Research Summary
Analyzed using Evidence Intelligence™

Exercise and Broccoli Supplementation Improve Apolipoprotein Levels in Type 2 Diabetes

Last updated September 11, 2026

Key finding

Apolipoprotein A-I increased by +44.92 ± 6.05 mg/dL.

Exercise training and broccoli sprout supplementation in men with type 2 diabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

Exercise training and broccoli sprout supplementation in men with type 2 diabetes.

Clinical relevance

This study evaluated Exercise training and broccoli sprout supplementation in men with type 2 diabetes.

Keep in mind

Limitations were not clearly described in the extracted text.

Published in

Journal Reference

Publication details and source links for this paper.

Maryam D, Masoumeh G, Farzaneh Z, et al. The Effects of Combined Exercise Training and Broccoli Sprout Supplementation on Apolipoprotein Levels in Men with Type 2 Diabetes. Nutrients. 2025;17(17):2735. doi:10.3390/nu17172735

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Exercise therapy, Sumac supplement, Training + Supplement and Glucose, HDL cholesterol, Insulin, and 5 more.

Primary intervention

Exercise therapy

Primary outcomes

  • Glucose
  • HDL cholesterol
  • Insulin

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

10
Evidence pairs
10
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

3

Related topics

10

Evidence pairs

1168

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 10 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

Cardiometabolic Risk

matched_intervention_and_outcome

Related evidence

Evidence topic

Insulin Resistance

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Glucose

Exercise therapy → Glucose

Exercise therapy → Glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HDL cholesterol

Exercise therapy → HDL cholesterol

Exercise therapy → HDL cholesterol

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Insulin

Exercise therapy → Insulin

Exercise therapy → Insulin

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Insulin resistance

Exercise therapy → Insulin resistance

Exercise therapy → Insulin resistance

Evidence Intelligence™
EvidenceScore™
79
Strong
ImpactScore™
83
Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 3 studies
Add to Evidence Tracker

Apolipoprotein A-I

Sumac supplement → Apolipoprotein A-I

Sumac supplement → Apolipoprotein A-I

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
85
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Apolipoprotein B100

Sumac supplement → Apolipoprotein B100

Sumac supplement → Apolipoprotein B100

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
85
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HOMA-IR (Supplement)

Sumac supplement → HOMA-IR (Supplement)

Sumac supplement → HOMA-IR (Supplement)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
85
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Apolipoprotein A-I

Training + Supplement → Apolipoprotein A-I

Training + Supplement → Apolipoprotein A-I

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Apolipoprotein B100

Training + Supplement → Apolipoprotein B100

Training + Supplement → Apolipoprotein B100

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Apolipoprotein J

Training + Supplement → Apolipoprotein J

Training + Supplement → Apolipoprotein J

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Exercise therapy and Insulin Resistance, Exercise therapy and Adipokine and Angiogenic Markers.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Exercise therapy improve insulin resistance?

Strong Evidence

Exercise therapy may improve insulin resistance.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Insulin resistance

    EvidenceScore™ Strong | EvidenceScore™ 78.6 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Exercise therapy improve hdl cholesterol?

Moderate Evidence

Exercise therapy may improve hdl cholesterol.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    HDL cholesterol

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Exercise therapy improve insulin?

Emerging Evidence

Exercise therapy appears to improve insulin.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Insulin

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Sumac supplement improve apolipoprotein a-i?

Emerging Evidence

Sumac supplement appears to improve apolipoprotein a-i.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Apolipoprotein A-I

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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