes, finding significant increases in insulin and incretin levels after the vegan meal.

Clinical relevance

These findings suggest that dietary choices, particularly the inclusion of vegan meals, may enhance insulin and incretin responses in individuals with type 2 diabetes. This could have implications for dietary recommendations aimed at improving glycemic control and overall metabolic health in this population.

Keep in mind

The study's sample size and demographic characteristics may limit generalizability. Only two types of meals were tested, which may not represent all dietary patterns. Long-term effects of meal type on diabetes management were not assessed.

Published in

Journal Reference

Publication details and source links for this paper.

Hana K, Andrea T, Marta K, et al. Effects of Vegan vs. Meat Meals on Postprandial Incretin and Insulin Secretion in Type 2 Diabetes. Nutrients. 2019;11(3):486. doi:10.3390/nu11030486

Main Effects

An increase in stimulated insulin secretion by 30.5% (p < 0.001) was observed after the V-meal.

Stimulated GLP-1 secretion increased by 19.2% (p < 0.001) following the V-meal.

A decrease in GIP secretion by -9.4% (p = 0.02) was noted after the V-meal.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Processed hamburger meat meal (M-meal), Vegan meal (V-meal) and Glucose iAUC (OGTT), Insulin resistance, PREDIM (predicted clamp-derived insulin sensitivity index), and 6 more.

Primary intervention

Processed hamburger meat meal (M-meal)

Primary outcomes

  • Glucose iAUC (OGTT)
  • Insulin resistance
  • PREDIM (predicted clamp-derived insulin sensitivity index)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

9
Evidence pairs
9
Relationships
4
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

4

Related topics

9

Evidence pairs

717

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 9 evidence relationships
  • Includes primary outcome data
  • Linked to 4 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence topic

Beta-Cell Function

matched_outcome

Related evidence

Evidence topic

C-Peptide

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Glucose iAUC (OGTT)

Processed hamburger meat meal (M-meal) → Glucose iAUC (OGTT)

Processed hamburger meat meal (M-meal) → Glucose iAUC (OGTT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Insulin resistance

Processed hamburger meat meal (M-meal) → Insulin resistance

Processed hamburger meat meal (M-meal) → Insulin resistance

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

PREDIM (predicted clamp-derived insulin sensitivity index)

Processed hamburger meat meal (M-meal) → PREDIM (predicted clamp-derived insulin sensitivity index)

Processed hamburger meat meal (M-meal) → PREDIM (predicted clamp-derived insulin sensitivity index)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Beta-cell function

Vegan meal (V-meal) → Beta-cell function

Vegan meal (V-meal) → Beta-cell function

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

C-peptide

Vegan meal (V-meal) → C-peptide

Vegan meal (V-meal) → C-peptide

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Insulin secretion levels after Roux-en-Y gastric bypass surgery

Vegan meal (V-meal) → Insulin secretion levels after Roux-en-Y gastric bypass surgery

Vegan meal (V-meal) → Insulin secretion levels after Roux-en-Y gastric bypass surgery

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Postprandial GLP-1 Secretion Increase in T2D

Vegan meal (V-meal) → Postprandial GLP-1 Secretion Increase in T2D

Vegan meal (V-meal) → Postprandial GLP-1 Secretion Increase in T2D

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Postprandial secretion of amylin in T2D

Vegan meal (V-meal) → Postprandial secretion of amylin in T2D

Vegan meal (V-meal) → Postprandial secretion of amylin in T2D

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Total costs in telemedicine group compared to standard care

Vegan meal (V-meal) → Total costs in telemedicine group compared to standard care

Vegan meal (V-meal) → Total costs in telemedicine group compared to standard care

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Vegan meals significantly increased insulin secretion by 30.5%.
  • C-peptide secretion rose by 7.1% after the vegan meal.
  • GLP-1 secretion increased by 19.2% following the vegan meal.
who this applies

Who this applies to

  • Adults diagnosed with type 2 diabetes.
  • Individuals interested in dietary interventions for diabetes management.
keep in mind

Keep in Mind

  • Results may not apply to all dietary patterns beyond vegan and meat meals.
  • The study did not evaluate long-term dietary adherence or health outcomes.
  • Further research is needed to explore the effects of different meal compositions.
between the lines

Between the Lines

  • The study's sample size and demographic characteristics may limit generalizability.
  • Only two types of meals were tested, which may not represent all dietary patterns.
  • Long-term effects of meal type on diabetes management were not assessed.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Vegan meal (V-meal) and Postprandial GLP-1 Secretion Increase in T2D, Processed hamburger meat meal (M-meal) and Postprandial and OGTT Glucose.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Included in these evidence collections

Curated evidence collections and hubs this study is part of.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

What evidence is available on Vegan meal (V-meal) and postprandial glp-1 secretion increase in t2d?

Moderate Evidence

Vegan meal (V-meal) may improve postprandial glp-1 secretion increase in t2d.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Postprandial GLP-1 Secretion Increase in T2D

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Vegan meal (V-meal) improve c-peptide?

Emerging Evidence

Vegan meal (V-meal) appears to improve c-peptide.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    C-peptide

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Vegan meal (V-meal) improve insulin secretion levels after roux-en-y gastric bypass surgery?

Emerging Evidence

Vegan meal (V-meal) appears to improve insulin secretion levels after roux-en-y gastric bypass surgery.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Insulin secretion levels after Roux-en-Y gastric bypass surgery

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Vegan meal (V-meal) improve postprandial secretion of amylin in t2d?

Emerging Evidence

Vegan meal (V-meal) appears to improve postprandial secretion of amylin in t2d.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Postprandial secretion of amylin in T2D

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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