StrongDecrease
Fasting blood sugar (FBS)
F-Biotic Arishina → Fasting blood sugar (FBS)
F-Biotic Arishina → Fasting blood sugar (FBS)
Evidence profile
StrongDecreaseGlycemic Control
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Research Summary
Analyzed using Evidence Intelligence™
F-Biotic™ improves glycemic control in adults with type 2 diabetes
Key finding
FBS decreased from 150.18 ± 34.78 mg/dL at baseline to 134.24 ± 39.91 mg/dL by the end of the study.
This study evaluated the effectiveness, safety, and tolerability of F-Biotic™ in patients with Type 2 Diabetes Mellitus, finding significant improvements in fasting and postprandial blood sugar levels.
Evidence strength
Moderate confidence
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Some Concerns bias
Last updated July 4, 2026Quick read
Study at a glance
The essential study design details in one scan.
Population
Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes
Intervention
F-Biotic
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Primary outcome
Fasting Blood Sugar (FBS)
Comparator
Placebo Group
Plain-language summary
What this paper says
A plain-language read of the study's main message and where it applies.
Study focus
This study evaluated the effectiveness, safety, and tolerability of F-Biotic™ in patients with Type 2 Diabetes Mellitus, finding significant improvements in fasting and postprandial blood sugar levels.
Clinical relevance
These findings suggest that F-Biotic™ could be a beneficial addition to the management of Type 2 Diabetes Mellitus, particularly in controlling blood sugar levels and enhancing patients' quality of life. Such improvements could lead to better overall diabetes management and potentially reduce the risk of diabetes-related complications.
Keep in mind
No significant changes in HbA1c, fasting insulin, or insulin resistance were observed. The study may have limited generalizability due to specific population characteristics. Effectiveness of F-Biotic™ remains unclear for some outcomes.
Published in
Journal Reference
Publication details and source links for this paper.
Alexander M, John RA, Smiju D, Sheejamol S, Santhosh KAK, Balprakash N. Effectiveness, Safety, and Tolerability of F-Biotic™ in Patients with Type 2 Diabetes Mellitus. Cureus. 2024;16(12):e76053. doi:10.7759/cureus.76053
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Main Effects
Fasting Blood Sugar decreased by 15.94 mg/dL (p=0.037).
Postprandial Blood Sugar decreased by 32.97 mg/dL (p=0).
Quality of Life improved significantly in the F-Biotic group.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to F-Biotic Arishina and Fasting blood sugar (FBS), Fasting insulin levels, GLP-1, and 5 more.
This study contributes evidence to
Primary intervention
F-Biotic Arishina
Primary outcomes
- Fasting blood sugar (FBS)
- Fasting insulin levels
- GLP-1
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
8
Evidence pairs
8
Relationships
2
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 64
2
Related topics
8
Evidence pairs
270
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 8 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Core evidence
Study findings
The primary outcomes reported in this study.
NoneNo Change
Fasting insulin levels
F-Biotic Arishina → Fasting insulin levels
F-Biotic Arishina → Fasting insulin levels
Evidence profile
NoneNo ChangeMetabolic Health
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StrongIncrease
GLP-1
F-Biotic Arishina → GLP-1
F-Biotic Arishina → GLP-1
Evidence profile
StrongIncreaseMetabolic Health
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StrongDecrease
Glucose iAUC (OGTT)
F-Biotic Arishina → Glucose iAUC (OGTT)
F-Biotic Arishina → Glucose iAUC (OGTT)
Evidence profile
StrongDecreaseGlycemic Control
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NoneNo Change
HbA1c
F-Biotic Arishina → HbA1c
F-Biotic Arishina → HbA1c
Evidence profile
NoneNo ChangeGlycemic Control
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NoneNo Change
Insulin resistance
F-Biotic Arishina → Insulin resistance
F-Biotic Arishina → Insulin resistance
Evidence profile
NoneNo ChangeMetabolic Health
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NoneNo Change
lipid profiles
F-Biotic Arishina → lipid profiles
F-Biotic Arishina → lipid profiles
Evidence profile
NoneNo ChangeMetabolic Health
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StrongIncrease
Quality of life
F-Biotic Arishina → Quality of life
F-Biotic Arishina → Quality of life
Evidence profile
StrongIncreasePatient-Reported
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Evidence Suggest
- Fasting Blood Sugar decreased significantly by 15.94 mg/dL.
- Postprandial Blood Sugar decreased significantly by 32.97 mg/dL.
- Quality of Life showed significant improvement in the F-Biotic group.
Who this applies to
- Adults diagnosed with Type 2 Diabetes Mellitus.
- Patients seeking additional management options for blood sugar control.
Keep in Mind
- The study did not assess long-term effects of F-Biotic™.
- Results may not apply to all demographics of diabetes patients.
- Further research is needed to confirm findings across diverse populations.
Between the Lines
- No significant changes in HbA1c, fasting insulin, or insulin resistance were observed.
- The study may have limited generalizability due to specific population characteristics.
- Effectiveness of F-Biotic™ remains unclear for some outcomes.
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on F-Biotic Arishina and Fasting Glucose, F-Biotic Arishina and GLP-1.
Related evidence relationships
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention-outcome relationships.
Included in these evidence collections
Curated evidence collections and hubs this study is part of.
F-Biotic Arishina Evidence Hub
All studies on F-Biotic Arishina
1 studies
intervention_hubContributes to F-Biotic Arishina evidence base.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
1 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
GLP-1 Evidence Hub
All studies measuring GLP-1
1 studies
outcome_hubMeasures GLP-1 as a key outcome.
Quality of Life Outcomes Evidence Hub
All studies measuring Quality of Life Outcomes
1 studies
outcome_hubMeasures Quality of Life Outcomes as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in the evidence archive
Jump to pre-filtered views in the evidence archive.
All studies on F-Biotic Arishina and Fasting blood sugar (FBS)
Intervention: F-Biotic ArishinaOutcome: Fasting blood sugar (FBS)
1 results
All studies on F-Biotic Arishina and GLP-1
Intervention: F-Biotic ArishinaOutcome: GLP-1
1 results
All studies on F-Biotic Arishina
Intervention: F-Biotic Arishina
1 results
All studies measuring Fasting blood sugar (FBS)
Outcome: Fasting blood sugar (FBS)
1 results
All studies measuring GLP-1
Outcome: GLP-1
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does F-Biotic Arishina improve fasting blood sugar (fbs)?
Emerging Evidence
F-Biotic Arishina appears to improve Fasting blood sugar (FBS).
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Fasting blood sugar (FBS)
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does F-Biotic Arishina improve glp-1?
Emerging Evidence
F-Biotic Arishina appears to improve GLP-1.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
GLP-1
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does F-Biotic Arishina improve glucose iauc (ogtt)?
Emerging Evidence
F-Biotic Arishina appears to improve Glucose iAUC (OGTT).
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does F-Biotic Arishina improve quality of life?
Emerging Evidence
F-Biotic Arishina appears to improve Quality of life.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Quality of life
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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