Research Summary
Analyzed using Evidence Intelligence™

Non-surgical periodontal treatment improves clinical indices in diabetic patients

Last updated July 22, 2026

Key finding

GI dropped from 1.92 ± 0.27 to 0.71 ± 0.14 after the intervention (P<0.001).

This study investigated the impact of non-surgical periodontal treatment on clinical indices and salivary adipokines in diabetic patients with periodontitis, finding significant improvements in several clinical measures.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study investigated the impact of non-surgical periodontal treatment on clinical indices and salivary adipokines in diabetic patients with periodontitis, finding significant improvements in several clinical measures.

Clinical relevance

Improving periodontal health in diabetic patients is crucial as it can potentially reduce complications associated with both diabetes and periodontal disease. This study highlights the effectiveness of non-surgical treatments in managing periodontal conditions, which may enhance overall health outcomes for this vulnerable population.

Keep in mind

Study design limited to a single-arm without a control group Sample size not specified, affecting generalizability No long-term follow-up to assess sustained effects

Published in

Journal Reference

Publication details and source links for this paper.

Narges Z, Shima G, Mari A, Farnoosh A, Mehran MA. The Effect of Non-Surgical Periodontal Treatment on Clinical Indices and Salivary Adipokines in Diabetic Patients with Periodontitis. Journal of Dental Research, Dental Clinics, Dental Prospects. 2020;14(3):199-205. doi:10.34172/joddd.2020.029

Main Effects

Gingival index decreased from 1.92 to 0.71 (P<0.001)

Periodontal probing depth decreased from 4.53 mm to 2.18 mm (P<0.001)

Plaque index decreased from 72.6% to 25.3% (P<0.001)

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Non-surgical periodontal treatment and Clinical attachment level, Decrease in salivary progranulin levels, Gingival Index (GI), and 4 more.

Primary intervention

Non-surgical periodontal treatment

Primary outcomes

  • Clinical attachment level
  • Decrease in salivary progranulin levels
  • Gingival Index (GI)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
0
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 50

0

Related topics

7

Evidence pairs

0

Related studies

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 0 direct semantic evidence topics

Core evidence

Study findings

The primary outcomes reported in this study.

Clinical attachment level

Non-surgical periodontal treatment → Clinical attachment level

Non-surgical periodontal treatment → Clinical attachment level

Evidence Intelligence™
EvidenceScore™
84
Strong
ImpactScore™
76
Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 10 studies
Add to Evidence Tracker

Decrease in salivary progranulin levels

Non-surgical periodontal treatment → Decrease in salivary progranulin levels

Non-surgical periodontal treatment → Decrease in salivary progranulin levels

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Gingival Index (GI)

Non-surgical periodontal treatment → Gingival Index (GI)

Non-surgical periodontal treatment → Gingival Index (GI)

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

Periodontal probing depth

Non-surgical periodontal treatment → Periodontal probing depth

Non-surgical periodontal treatment → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
85
Positive
ConsistencyScore™
90
consistent
Supporting studies: Based on 11 studies
Add to Evidence Tracker

Plaque Index (PI)

Non-surgical periodontal treatment → Plaque Index (PI)

Non-surgical periodontal treatment → Plaque Index (PI)

Evidence Intelligence™
EvidenceScore™
82
Strong
ImpactScore™
93
Very Positive
ConsistencyScore™
86
consistent
Supporting studies: Based on 7 studies
Add to Evidence Tracker

Salivary chemerin

Non-surgical periodontal treatment → Salivary chemerin

Non-surgical periodontal treatment → Salivary chemerin

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Salivary visfatin levels

Non-surgical periodontal treatment → Salivary visfatin levels

Non-surgical periodontal treatment → Salivary visfatin levels

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Gingival index showed a significant decrease of 1.21 units (P<0.001)
  • Periodontal probing depth reduced by 2.35 mm (P<0.001)
  • Plaque index decreased by 47.3% (P<0.001)
who this applies

Who this applies to

  • Diabetic patients aged 30-70 with periodontitis
  • Individuals seeking non-surgical periodontal treatment
keep in mind

Keep in Mind

  • Results may not be generalizable due to the non-randomized design
  • Short-term outcomes assessed; long-term effects remain unknown
  • Salivary adipokine levels did not show significant changes
between the lines

Between the Lines

  • Study design limited to a single-arm without a control group
  • Sample size not specified, affecting generalizability
  • No long-term follow-up to assess sustained effects

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Non-surgical periodontal treatment and Clinical attachment level, Non-surgical periodontal treatment and Periodontal probing depth.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Non-surgical periodontal treatment improve clinical attachment level?

Strong Evidence

Non-surgical periodontal treatment may improve Clinical attachment level.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Clinical attachment level

    EvidenceScore™ Strong | EvidenceScore™ 84.4 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Non-surgical periodontal treatment improve periodontal probing depth?

Strong Evidence

Non-surgical periodontal treatment may improve Periodontal probing depth.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Periodontal probing depth

    EvidenceScore™ Strong | EvidenceScore™ 83.4 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Non-surgical periodontal treatment improve plaque index (pi)?

Strong Evidence

Non-surgical periodontal treatment appears to improve Plaque Index (PI).

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Plaque Index (PI)

    EvidenceScore™ Strong | EvidenceScore™ 81.9 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Non-surgical periodontal treatment improve gingival index (gi)?

Strong Evidence

Non-surgical periodontal treatment appears to improve Gingival Index (GI).

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Gingival Index (GI)

    EvidenceScore™ Strong | EvidenceScore™ 79.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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