Weight & Anthropometrics

Evidence Snapshot

Evidence relationships

Studies reviewed

Interventions evaluated

Strongest evidence area

Semaglutide

Top Evidence Areas

Rank	Intervention	Outcome	Effectiveness	Strength	Consistency	Studies
#1	Behavioral lifestyle interventions	BMI	Moderate Positive	Limited	Unclear	1
#2	Behavioral lifestyle interventions	Body weight	Moderate Positive	Limited	Unclear	1
#3	Basal insulin	Body weight	Moderate Negative	Weak	Unclear	1
#4	Behavioral counseling	Body weight	Moderate Positive	Weak	Unclear	1
#5	Boscisucrophage	Body weight	Moderate Positive	Limited	Unclear	1
#6	Calorie restriction	Body weight	Moderate Positive	Limited	Unclear	1
#7	Curcumin plus piperine	BMI	Moderate Positive	Limited	Unclear	1
#8	Curcumin plus piperine	Waist circumference	Moderate Positive	Limited	Unclear	1
#9	Dapagliflozin	Body weight	Moderate Positive	Limited	Unclear	1
#10	Del Immune V Extra bacterial lysate	BMI	Neutral	Weak	Unclear	1

Rank #1

BMI

Behavioral lifestyle interventions

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Rank #2

Body weight

Behavioral lifestyle interventions

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Rank #3

Body weight

Basal insulin

Effectiveness

Moderate Negative

Strength

Weak

Consistency

Unclear

Studies

Rank #4

Body weight

Behavioral counseling

Effectiveness

Moderate Positive

Strength

Weak

Consistency

Unclear

Studies

Rank #5

Body weight

Boscisucrophage

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Rank #6

Body weight

Calorie restriction

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Rank #7

BMI

Curcumin plus piperine

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Rank #8

Waist circumference

Curcumin plus piperine

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Rank #9

Body weight

Dapagliflozin

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Rank #10

BMI

Del Immune V Extra bacterial lysate

Effectiveness

Neutral

Strength

Weak

Consistency

Unclear

Studies

Practical Questions

Which interventions are most often studied for Weight & Anthropometrics?

most studied

Based on 9 evidence relationships across 10 studies

Outcomes:

BMIBody weightWaist circumferenceBody fat mass

Interventions:

Del Immune V Extra bacterial lysateLow Carbohydrate dietMediterranean ketogenic diet

Which interventions need more research for Weight & Anthropometrics?

research gaps

Based on 3 evidence relationships across 6 studies

Outcomes:

Body weightBMI

Interventions:

Low Carbohydrate dietMultidisciplinary lifestyle intervention for type 2 diabetes remission

How does Semaglutide compare with Dapagliflozin for Weight & Anthropometrics?

compare

Based on 2 evidence relationships across 3 studies

Outcomes:

Body weight

Interventions:

DapagliflozinSemaglutide

Evidence Landscape

Evidence landscape

Each bubble represents an evidence relationship. Position shows effectiveness and strength; size reflects study volume.

Limited evidence

Promising

Reliable

High impact

Lower Evidence Strength→Higher Evidence Strength

Lower Effectiveness→Higher Effectiveness

Explore by Intervention

Intervention	Pairs	Research	Avg Strength
Low Carbohydrate diet	3	2	47
Multidisciplinary lifestyle intervention for type 2 diabetes remission	2	2	46
Semaglutide	2	2	53
Tirzepatide	2	2	49
Basal insulin	1	1	26
Behavioral counseling	1	1	38
Behavioral lifestyle interventions	2	1	45
Boscisucrophage	1	1	41
Calorie restriction	1	1	46
Curcumin plus piperine	2	1	44
Dapagliflozin	1	1	53
Del Immune V Extra bacterial lysate	3	1	37
Digital physician Pharmacist collaborative care	2	1	47
Dulaglutide dose escalation	1	1	46
Exercise therapy	1	1	34
GLP 1 receptor agonists	1	1	47
Insulin Glargine Lixisenatide dosis	2	1	45
Liraglutide	1	1	53
Mediterranean ketogenic diet	3	1	43
Metformin	1	1	53
Pioglitazone	1	1	32
Probiotics	2	1	38
Remote nutrition education on low Carbohydrate diet	2	1	44
Telemonitoring	1	1	35
Telephone counseling	1	1	45
Very Low Calorie ketogenic diet	3	1	43

