Clinical evidence dossier
Non-surgical periodontal treatment
HbA1c
Evidence signal
Evidence signal
Strong
This is an authoritative evidence signal supplied by Clinical Reference. It is not a formal clinical grade, treatment recommendation, or pooled effect estimate.
Evidence snapshot
- Authoritative support records
- 14
- Supporting studies available for review
- 14
- Randomized trials
- 10
- Reported effects
- 14
Clinical conclusion
Non-surgical periodontal treatment shows a moderate positive evidence signal for improving HbA1c across the studied comparisons.
The conclusion and evidence-signal classification are distinct authoritative fields and are reproduced as published.
Observed effects
Observed study estimates; not a pooled treatment effect.
Change from baseline
Absolute change
−1.1% to −0.2%
Between-group effect
Absolute change
−0.7% to −0.7%
Change from baseline
Mean difference
−0.13 % HbA1c to −0.13 % HbA1c
Change from baseline
Mean difference
−0.5% to 0.45%
Between-group effect
Mean difference
−0.12% to 0%
Evidence composition
- Non-randomized studies
- 0
- Other designs
- 0
- Unresolved designs
- 4
- Magnitude-eligible effects
- 11
Consistency
Consistency classification
Mixed
- Positive
- 7
- No effect
- 6
- Mixed
- 1
- Negative
- 0
Population and applicability
Structured population data were available for 14 of 14 supporting studies. 12 studies described participants with type 2 diabetes. 13 studies described adult participants.
This population information refers to the materialized supporting studies available for review. Omitted support records remain part of the authoritative support accounting and are available through the audit experience.
View reported population descriptions
These descriptions are reported across the supporting studies; they are not a single synthesized population.
- Adults diagnosed with type 2 diabetes.
- Individuals experiencing periodontal disease.
- Individuals seeking weight loss through dietary interventions.
- Patients with chronic kidney disease
- Individuals undergoing treatment for periodontal disease
- Adults with chronic periodontitis
- Patients with well-controlled type II diabetes
- Patients undergoing non-surgical periodontal treatment.
- Individuals interested in the relationship between oral health and diabetes management.
- Adults aged 30-70 with type 2 diabetes.
- Patients diagnosed with chronic periodontitis.
- Adults with Type 2 Diabetes Mellitus.
Limitations
- Upstream consistency scoring indicates mixed findings across the evidence.
- 3 supporting studies do not have a displayable topic-matched quantitative effect.
- Evidence uses heterogeneous comparison contexts: active_comparator, baseline_within_group, usual_care.
- 4 supporting studies have high, serious, critical, unclear, or unavailable risk-of-bias information.
- 1 study contains conflicting p-value and significance fields; those significance claims are suppressed.
Supporting evidence
Inspect the authoritative studies and omitted support records for this dossier.