StrongDecrease
Fasting blood sugar (FBS)
Sumac supplement → Fasting blood sugar (FBS)
Sumac supplement → Fasting blood sugar (FBS)
Evidence profile
StrongDecreaseGlycemic Control
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Research Summary
Analyzed using Evidence Intelligence™
Sumac improves diabetes control in type 2 diabetes patients
Key finding
FBS decreased significantly from 147 (122, 167) to 100 (92, 121) with p=0.002.
This study investigated the anti-diabetic effects of sumac in patients with type 2 diabetes, finding significant improvements in fasting blood sugar and HbA1C levels.
Evidence strength
Moderate confidence
Study type
RCTs
Follow-up
Extended (5–20+ y)
Some Concerns bias
Last updated July 5, 2026Quick read
Study at a glance
The essential study design details in one scan.
Population
Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes
Intervention
Sumac supplement
Study type
RCTs
Follow-up
Extended (5–20+ y)
Primary outcome
Fasting Blood Sugar (FBS)
Comparator
Calcium dibasic phosphate capsule
Plain-language summary
What this paper says
A plain-language read of the study's main message and where it applies.
Study focus
This study investigated the anti-diabetic effects of sumac in patients with type 2 diabetes, finding significant improvements in fasting blood sugar and HbA1C levels.
Clinical relevance
These findings suggest that sumac could be a beneficial dietary supplement for managing blood sugar levels in type 2 diabetes patients. As diabetes management is crucial for preventing complications, incorporating natural supplements like sumac may enhance treatment strategies.
Keep in mind
The study did not assess long-term effects of sumac supplementation. Sample size and demographic diversity may limit generalizability. No significant changes were observed in total cholesterol, LDL, or triglycerides.
Published in
Journal Reference
Publication details and source links for this paper.
Hossein A, Soleiman M, Mohsen Y, Siamak N, Shervin A, AliSina S. The anti-diabetic effect of sumac in patients with type 2 diabetes: A double-blind randomized controlled trial. Caspian Journal of Internal Medicine. 2025;16(3):417-423. doi:10.22088/cjim.16.3.417
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Main Effects
Fasting Blood Sugar decreased significantly from 147 mg/dL to 100 mg/dL (p=0.002).
HbA1C decreased significantly from 7.74% to 6.47% (p=0.007).
HDL Cholesterol increased significantly from 46 mg/dL to 50 mg/dL (p<0.001).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Sumac supplement and Fasting blood sugar (FBS), HDL cholesterol, HbA1c, and 3 more.
This study contributes evidence to
Primary intervention
Sumac supplement
Primary outcomes
- Fasting blood sugar (FBS)
- HDL cholesterol
- HbA1c
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
6
Evidence pairs
6
Relationships
2
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
2
Related topics
6
Evidence pairs
270
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 6 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Core evidence
Study findings
The primary outcomes reported in this study.
StrongDecrease
HbA1c
Sumac supplement → HbA1c
Sumac supplement → HbA1c
Evidence profile
StrongDecreaseGlycemic Control
Unlock full evidence details
StrongIncrease
HDL cholesterol
Sumac supplement → HDL cholesterol
Sumac supplement → HDL cholesterol
Evidence profile
StrongIncreaseMetabolic Health
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NoneNo Change
LDL cholesterol
Sumac supplement → LDL cholesterol
Sumac supplement → LDL cholesterol
Evidence profile
NoneNo ChangeMetabolic Health
Unlock full evidence details
NoneNo Change
Total cholesterol
Sumac supplement → Total cholesterol
Sumac supplement → Total cholesterol
Evidence profile
NoneNo ChangeMetabolic Health
Unlock full evidence details
NoneNo Change
Triglycerides
Sumac supplement → Triglycerides
Sumac supplement → Triglycerides
Evidence profile
NoneNo ChangeMetabolic Health
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Evidence Suggest
- Fasting Blood Sugar decreased by 47 mg/dL with p=0.002.
- HbA1C reduced by 1.27% with p=0.007.
- HDL Cholesterol increased by 4 mg/dL with p<0.001.
Who this applies to
- Adults diagnosed with type 2 diabetes.
- Individuals seeking dietary supplements for blood sugar management.
Keep in Mind
- Results are based on a specific population and may not apply to all diabetes patients.
- Further research is needed to confirm long-term benefits of sumac.
- The study did not evaluate the impact of lifestyle factors on outcomes.
Between the Lines
- The study did not assess long-term effects of sumac supplementation.
- Sample size and demographic diversity may limit generalizability.
- No significant changes were observed in total cholesterol, LDL, or triglycerides.
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Sumac supplement and Fasting Glucose, Sumac supplement and HbA1c.
Related evidence relationships
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention-outcome relationships.
Included in these evidence collections
Curated evidence collections and hubs this study is part of.
Adipokine and Angiogenic Markers Evidence Hub
All studies measuring Adipokine and Angiogenic Markers
1 studies
outcome_hubMeasures Adipokine and Angiogenic Markers as a key outcome.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
1 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
HbA1c Evidence Hub
All studies measuring HbA1c
1 studies
outcome_hubMeasures HbA1c as a key outcome.
Sumac supplement Evidence Hub
All studies on Sumac supplement
1 studies
intervention_hubContributes to Sumac supplement evidence base.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in the evidence archive
Jump to pre-filtered views in the evidence archive.
All studies on Sumac supplement and Fasting blood sugar (FBS)
Intervention: Sumac supplementOutcome: Fasting blood sugar (FBS)
1 results
All studies on Sumac supplement and HbA1c
Intervention: Sumac supplementOutcome: HbA1c
1 results
All studies on Sumac supplement
Intervention: Sumac supplement
1 results
All studies measuring Fasting blood sugar (FBS)
Outcome: Fasting blood sugar (FBS)
1 results
All studies measuring HbA1c
Outcome: HbA1c
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Sumac supplement improve fasting blood sugar (fbs)?
Emerging Evidence
Sumac supplement appears to improve Fasting blood sugar (FBS).
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Fasting blood sugar (FBS)
EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Sumac supplement improve hdl cholesterol?
Emerging Evidence
Sumac supplement appears to improve HDL cholesterol.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
HDL cholesterol
EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Sumac supplement improve HbA1c?
Emerging Evidence
Sumac supplement appears to improve HbA1c.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Sumac supplement improve ldl cholesterol?
Limited Evidence
Current evidence does not show a clear benefit of Sumac supplement for LDL cholesterol.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
LDL cholesterol
EvidenceScore™ Limited | EvidenceScore™ 35.4 | neutral | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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