Research Summary
Analyzed using Evidence Intelligence™

Super Bolus Improves Glycemic Control in Children with Type 1 Diabetes

Last updated September 11, 2026

Key finding

The SB group had lower glucose levels 154 ± 37.4 mg/dL compared to 177 ± 49.2 mg/dL in the NB group, p < 0.001.

Super bolus compared to normal bolus for high glycemic index meals in children with type 1 diabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Extended (5–20+ y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

Super bolus compared to normal bolus for high glycemic index meals in children with type 1 diabetes.

Clinical relevance

This study evaluated Super bolus compared to normal bolus for high glycemic index meals in children with type 1 diabetes.

Keep in mind

Limitations were not clearly described in the extracted text.

Published in

Journal Reference

Publication details and source links for this paper.

Emilia K, Magdalena D, Agnieszka S, Andrea F. Super Bolus versus Normal Bolus for High Glycemic Index Meals in Children with Type 1 Diabetes: A Randomized Controlled Trial. Nutrients. 2024;16(2):263. doi:10.3390/nu16020263

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Normal Bolus, Super Bolus and Blood glucose, Glucose iAUC (OGTT), Maximum Glycemic Rise, and 4 more.

Primary intervention

Normal Bolus

Primary outcomes

  • Blood glucose
  • Glucose iAUC (OGTT)
  • Maximum Glycemic Rise

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

8
Evidence pairs
8
Relationships
5
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

5

Related topics

8

Evidence pairs

1206

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 8 evidence relationships
  • Includes primary outcome data
  • Linked to 5 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

Glycemic Control

matched_outcome

Related evidence

Evidence topic

Fasting Blood Glucose

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Blood glucose

Normal Bolus → Blood glucose

Normal Bolus → Blood glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Blood glucose

Super Bolus → Blood glucose

Super Bolus → Blood glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Glucose iAUC (OGTT)

Super Bolus → Glucose iAUC (OGTT)

Super Bolus → Glucose iAUC (OGTT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Maximum Glycemic Rise

Super Bolus → Maximum Glycemic Rise

Super Bolus → Maximum Glycemic Rise

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Mean amplitude of glycemic excursions (MAGE)

Super Bolus → Mean amplitude of glycemic excursions (MAGE)

Super Bolus → Mean amplitude of glycemic excursions (MAGE)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Number of hypoglycaemic episodes

Super Bolus → Number of hypoglycaemic episodes

Super Bolus → Number of hypoglycaemic episodes

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Peak insulin levels during oral glucose tolerance test (OGTT)

Super Bolus → Peak insulin levels during oral glucose tolerance test (OGTT)

Super Bolus → Peak insulin levels during oral glucose tolerance test (OGTT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Time in range

Super Bolus → Time in range

Super Bolus → Time in range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Normal Bolus and Fasting Glucose, Super Bolus and Fasting Glucose.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Normal Bolus improve blood glucose?

Emerging Evidence

Normal Bolus appears to improve blood glucose.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Blood glucose

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Super Bolus improve blood glucose?

Emerging Evidence

Super Bolus appears to improve blood glucose.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Blood glucose

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Super Bolus improve glucose iauc (OGTT)?

Emerging Evidence

Super Bolus appears to improve glucose iauc (OGTT).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Glucose iAUC (OGTT)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Super Bolus improve maximum glycemic rise?

Emerging Evidence

Super Bolus appears to improve maximum glycemic rise.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Maximum Glycemic Rise

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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