Research Summary
Analyzed using Evidence Intelligence™

Periodontal treatment improves metabolic control in Type 2 diabetes

Last updated August 16, 2026

Key finding

Gingival index decreased significantly.

This study investigated the impact of non-surgical periodontal treatment on metabolic control in Type 2 diabetes patients with chronic periodontitis, finding significant improvements in several clinical parameters.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study investigated the impact of non-surgical periodontal treatment on metabolic control in Type 2 diabetes patients with chronic periodontitis, finding significant improvements in several clinical parameters.

Clinical relevance

Improving periodontal health in diabetic patients is crucial as it may lead to better overall metabolic control. This study highlights the importance of integrating dental care into diabetes management, potentially reducing complications associated with both conditions.

Keep in mind

Effectiveness of treatment remains unclear due to study design. Single-arm study limits generalizability of findings. Potential confounding factors were not fully controlled.

Published in

Journal Reference

Publication details and source links for this paper.

Sachin S, Priyanshu RS, Rohit S, Sanjay KS, Anjali S. Effect of periodontal therapy on metabolic control in Type 2 diabetes mellitus patients with chronic periodontitis. Journal of Pharmacy & Bioallied Sciences. 2021;13(Suppl 1):S706-S710. doi:10.4103/jpbs.JPBS_692_20

Main Effects

Gingival index decreased significantly by -0.58 (p=0.001).

Plaque index decreased significantly by -28.4 (p=0.001).

HbA1c decreased significantly, indicating improved metabolic control.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Non-surgical periodontal treatment and Clinical attachment level, Gingival Index (GI), HbA1c, and 3 more.

Primary intervention

Non-surgical periodontal treatment

Primary outcomes

  • Clinical attachment level
  • Gingival Index (GI)
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

6
Evidence pairs
6
Relationships
1
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 59

1

Related topics

6

Evidence pairs

348

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 6 evidence relationships
  • Includes primary outcome data
  • Linked to 1 direct semantic evidence topic

Topic contributions

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

HbA1c Reduction

matched_outcome

Core evidence

Study findings

The primary outcomes reported in this study.

Clinical attachment level

Non-surgical periodontal treatment → Clinical attachment level

Non-surgical periodontal treatment → Clinical attachment level

Evidence Intelligence™
EvidenceScore™
84
Strong
ImpactScore™
76
Positive
ConsistencyScore™
73
generally_consistent
Supporting studies: Based on 13 studies
Add to Evidence Tracker

Gingival Index (GI)

Non-surgical periodontal treatment → Gingival Index (GI)

Non-surgical periodontal treatment → Gingival Index (GI)

Evidence Intelligence™
EvidenceScore™
82
Strong
ImpactScore™
100
Very Positive
ConsistencyScore™
67
generally_consistent
Supporting studies: Based on 6 studies
Add to Evidence Tracker

HbA1c

Non-surgical periodontal treatment → HbA1c

Non-surgical periodontal treatment → HbA1c

Evidence Intelligence™
EvidenceScore™
84
Strong
ImpactScore™
73
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 13 studies
Add to Evidence Tracker

Modified Sulcus Bleeding Index (mSBI)

Non-surgical periodontal treatment → Modified Sulcus Bleeding Index (mSBI)

Non-surgical periodontal treatment → Modified Sulcus Bleeding Index (mSBI)

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Periodontal probing depth

Non-surgical periodontal treatment → Periodontal probing depth

Non-surgical periodontal treatment → Periodontal probing depth

Evidence Intelligence™
EvidenceScore™
83
Strong
ImpactScore™
88
Very Positive
ConsistencyScore™
92
consistent
Supporting studies: Based on 14 studies
Add to Evidence Tracker

Plaque Index (PI)

Non-surgical periodontal treatment → Plaque Index (PI)

Non-surgical periodontal treatment → Plaque Index (PI)

Evidence Intelligence™
EvidenceScore™
84
Strong
ImpactScore™
94
Very Positive
ConsistencyScore™
89
consistent
Supporting studies: Based on 9 studies
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • Gingival index improved significantly with a decrease of -0.58.
  • Plaque index showed a significant reduction of -28.4.
  • HbA1c levels decreased significantly, indicating better blood sugar control.
who this applies

Who this applies to

  • Adults diagnosed with Type 2 diabetes.
  • Patients suffering from chronic periodontitis.
keep in mind

Keep in Mind

  • Results may not apply to all demographics or age groups.
  • Further research is needed to confirm findings across larger populations.
  • Study design limitations may affect the interpretation of effectiveness.
between the lines

Between the Lines

  • Effectiveness of treatment remains unclear due to study design.
  • Single-arm study limits generalizability of findings.
  • Potential confounding factors were not fully controlled.

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Non-surgical periodontal treatment and Clinical attachment level, Non-surgical periodontal treatment and Plaque Index (PI).

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Non-surgical periodontal treatment improve clinical attachment level?

Strong Evidence

Non-surgical periodontal treatment may improve Clinical attachment level.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Clinical attachment level

    EvidenceScore™ Strong | EvidenceScore™ 84.3 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026

Does Non-surgical periodontal treatment improve plaque index (pi)?

Strong Evidence

Non-surgical periodontal treatment appears to improve Plaque Index (PI).

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Plaque Index (PI)

    EvidenceScore™ Strong | EvidenceScore™ 83.9 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026

Does Non-surgical periodontal treatment improve HbA1c?

Strong Evidence

Non-surgical periodontal treatment may improve HbA1c.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 83.8 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026

Does Non-surgical periodontal treatment improve periodontal probing depth?

Strong Evidence

Non-surgical periodontal treatment appears to improve Periodontal probing depth.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Periodontal probing depth

    EvidenceScore™ Strong | EvidenceScore™ 83.5 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026
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