Research Summary
Analyzed using Evidence Intelligence™

Higher BMI and shorter DM duration linked to diabetes remission after surgery

Last updated August 22, 2026

Key finding

HbA1c decreased from 7.90% to 6.66% after 3 months.

This study evaluated the DiaRem scoring system's sensitivity in predicting diabetes resolution post-bariatric surgery in morbidly obese patients.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

Non-randomized CT

Follow-up

Short-Term (≤3 mo)

Risk of bias

High Risk

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the DiaRem scoring system's sensitivity in predicting diabetes resolution post-bariatric surgery in morbidly obese patients.

Clinical relevance

The findings highlight the potential of bariatric surgery as an effective treatment for Type 2 diabetes in morbidly obese patients. Understanding the predictive value of the DiaRem score can help clinicians tailor interventions and improve patient outcomes, ultimately addressing the growing obesity and diabetes epidemic.

Keep in mind

Non-randomized study design may introduce bias. Sample size and demographic details were not specified. Unclear generalizability to non-morbidly obese populations.

Published in

Journal Reference

Publication details and source links for this paper.

Alexander M, John RA, Bandar SA, et al. Sensitivity of the DiaRem Scoring System for Predicting Resolution of Type 2 Diabetes in Morbidly Obese Patients Undergoing Bariatric Surgery. Cureus. 2021;13(11):e20064. doi:10.7759/cureus.20064

Main Effects

HbA1c decreased from 7.90% to 6.66% after 3 months.

HbA1c decreased from 7.90% to 6.21% after 6 months.

HbA1c decreased from 7.90% to 6.12% after 12 months.

Fasting blood glucose decreased from 11.4 mmol/L before surgery to 6.34 mmol/L after surgery.

Evidence network

How this study fits

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Evidence Context

This study contributes evidence to Bariatric surgery and Distribution of DiaRem scores among patients, Fasting blood sugar (FBS), HbA1c.

Primary intervention

Bariatric surgery

Primary outcomes

  • Distribution of DiaRem scores among patients
  • Fasting blood sugar (FBS)
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

3
Evidence pairs
3
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

3

Related topics

3

Evidence pairs

719

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 3 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence relationship

Bariatric Procedures and Fasting Glucose

Related evidence

Evidence relationship

Bariatric Procedures and HbA1c

Save evidence

Evidence topic

Glycemic Control

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Core evidence

Study findings

The primary outcomes reported in this study.

Distribution of DiaRem scores among patients

Bariatric surgery → Distribution of DiaRem scores among patients

Bariatric surgery → Distribution of DiaRem scores among patients

Evidence Intelligence™
EvidenceScore™
51
Emerging
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting blood sugar (FBS)

Bariatric surgery → Fasting blood sugar (FBS)

Bariatric surgery → Fasting blood sugar (FBS)

Evidence Intelligence™
EvidenceScore™
51
Emerging
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Bariatric surgery → HbA1c

Bariatric surgery → HbA1c

Evidence Intelligence™
EvidenceScore™
65
Moderate
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • HbA1c levels significantly decreased by 1.78% after 12 months.
  • Fasting blood glucose reduced by 5.06 mmol/L post-surgery.
  • DiaRem scores indicated varying likelihoods of diabetes resolution among patients.
who this applies

Who this applies to

  • Morbidly obese patients considering bariatric surgery.
  • Individuals with Type 2 diabetes seeking surgical intervention.
keep in mind

Keep in Mind

  • Results may not apply to patients with mild obesity.
  • Long-term effects beyond 12 months were not assessed.
  • The study lacked a control group for comparison.
between the lines

Between the Lines

  • Non-randomized study design may introduce bias.
  • Sample size and demographic details were not specified.
  • Unclear generalizability to non-morbidly obese populations.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Bariatric Procedures and HbA1c, Bariatric Procedures and Distribution of DiaRem scores among patients.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Bariatric Procedures improve fasting glucose?

Strong Evidence

Bariatric Procedures may improve Fasting Glucose.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Fasting blood sugar (FBS)

    EvidenceScore™ Emerging | EvidenceScore™ 50.7 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 5 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
5 supporting studiesUpdated: Aug 2026

Does Bariatric Procedures improve HbA1c?

Moderate Evidence

Bariatric Procedures appears to improve HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Moderate | EvidenceScore™ 65.3 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
4 supporting studiesUpdated: Aug 2026

Does Bariatric surgery improve distribution of diarem scores among patients?

Emerging Evidence

Current evidence does not show a clear benefit of Bariatric surgery for Distribution of DiaRem scores among patients.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Distribution of DiaRem scores among patients

    EvidenceScore™ Emerging | EvidenceScore™ 50.7 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026
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