Last updated September 12, 2026
Key finding
The patient has been in complete remission for 6 years.
This study reports a case of a 6-year complete remission of type 1 diabetes in an adult following specific interventions.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study reports a case of a 6-year complete remission of type 1 diabetes in an adult following specific interventions.
Achieving remission in type 1 diabetes is a significant clinical milestone, as it can reduce the burden of daily insulin administration and improve quality of life. This case suggests that a multifaceted approach involving medication, diet, and exercise may offer new avenues for managing type 1 diabetes effectively.
The study involved a single participant, limiting generalizability. Effectiveness of interventions remains unclear due to lack of comparative data. Long-term sustainability of remission is uncertain. No control group was established for comparison.
Published in
Publication details and source links for this paper.
Alexander M, John RA, Vânia BS, Maria TP. A case of 6-year complete remission of type 1 diabetes in an adult. Cureus. 2023;15(1):e34376. doi:10.7759/cureus.34376
The patient achieved complete remission of type 1 diabetes for 6 years.
Insulin requirements significantly reduced after the intervention.
Glycemic control improved due to the combination of interventions.
Serum DDP-4 levels were noted to be upregulated in type 1 diabetes.
Evidence network
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This study contributes evidence to Low-carbohydrate diet, Sitagliptin 100 mg daily and Reduced insulin requirements after surgery, Diabetes remission, Serum DDP-4.
This study contributes evidence to
Primary intervention
Low-carbohydrate diet
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
3
Evidence pairs
21
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Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Core evidence
The primary outcomes reported in this study.
Low-carbohydrate diet → Reduced insulin requirements after surgery
Low-carbohydrate diet → Reduced insulin requirements after surgery
Sitagliptin 100 mg daily → Diabetes remission
Sitagliptin 100 mg daily → Diabetes remission
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Low-Carbohydrate Diet Education and Diabetes Remission.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Diabetes Remission
Measures Diabetes Remission as a key outcome.
All studies on Low-Carbohydrate Diet Education
Contributes to Low-Carbohydrate Diet Education evidence base.
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Generated from the study's connected evidence using Evidence Intelligence™.
Low-carbohydrate diet appears to improve reduced insulin requirements after surgery.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Reduced insulin requirements after surgery
EvidenceScore™ Unknown | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Sitagliptin 100 mg daily appears to improve diabetes remission.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Diabetes remission
EvidenceScore™ Unknown | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Sitagliptin 100 mg daily for serum ddp-4.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Serum DDP-4
EvidenceScore™ Unknown | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
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