Last updated August 24, 2026
Key finding
Increases in 0 V pattern (COMB, 67.0±7.1 vs. 76.0±6.3, P = 0.003)
This study investigated the effects of aerobic and combined exercise on glucose levels in patients with type 2 diabetes, finding significant reductions in glucose levels after exercise sessions.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
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Study focus
This study investigated the effects of aerobic and combined exercise on glucose levels in patients with type 2 diabetes, finding significant reductions in glucose levels after exercise sessions.
These findings highlight the importance of exercise as a non-pharmacological intervention for managing glucose levels in individuals with type 2 diabetes. By incorporating aerobic and resistance exercises into their routines, patients may achieve better glycemic control, potentially reducing the risk of diabetes-related complications.
Effectiveness of interventions remains unclear due to lack of detailed evidence. Study may have limited generalizability to broader populations. Sample size and demographic details were not specified.
Published in
Publication details and source links for this paper.
Franciele RF, Daniel U, Karina RC, et al. Effects of Aerobic and Combined Exercise on Glucose Levels in Patients with Type 2 Diabetes. PLoS ONE. 2013;8(3):e57733. doi:10.1371/journal.pone.0057733
Glucose levels decreased by approximately 16% after both aerobic and combined exercise sessions.
The combined exercise group showed a significant increase in the 0 V pattern (P = 0.003).
The combined exercise group exhibited a significant decrease in the 1 V pattern (P = 0.004).
Evidence network
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This study contributes evidence to Aerobic exercise and 0V glucose symbolic pattern, 1V glucose symbolic pattern, Blood glucose, and 2 more.
This study contributes evidence to
Primary intervention
Aerobic exercise
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
5
Evidence pairs
371
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Contributes evidence
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Contributes evidence
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Primary evidence
Evidence relationship
Related evidence
Evidence relationship
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Core evidence
The primary outcomes reported in this study.
Aerobic exercise → 0V glucose symbolic pattern
Aerobic exercise → 0V glucose symbolic pattern
Aerobic exercise → 1V glucose symbolic pattern
Aerobic exercise → 1V glucose symbolic pattern
Aerobic exercise → Coefficient of variation
Aerobic exercise → Coefficient of variation
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Aerobic Exercise and Fasting Glucose, Aerobic Exercise and 0V glucose symbolic pattern.
This study contributes to the evidence on the following intervention-outcome relationships.
Physical Activity
Physical Activity
Curated evidence collections and hubs this study is part of.
All studies on Aerobic Exercise
Contributes to Aerobic Exercise evidence base.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies measuring 0V glucose symbolic pattern
Measures 0V glucose symbolic pattern as a key outcome.
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3 results
1 results
3 results
3 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Aerobic Exercise appears to improve Fasting Glucose.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Blood glucose
EvidenceScore™ Strong | EvidenceScore™ 77.4 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 7 supporting studies with consistent results and a positive effect signal.
Limitations
Aerobic Exercise appears to improve Glucose Variability.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Coefficient of variation
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Glucose variability
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Aerobic exercise appears to improve 0V glucose symbolic pattern.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
0V glucose symbolic pattern
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Aerobic exercise for 1V glucose symbolic pattern.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
1V glucose symbolic pattern
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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