Latest Research

L. rhamnosus bacterial lysate may improve HbA1c in type 2 diabetes

Study Type: randomized-controlled-trials-rctsPublished: May 30, 2026

int-del-immune-v-extra-bacterial-lysate

out-bmiout-body-weight

Switching to tirzepatide from dulaglutide improved HbA1c and weight across baseline characteristics

Study Type: randomized-controlled-trials-rctsPublished: May 30, 2026

int-dulaglutide-dose-escalationint-tirzepatide

out-body-weight

Elderly patient with long-standing diabetes achieved sustained insulin independence through lifestyle intervention

Study Type: non-randomized-clinical-trial-non-rctPublished: May 29, 2026

int-multidisciplinary-lifestyle-intervention-for-type-2-diabetes

out-bmiout-body-weight

Intensive lifestyle program was linked to diabetes remission in Indian adults

Study Type: non-randomized-clinical-trial-non-rctPublished: May 29, 2026

int-multidisciplinary-lifestyle-intervention-for-type-2-diabetes

out-bmiout-body-weight

Digital pharmacist-physician care improves HbA1c in type 2 diabetes

Study Type: randomized-controlled-trials-rctsPublished: May 29, 2026

int-digital-physician-pharmacist-collaborative-care

out-waist-circumferenceout-waist-to-hip-ratio

Mediterranean ketogenic eating matched VLCKD for weight loss over 3 months

Study Type: non-randomized-clinical-trial-non-rctPublished: May 27, 2026

int-mediterranean-ketogenic-dietint-very-low-calorie-ketogenic-diet

out-bmiout-body-weight

Remote low-carb diet education reduces HbA1c by 0.91% and cuts medication use in half for type 2 diabetes

Study Type: randomized-controlled-trials-rctsPublished: May 27, 2026

int-remote-nutrition-education-low-carb

out-bmiout-body-weight

Lifestyle calorie-carbohydrate plans improved type 2 diabetes remission versus usual care

Study Type: randomized-controlled-trials-rctsPublished: May 26, 2026

int-calorie-restrictionint-low-carbohydrate-diet

out-body-fat-massout-body-weight

Curcumin plus piperine may improve sleep and mood in diabetic retinopathy

Study Type: randomized-controlled-trials-rctsPublished: May 26, 2026

int-curcumin-plus-piperine

out-bmiout-waist-circumference

Lifestyle changes plus probiotic use were linked with better HbA1c in one man with type 2 diabetes

