Research Summary
Analyzed using Evidence Intelligence™

Smart insulin software improves glycemic control in T2DM patients.

Last updated July 12, 2026

Key finding

Mean CBG before dinner was 10.07 (8.70, 11.60) vs 11.42 (9.89, 14.86), P = 0.006.

This study evaluated the effectiveness of smart insulin dosage software versus traditional physician experience in managing hyperglycemia in T2DM patients receiving insulin treatment, finding significant advantages for the software.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

High Risk

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the effectiveness of smart insulin dosage software versus traditional physician experience in managing hyperglycemia in T2DM patients receiving insulin treatment, finding significant advantages for the software.

Clinical relevance

Effective management of blood glucose levels is crucial for individuals with T2DM to prevent complications. This study highlights the potential of technology, specifically smart insulin dosage software, to enhance diabetes management, offering a promising alternative to traditional methods that may not be as effective.

Keep in mind

The study may have limited generalizability due to specific population characteristics. Sample size and demographic diversity were not detailed. Potential biases in self-reported data were not addressed.

Published in

Journal Reference

Publication details and source links for this paper.

Lihua Z, Chenwei W, Chunhong W, et al. Among T2DM receiving insulin treatment, the smart insulin dosage software with trend arrows has more advantage on controlling hyperglycemia than the physician’s experience. Endocrine. 2026;91(1):86. doi:10.1007/s12020-025-04509-z

Main Effects

Mean capillary blood glucose before dinner decreased by 1.35 mmol/L (P = 0.006).

Mean glucose from rtCGM decreased by 1.44 mmol/L (P = 0.003).

Time in range increased by 17% (P = 0.001).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Smart insulin dosage software (App group) and Blood glucose, Glycemia risk index, Incidence of hypoglycemia, and 4 more.

Primary intervention

Smart insulin dosage software (App group)

Primary outcomes

  • Blood glucose
  • Glycemia risk index
  • Incidence of hypoglycemia

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
1
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 63

1

Related topics

7

Evidence pairs

171

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 1 direct semantic evidence topic

Topic contributions

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence topic

Glycemic Control

matched_outcome

Core evidence

Study findings

The primary outcomes reported in this study.

Blood glucose

Smart insulin dosage software (App group) → Blood glucose

Smart insulin dosage software (App group) → Blood glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Glycemia risk index

Smart insulin dosage software (App group) → Glycemia risk index

Smart insulin dosage software (App group) → Glycemia risk index

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Incidence of hypoglycemia

Smart insulin dosage software (App group) → Incidence of hypoglycemia

Smart insulin dosage software (App group) → Incidence of hypoglycemia

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Mean glucose from rtCGM

Smart insulin dosage software (App group) → Mean glucose from rtCGM

Smart insulin dosage software (App group) → Mean glucose from rtCGM

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Time above range

Smart insulin dosage software (App group) → Time above range

Smart insulin dosage software (App group) → Time above range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Time below range

Smart insulin dosage software (App group) → Time below range

Smart insulin dosage software (App group) → Time below range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Time in range

Smart insulin dosage software (App group) → Time in range

Smart insulin dosage software (App group) → Time in range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Smart insulin software reduced mean capillary blood glucose before dinner by 1.35 mmol/L.
  • Participants using the app had a 17% increase in time spent in the target glucose range.
  • Mean glucose from rtCGM was 1.44 mmol/L lower in the app group.
who this applies

Who this applies to

  • Adults diagnosed with type 2 diabetes mellitus.
  • Patients currently receiving insulin treatment.
keep in mind

Keep in Mind

  • Results may not apply to all populations with diabetes.
  • Further studies are needed to confirm long-term effectiveness.
  • The study did not assess all potential confounding factors.
between the lines

Between the Lines

  • The study may have limited generalizability due to specific population characteristics.
  • Sample size and demographic diversity were not detailed.
  • Potential biases in self-reported data were not addressed.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Smart insulin dosage software (App group) and Fasting Glucose, Smart insulin dosage software (App group) and CGM Time in Range.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Smart insulin dosage software (App group) improve blood glucose?

Emerging Evidence

Smart insulin dosage software (App group) appears to improve Blood glucose.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Blood glucose

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Smart insulin dosage software (App group) improve mean glucose from rtcgm?

Emerging Evidence

Smart insulin dosage software (App group) appears to improve Mean glucose from rtCGM.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Mean glucose from rtCGM

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Smart insulin dosage software (App group) improve time above range?

Emerging Evidence

Smart insulin dosage software (App group) appears to improve Time above range.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Time above range

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Smart insulin dosage software (App group) improve time in range?

Emerging Evidence

Smart insulin dosage software (App group) appears to improve Time in range.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Time in range

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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