Last updated June 15, 2026
Key finding
Weight decreased by 12.9 kg in the OGTT-cleared group.
This study evaluated the effects of a one-year lifestyle intervention on type 2 diabetes patients who achieved remission, finding significant improvements in various metabolic parameters.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the effects of a one-year lifestyle intervention on type 2 diabetes patients who achieved remission, finding significant improvements in various metabolic parameters.
These findings highlight the potential of lifestyle modifications as a powerful strategy for managing type 2 diabetes. By demonstrating significant improvements in metabolic health, this study underscores the importance of behavioral interventions in achieving remission and reducing the risk of diabetes-related complications.
Single-arm study design limits comparison to control groups. Results may not be generalizable to all type 2 diabetes patients. Potential for unmeasured confounders affecting outcomes.
Published in
Publication details and source links for this paper.
Pramod T, Nidhi K, Diptika T, et al. Achieving diabetes remission through a structured lifestyle modification program: A quasi-experimental study. PLOS ONE. 2024. doi:10.1371/journal.pone.0302777
52% of participants cleared the OGTT.
Weight decreased by an average of 12.9 kg.
HbA1c levels decreased by 17.1 mmol/mol.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Complex lifestyle intervention and Body Mass Index (BMI) change, Diabetic ketoacidosis, Diabetic microvascular complication multimorbidity, and 12 more.
This study contributes evidence to
Primary intervention
Complex lifestyle intervention
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
6
Related topics
15
Evidence pairs
1153
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Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence relationship
Related evidence
Evidence relationship
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Core evidence
The primary outcomes reported in this study.
Complex lifestyle intervention → Body Mass Index (BMI) change
Complex lifestyle intervention → Body Mass Index (BMI) change
Complex lifestyle intervention → Diabetic ketoacidosis
Complex lifestyle intervention → Diabetic ketoacidosis
Complex lifestyle intervention → Diabetic microvascular complication multimorbidity
Complex lifestyle intervention → Diabetic microvascular complication multimorbidity
Complex lifestyle intervention → Diabetic nephropathy incidence
Complex lifestyle intervention → Diabetic nephropathy incidence
Complex lifestyle intervention → Diabetic neuropathy incidence
Complex lifestyle intervention → Diabetic neuropathy incidence
Complex lifestyle intervention → Diabetic retinopathy incidence
Complex lifestyle intervention → Diabetic retinopathy incidence
Complex lifestyle intervention → Fasting blood sugar (FBS)
Complex lifestyle intervention → Fasting blood sugar (FBS)
Complex lifestyle intervention → Fasting insulin levels
Complex lifestyle intervention → Fasting insulin levels
Complex lifestyle intervention → Glucose iAUC (OGTT)
Complex lifestyle intervention → Glucose iAUC (OGTT)
Complex lifestyle intervention → Homeostatic model assessment for insulin resistance (HOMA-IR) change
Complex lifestyle intervention → Homeostatic model assessment for insulin resistance (HOMA-IR) change
Complex lifestyle intervention → Postprandial blood glucose
Complex lifestyle intervention → Postprandial blood glucose
Complex lifestyle intervention → Urinary albumin-to-creatinine ratio
Complex lifestyle intervention → Urinary albumin-to-creatinine ratio
Complex lifestyle intervention → Waist-to-hip ratio
Complex lifestyle intervention → Waist-to-hip ratio
Complex lifestyle intervention → Weight change
Complex lifestyle intervention → Weight change
Evidence Library
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Diabetes Self-Management Education and Support (DSMES) Programs and HbA1c, Diabetes Self-Management Education and Support (DSMES) Programs and Body Mass Index.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies on Diabetes Self-Management Education and Support (DSMES) Programs
Contributes to Diabetes Self-Management Education and Support (DSMES) Programs evidence base.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies measuring Body Mass Index
Measures Body Mass Index as a key outcome.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
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Published within the last 2 years.
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2 results
1 results
2 results
2 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Diabetes Self-Management Education and Support (DSMES) Programs may improve Fasting Glucose.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Fasting blood sugar (FBS)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 11 supporting studies with generally consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs may improve Body Mass Index.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Body Mass Index (BMI) change
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 15 supporting studies with generally consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs may improve HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 32 supporting studies with generally consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Postprandial and OGTT Glucose.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Postprandial blood glucose
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 5 supporting studies with consistent results and a positive effect signal.
Limitations
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