Study Type: non-randomized-clinical-trial-non-rctPublished: May 26, 2026

int-behavioral-counselingint-probiotics

out-body-fat-massout-body-weight

Full Evidence Table

Showing 43 of 43 evidence pairs

Intervention	Outcome	Effectiveness	Strength	Consistency	Studies
Behavioral lifestyle interventions	BMI	Moderate Positive	Limited	Unclear	1
Behavioral lifestyle interventions	Body weight	Moderate Positive	Limited	Unclear	1
Basal insulin	Body weight	Moderate Negative	Weak	Unclear	1
Behavioral counseling	Body weight	Moderate Positive	Weak	Unclear	1
Boscisucrophage	Body weight	Moderate Positive	Limited	Unclear	1
Calorie restriction	Body weight	Moderate Positive	Limited	Unclear	1
Curcumin plus piperine	BMI	Moderate Positive	Limited	Unclear	1
Curcumin plus piperine	Waist circumference	Moderate Positive	Limited	Unclear	1
Dapagliflozin	Body weight	Moderate Positive	Limited	Unclear	1
Del Immune V Extra bacterial lysate	BMI	Neutral	Weak	Unclear	1
Del Immune V Extra bacterial lysate	Body weight	Neutral	Weak	Unclear	1
Del Immune V Extra bacterial lysate	Waist circumference	Moderate Positive	Limited	Unclear	1
Digital physician Pharmacist collaborative care	Waist circumference	Moderate Positive	Limited	Unclear	1
Digital physician Pharmacist collaborative care	Waist To Hip ratio	Moderate Positive	Limited	Unclear	1
Dulaglutide dose escalation	Body weight	Moderate Positive	Limited	Unclear	1
Exercise therapy	Pregnancy weight gain	Neutral	Weak	Unclear	1
GLP 1 receptor agonists	Body weight	Moderate Positive	Limited	Unclear	1
Insulin Glargine Lixisenatide dosis	BMI	Moderate Positive	Limited	Unclear	1
Insulin Glargine Lixisenatide dosis	Body weight	Moderate Positive	Limited	Unclear	1
Liraglutide	Body weight	Moderate Positive	Limited	Unclear	1
Low Carbohydrate diet	BMI	Moderate Positive	Limited	Unclear	1
Low Carbohydrate diet	Body fat mass	Moderate Positive	Limited	Unclear	1
Low Carbohydrate diet	Body weight	Moderate Positive	Limited	Consistent	2
Mediterranean ketogenic diet	BMI	Moderate Positive	Limited	Unclear	1
Mediterranean ketogenic diet	Body weight	Moderate Positive	Limited	Unclear	1
Mediterranean ketogenic diet	Waist circumference	Moderate Positive	Limited	Unclear	1
Metformin	Body weight	Moderate Positive	Limited	Unclear	1
Multidisciplinary lifestyle intervention for type 2 diabetes remission	BMI	Moderate Positive	Limited	Consistent	2
Multidisciplinary lifestyle intervention for type 2 diabetes remission	Body weight	Moderate Positive	Limited	Consistent	2
Pioglitazone	Body weight	Moderate Negative	Weak	Unclear	1
Probiotics	Body fat mass	Moderate Positive	Weak	Unclear	1
Probiotics	Body weight	Moderate Positive	Weak	Unclear	1
Remote nutrition education on low Carbohydrate diet	BMI	Moderate Positive	Limited	Unclear	1
Remote nutrition education on low Carbohydrate diet	Body weight	Moderate Positive	Limited	Unclear	1
Semaglutide	BMI	Moderate Positive	Limited	Unclear	1
Semaglutide	Body weight	Moderate Positive	Limited	Consistent	2
Telemonitoring	Body weight	Neutral	Weak	Unclear	1
Telephone counseling	BMI	Moderate Positive	Limited	Unclear	1
Tirzepatide	BMI	Moderate Positive	Limited	Unclear	1
Tirzepatide	Body weight	Moderate Positive	Limited	Unclear	1
Very Low Calorie ketogenic diet	BMI	Moderate Positive	Limited	Unclear	1
Very Low Calorie ketogenic diet	Body weight	Moderate Positive	Limited	Unclear	1
Very Low Calorie ketogenic diet	Waist circumference	Moderate Positive	Limited	Unclear	1

Intervention → Outcome

Behavioral lifestyle interventions → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Behavioral lifestyle interventions → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Basal insulin → Body weight

Effectiveness

Moderate Negative

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Behavioral counseling → Body weight

Effectiveness

Moderate Positive

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Boscisucrophage → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Calorie restriction → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Curcumin plus piperine → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Curcumin plus piperine → Waist circumference

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Dapagliflozin → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Del Immune V Extra bacterial lysate → BMI

Effectiveness

Neutral

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Del Immune V Extra bacterial lysate → Body weight

Effectiveness

Neutral

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Del Immune V Extra bacterial lysate → Waist circumference

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Digital physician Pharmacist collaborative care → Waist circumference

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Digital physician Pharmacist collaborative care → Waist To Hip ratio

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Dulaglutide dose escalation → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Exercise therapy → Pregnancy weight gain

Effectiveness

Neutral

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

GLP 1 receptor agonists → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Insulin Glargine Lixisenatide dosis → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Insulin Glargine Lixisenatide dosis → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Liraglutide → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Low Carbohydrate diet → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Low Carbohydrate diet → Body fat mass

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Low Carbohydrate diet → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Consistent

Studies

Intervention → Outcome

Mediterranean ketogenic diet → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Mediterranean ketogenic diet → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Mediterranean ketogenic diet → Waist circumference

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Metformin → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Multidisciplinary lifestyle intervention for type 2 diabetes remission → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Consistent

Studies

Intervention → Outcome

Multidisciplinary lifestyle intervention for type 2 diabetes remission → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Consistent

Studies

Intervention → Outcome

Pioglitazone → Body weight

Effectiveness

Moderate Negative

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Probiotics → Body fat mass

Effectiveness

Moderate Positive

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Probiotics → Body weight

Effectiveness

Moderate Positive

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Remote nutrition education on low Carbohydrate diet → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Remote nutrition education on low Carbohydrate diet → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Semaglutide → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Semaglutide → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Consistent

Studies

Intervention → Outcome

Telemonitoring → Body weight

Effectiveness

Neutral

Strength

Weak

Consistency

Unclear

Studies

Intervention → Outcome

Telephone counseling → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Tirzepatide → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Tirzepatide → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Very Low Calorie ketogenic diet → BMI

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Very Low Calorie ketogenic diet → Body weight

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies

Intervention → Outcome

Very Low Calorie ketogenic diet → Waist circumference

Effectiveness

Moderate Positive

Strength

Limited

Consistency

Unclear

Studies