Clinical evidence dossier
High-intensity interval exercise
HbA1c
Evidence signal
Evidence signal
Strong
This is an authoritative evidence signal supplied by Clinical Reference. It is not a formal clinical grade, treatment recommendation, or pooled effect estimate.
Evidence snapshot
- Authoritative support records
- 5
- Supporting studies available for review
- 5
- Randomized trials
- 4
- Reported effects
- 7
Clinical conclusion
High-intensity interval exercise shows a strong positive evidence signal for improving HbA1c across the studied comparisons.
Observed effects
Observed study estimates; not a pooled treatment effect.
Change from baseline
Mean difference
−1.11% to −0.5%
Between-group effect
Mean difference
−3.35% to −0.7%
Evidence composition
- Non-randomized studies
- 0
- Other designs
- 0
- Unresolved designs
- 1
- Magnitude-eligible effects
- 7
Consistency
Consistency classification
Consistent
- Positive
- 4
- No effect
- 1
- Mixed
- 0
- Negative
- 0
Population and applicability
Structured population data were available for 5 of 5 supporting studies. 5 studies described participants with type 2 diabetes. 5 studies described adult participants.
This population information refers to the materialized supporting studies available for review. Omitted support records remain part of the authoritative support accounting and are available through the audit experience.
View reported population descriptions
These descriptions are reported across the supporting studies; they are not a single synthesized population.
- Adults aged 18-65 with type 2 diabetes.
- Individuals looking for effective exercise interventions to manage diabetes.
- Adults diagnosed with diabetic peripheral neuropathy.
- Patients with type 2 diabetes experiencing complications.
- Individuals seeking alternative exercise regimens for metabolic health.
- Adults diagnosed with type 2 diabetes.
- Individuals seeking effective exercise interventions for diabetes management.
- Adults diagnosed with Type 2 Diabetes.
- Individuals seeking to improve cardiovascular health.
- Patients with stable health conditions allowing for physical activity.
- Adults aged 30-65 with type 2 diabetes.
- Individuals seeking to improve glycaemic control through exercise.
Limitations
- 1 supporting study does not have a displayable topic-matched quantitative effect.
- Evidence uses heterogeneous comparison contexts: other, unknown_unresolved, usual_care.
- 1 supporting study has high, serious, critical, unclear, or unavailable risk-of-bias information.
Supporting evidence
Inspect the authoritative studies and omitted support records for this dossier.