Last updated September 1, 2026
Key finding
The iAUC for plasma glucose was significantly lower after the consumption of WD (WD: 3551 ± 546; BC: 9610 ± 848 mg min/dl; P < 0.01)
This study evaluated the impact of a whey protein-based nutritional drink on glycaemic responses in type 2 diabetes patients, finding significant differences in glucose and GLP-1 levels compared to boiled rice with chicken.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
Save research, organize studies, and quickly find important evidence again.
Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the impact of a whey protein-based nutritional drink on glycaemic responses in type 2 diabetes patients, finding significant differences in glucose and GLP-1 levels compared to boiled rice with chicken.
These findings are significant as they suggest that incorporating a whey protein-based nutritional drink into the diet of patients with type 2 diabetes may improve glycaemic control, potentially leading to better management of the condition and reducing the risk of complications associated with high blood sugar levels.
The study's sample size and demographic diversity were not specified. The long-term effects of the nutritional drink were not assessed. The study did not explore the impact of other dietary factors.
Published in
Publication details and source links for this paper.
Pimnapanut S, Aree P, Kemika P, Siriporn T, Wantanee K. The effect of a whey protein-based multi-ingredient nutritional drink on postprandial glycaemic responses in patients with type 2 diabetes mellitus: a randomized controlled trial. Journal of Nutritional Science. 2021;10:e49. doi:10.1017/jns.2021.41
The iAUC for plasma glucose was significantly lower after the consumption of the whey protein drink (3551 ± 546 mg min/dl) compared to the rice and chicken meal (9610 ± 848 mg min/dl; P < 0.01).
The iAUC for active GLP-1 was significantly higher after the consumption of the whey protein drink (2230 ± 441 pM min/ml) compared to the rice and chicken meal (925 ± 183 pM min/ml; P < 0.01).
The iAUC for plasma glucose was significantly higher after the consumption of the rice and chicken meal compared to the whey protein drink.
The iAUC for active GLP-1 was significantly lower after the consumption of the rice and chicken meal compared to the whey protein drink.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Boiled white rice with chicken, whey protein 20g and Glucose iAUC (OGTT), Incremental area under the curve for active GLP-1 (iAUC 0–240 min).
This study contributes evidence to
Primary intervention
Boiled white rice with chicken
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
4
Evidence pairs
661
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Save studies and evidence pages, organize your personal Evidence Tracker, and keep the research you care about in one place.
Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Boiled white rice with chicken → Glucose iAUC (OGTT)
Boiled white rice with chicken → Glucose iAUC (OGTT)
Boiled white rice with chicken → Incremental area under the curve for active GLP-1 (iAUC 0–240 min)
Boiled white rice with chicken → Incremental area under the curve for active GLP-1 (iAUC 0–240 min)
whey protein 20g → Incremental area under the curve for active GLP-1 (iAUC 0–240 min)
whey protein 20g → Incremental area under the curve for active GLP-1 (iAUC 0–240 min)
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on whey protein 20g and Postprandial and OGTT Glucose, whey protein 20g and Incremental area under the curve for active GLP-1 (iAUC 0–240 min).
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Postprandial and OGTT Glucose
Measures Postprandial and OGTT Glucose as a key outcome.
All studies on whey protein 20g
Contributes to whey protein 20g evidence base.
All studies measuring Incremental area under the curve for active GLP-1 (iAUC 0–240 min)
Measures Incremental area under the curve for active GLP-1 (iAUC 0–240 min) as a key outcome.
Jump to pre-filtered views in Evidence Explorer.
3 results
1 results
3 results
3 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
whey protein 20g appears to improve glucose iauc (OGTT).
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Strong | EvidenceScore™ 78.6 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Boiled white rice with chicken for glucose iauc (OGTT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Boiled white rice with chicken for incremental area under the curve for active glp-1 (iauc 0–240 min).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Incremental area under the curve for active GLP-1 (iAUC 0–240 min)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
whey protein 20g may worsen incremental area under the curve for active glp-1 (iauc 0–240 min) or be associated with harm.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Incremental area under the curve for active GLP-1 (iAUC 0–240 min)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | moderate negative | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Follow the topics this study contributes to.
Open broader Evidence Explorer views for this relationship.
Read related research summaries.
Focused on evidence, not advertising.
Your data is always protected.
New studies added every day.
