Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
Curcumin may improve glucose control in older adults with prediabetes
Last updated September 4, 2026
Key finding
HbA1c levels significantly decreased in the curcumin group.
Curcumin supplementation was studied for its effects on glucose homeostasis in older adults with prediabetes, showing a significant reduction in HbA1c levels.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
Curcumin supplementation was studied for its effects on glucose homeostasis in older adults with prediabetes, showing a significant reduction in HbA1c levels.
Clinical relevance
Managing glucose levels is crucial for preventing diabetes and its complications. The reduction in HbA1c levels among participants taking curcumin suggests that it could be a beneficial supplement for older adults at risk of diabetes, potentially leading to better long-term health outcomes.
Keep in mind
The study did not measure long-term effects beyond the intervention period. Sample size and demographic diversity may limit generalizability. No significant changes were observed in several metabolic parameters.
Published in
Journal Reference
Publication details and source links for this paper.
Gopal L, Tyler JG, Jing L, et al. Curcumin Supplementation Improves Glucose Homeostasis in Older Adults with Prediabetes. Nutrients. 2025;17(13):2164. doi:10.3390/nu17132164
Main Effects
HbA1c levels significantly decreased by 0.25% (p=0.044) in the curcumin group.
Blood glucose levels showed no significant change in both curcumin and placebo groups.
Serum insulin levels remained stable in both groups.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Curcumin supplementation and BMI, Blood glucose, Fasting insulin levels, and 3 more.
This study contributes evidence to
Primary intervention
Curcumin supplementation
Primary outcomes
- BMI
- Blood glucose
- Fasting insulin levels
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
6
Evidence pairs
6
Relationships
5
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 72
5
Related topics
6
Evidence pairs
2128
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 6 evidence relationships
- Includes primary outcome data
- Linked to 5 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence relationship
Curcumin Supplements and HbA1c
Related evidence
Evidence relationship
Curcumin Supplements and Fasting Glucose
Save evidence
Evidence relationship
Curcumin Supplements and Body Mass Index
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerFasting insulin levels
Curcumin supplementation → Fasting insulin levels
Curcumin supplementation → Fasting insulin levels
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Trackergut microbiota composition
Curcumin supplementation → gut microbiota composition
Curcumin supplementation → gut microbiota composition
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- 78
- Strong
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Supporting studies: Based on 3 studies
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
Build your evidence library
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Evidence Suggest
- Curcumin reduced HbA1c levels by 0.25% (p=0.044).
- No significant changes in blood glucose or serum insulin levels were found.
- BMI and lipid profiles remained stable throughout the study.
Who this applies to
- Older adults aged 60 and above.
- Individuals diagnosed with prediabetes.
Keep in Mind
- Results may not apply to younger populations or those without prediabetes.
- Further research is needed to confirm long-term benefits of curcumin.
- The study focused primarily on HbA1c, with other outcomes showing no significant changes.
Between the Lines
- The study did not measure long-term effects beyond the intervention period.
- Sample size and demographic diversity may limit generalizability.
- No significant changes were observed in several metabolic parameters.
Evidence Library
Build your evidence library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Curcumin Supplements and HbA1c, Curcumin Supplements and Fasting Glucose.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Curcumin Supplements → HbA1c
Supplements
Evidence Intelligence™
- EvidenceScore™
- 78
- Strong
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Supporting studies: Based on 3 studies
View evidenceSupplements
Curcumin Supplements → Fasting Glucose
Supplements
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceSupplements
Curcumin Supplements → lipid profiles
Supplements
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Curcumin Supplements Evidence Hub
All studies on Curcumin Supplements
3 studies
intervention_hubContributes to Curcumin Supplements evidence base.
HbA1c Evidence Hub
All studies measuring HbA1c
3 studies
outcome_hubMeasures HbA1c as a key outcome.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
1 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
lipid profiles Evidence Hub
All studies measuring lipid profiles
1 studies
outcome_hubMeasures lipid profiles as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Curcumin supplementation and HbA1c
Intervention: Curcumin supplementationOutcome: HbA1c
3 results
All studies on Curcumin supplementation and Blood glucose
Intervention: Curcumin supplementationOutcome: Blood glucose
1 results
All studies on Curcumin supplementation
Intervention: Curcumin supplementation
3 results
All studies measuring HbA1c
Outcome: HbA1c
3 results
All studies measuring Blood glucose
Outcome: Blood glucose
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Curcumin Supplements lower HbA1c?
Strong Evidence
Curcumin Supplements may lower HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 78.5 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 5 supporting studies with generally consistent results and a positive effect signal.
Does Curcumin Supplements improve fasting glucose?
Strong Evidence
Curcumin Supplements may improve fasting glucose.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Blood glucose
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 5 supporting studies with consistent results and a positive effect signal.
Does Curcumin Supplements affect body mass index?
Strong Evidence
Curcumin Supplements may affect body mass index.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
BMI
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Does Curcumin Supplements improve insulin resistance?
Strong Evidence
Curcumin Supplements may improve insulin resistance.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Fasting insulin levels
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Next steps
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