Research Summary
Analyzed using Evidence Intelligence™

Periodontal Therapy May Improve Glycemic Control in Diabetes

Last updated July 18, 2026

Key finding

PI decreased by 0.45 (from 1.60 to 1.15) in the test group.

This study evaluated the impact of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes, finding significant improvements in periodontal health but no significant change in HbA1c levels.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the impact of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes, finding significant improvements in periodontal health but no significant change in HbA1c levels.

Clinical relevance

Improving periodontal health is crucial for patients with diabetes, as oral health can influence overall health outcomes. While this study showed that non-surgical periodontal therapy can enhance gum health, the lack of impact on glycemic control suggests that additional strategies may be necessary to manage diabetes effectively.

Keep in mind

The study did not find significant changes in HbA1c levels. Effectiveness of the intervention on glycemic control remains unclear. The study's sample size and demographic characteristics may limit generalizability.

Published in

Journal Reference

Publication details and source links for this paper.

Ruchi R, Mahalinga B, Subraya BG, Kumari U, Vishal S, Ayon G. Effect of Non-Surgical Periodontal Therapy on Glycemic Control in Patients with Type 2 Diabetes. Journal of Pharmacy & Bioallied Sciences. 2026;18(Suppl 1):S215-S217. doi:10.4103/jpbs.jpbs_1318_25

Main Effects

Plaque Index decreased by 0.45 (p=0.001) in the treatment group.

Gingival Index decreased by 0.46 (p=0.001) in the treatment group.

Modified Sulcus Bleeding Index decreased by 0.55 (p=0.001) in the treatment group.

Clinical Attachment Loss decreased by 0.37 (p=0.001) in the treatment group.

Evidence network

How this study fits

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Evidence Context

This study contributes evidence to Non-surgical periodontal treatment and Clinical attachment level, Gingival Index (GI), HbA1c, and 3 more.

Primary intervention

Non-surgical periodontal treatment

Primary outcomes

  • Clinical attachment level
  • Gingival Index (GI)
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

6
Evidence pairs
6
Relationships
1
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 63

1

Related topics

6

Evidence pairs

310

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 6 evidence relationships
  • Includes primary outcome data
  • Linked to 1 direct semantic evidence topic

Topic contributions

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

HbA1c Reduction

matched_outcome

Core evidence

Study findings

The primary outcomes reported in this study.

Clinical attachment level

Non-surgical periodontal treatment → Clinical attachment level

Non-surgical periodontal treatment → Clinical attachment level

Evidence Intelligence™
EvidenceScore™
84
Strong
ImpactScore™
76
Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 10 studies
Add to Evidence Tracker

Gingival Index (GI)

Non-surgical periodontal treatment → Gingival Index (GI)

Non-surgical periodontal treatment → Gingival Index (GI)

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 4 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
75
consistent
Supporting studies: Based on 4 studies
Add to Evidence Tracker

HbA1c

Non-surgical periodontal treatment → HbA1c

Non-surgical periodontal treatment → HbA1c

Evidence Intelligence™
EvidenceScore™
84
Strong
ImpactScore™
70
Positive
ConsistencyScore™
56
generally_consistent
Supporting studies: Based on 10 studies
Add to Evidence Tracker

Modified Sulcus Bleeding Index (mSBI)

Non-surgical periodontal treatment → Modified Sulcus Bleeding Index (mSBI)

Non-surgical periodontal treatment → Modified Sulcus Bleeding Index (mSBI)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Periodontal probing depth

Non-surgical periodontal treatment → Periodontal probing depth

Non-surgical periodontal treatment → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
85
Positive
ConsistencyScore™
90
consistent
Supporting studies: Based on 11 studies
Add to Evidence Tracker

Plaque Index (PI)

Non-surgical periodontal treatment → Plaque Index (PI)

Non-surgical periodontal treatment → Plaque Index (PI)

Evidence Intelligence™
EvidenceScore™
82
Strong
ImpactScore™
93
Very Positive
ConsistencyScore™
86
consistent
Supporting studies: Based on 7 studies
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Significant reductions in periodontal indices were observed, indicating improved gum health.
  • HbA1c levels did not differ significantly, suggesting no impact on glycemic control.
  • The study highlights the need for additional strategies to manage diabetes.
who this applies

Who this applies to

  • Adults diagnosed with type 2 diabetes.
  • Patients experiencing periodontal disease.
keep in mind

Keep in Mind

  • The lack of significant change in HbA1c levels suggests limited impact on diabetes management.
  • Results may not be applicable to populations outside the study's demographic.
  • Further research is needed to explore the relationship between periodontal health and glycemic control.
between the lines

Between the Lines

  • The study did not find significant changes in HbA1c levels.
  • Effectiveness of the intervention on glycemic control remains unclear.
  • The study's sample size and demographic characteristics may limit generalizability.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Non-surgical periodontal treatment and Clinical attachment level, Non-surgical periodontal treatment and HbA1c.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Non-surgical periodontal treatment improve clinical attachment level?

Strong Evidence

Non-surgical periodontal treatment may improve Clinical attachment level.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Clinical attachment level

    EvidenceScore™ Strong | EvidenceScore™ 84.4 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Non-surgical periodontal treatment improve HbA1c?

Strong Evidence

Non-surgical periodontal treatment may improve HbA1c.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 83.6 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Non-surgical periodontal treatment improve periodontal probing depth?

Strong Evidence

Non-surgical periodontal treatment may improve Periodontal probing depth.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Periodontal probing depth

    EvidenceScore™ Strong | EvidenceScore™ 83.4 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Non-surgical periodontal treatment improve plaque index (pi)?

Strong Evidence

Non-surgical periodontal treatment appears to improve Plaque Index (PI).

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Plaque Index (PI)

    EvidenceScore™ Strong | EvidenceScore™ 81.9 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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