Last updated September 2, 2026
Key finding
PYY increased significantly after control treatment (P = 0.013).
This study investigated the impact of prebiotic fibers on appetite regulation in individuals with type 2 diabetes, revealing no significant differences in appetite-related hormones or ratings between the interventions.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the impact of prebiotic fibers on appetite regulation in individuals with type 2 diabetes, revealing no significant differences in appetite-related hormones or ratings between the interventions.
Understanding appetite regulation is crucial for managing type 2 diabetes, as it can influence dietary choices and weight management. The findings suggest that while prebiotic fibers may not significantly impact appetite hormones or ratings, further research could explore their potential benefits in other areas of diabetes management.
The sample size may limit the generalizability of the findings. The study did not assess long-term effects of prebiotic fibers. Potential confounding factors were not fully controlled.
Published in
Publication details and source links for this paper.
Eline B, Sedegheh G, Kåre IB, Oda KSH, Per MT, Anne-Marie A. The effect of prebiotic fibres on appetite regulation in subjects with type 2 diabetes: a randomized controlled trial. Journal of Nutritional Science. 2021;10:e72. doi:10.1017/jns.2021.70
Ghrelin levels showed no change between treatments (P = 0.71).
Peptide YY levels increased significantly after control treatment (P = 0.013).
Hunger ratings did not differ between treatments (P = 0.366).
Satiety ratings showed no significant difference (P = 0.644).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Inulin-type fructans and Fullness ratings assessed using a visual analogue scale, Ghrelin, Hunger scores, and 3 more.
This study contributes evidence to
Primary intervention
Inulin-type fructans
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
6
Evidence pairs
18
Related studies
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_intervention
Core evidence
The primary outcomes reported in this study.
Inulin-type fructans → Fullness ratings assessed using a visual analogue scale
Inulin-type fructans → Fullness ratings assessed using a visual analogue scale
Inulin-type fructans → Peptide YY (PYY) levels after RYGB
Inulin-type fructans → Peptide YY (PYY) levels after RYGB
Inulin-type fructans → Prospective food consumption ratings
Inulin-type fructans → Prospective food consumption ratings
Evidence Library
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Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Probiotics and Synbiotics and Fullness ratings assessed using a visual analogue scale, Probiotics and Synbiotics and Ghrelin.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Fullness ratings assessed using a visual analogue scale
Measures Fullness ratings assessed using a visual analogue scale as a key outcome.
All studies measuring Ghrelin
Measures Ghrelin as a key outcome.
All studies on Probiotics and Synbiotics
Contributes to Probiotics and Synbiotics evidence base.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Current evidence does not show a clear benefit of Inulin-type fructans for fullness ratings assessed using a visual analogue scale.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fullness ratings assessed using a visual analogue scale
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Inulin-type fructans for ghrelin.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Ghrelin
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Inulin-type fructans for hunger scores.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Hunger scores
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Inulin-type fructans for peptide yy (PYY) levels after rygb.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Peptide YY (PYY) levels after RYGB
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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