Research Summary
Analyzed using Evidence Intelligence™

Portfolio Diet Improves Glycemic Control in Type 2 Diabetes

Last updated September 2, 2026

Key finding

Change in HbA1c was significantly associated with a change in c-PDS (β: -0.04% per point, 95% CI: -0.07, -0.02, p = 0.001).

The Portfolio Diet was studied for its effects on glycemic control in adults with Type 2 diabetes, showing significant improvements in HbA1c levels.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

The Portfolio Diet was studied for its effects on glycemic control in adults with Type 2 diabetes, showing significant improvements in HbA1c levels.

Clinical relevance

Improving glycemic control is crucial for managing Type 2 diabetes and reducing the risk of complications. The Portfolio Diet offers a dietary strategy that can help patients achieve better blood sugar levels and improve overall cardiovascular health, making it a valuable option for dietary management in this population.

Keep in mind

The study did not assess long-term adherence to the Portfolio Diet. Results may not be generalizable to all populations with Type 2 diabetes. No significant changes in blood pressure were observed, limiting cardiovascular implications.

Published in

Journal Reference

Publication details and source links for this paper.

Meaghan EK, Songhee B, Victoria C, et al. The Portfolio Diet Improves Glycemic Control in Adults with Type 2 Diabetes: A Pooled Analysis of Randomized Trials. Nutrients. 2024;16(17):2817. doi:10.3390/nu16172817

Main Effects

HbA1c levels decreased significantly (β: -0.04%, p = 0.001).

Greater adherence to the Portfolio Diet was associated with lower LDL-C.

Lower non-HDL-C levels were observed with greater adherence to the diet.

Total cholesterol and triglycerides also decreased with adherence to the Portfolio Diet.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Portfolio Diet and Change in non-HDL cholesterol levels, Diastolic blood pressure, HbA1c, and 4 more.

Primary intervention

Portfolio Diet

Primary outcomes

  • Change in non-HDL cholesterol levels
  • Diastolic blood pressure
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

7

Evidence pairs

743

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Primary evidence

Evidence topic

Blood Pressure

matched_outcome

Related evidence

Evidence topic

HbA1c Reduction

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Change in non-HDL cholesterol levels

Portfolio Diet → Change in non-HDL cholesterol levels

Portfolio Diet → Change in non-HDL cholesterol levels

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Diastolic blood pressure

Portfolio Diet → Diastolic blood pressure

Portfolio Diet → Diastolic blood pressure

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Portfolio Diet → HbA1c

Portfolio Diet → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

LDL cholesterol

Portfolio Diet → LDL cholesterol

Portfolio Diet → LDL cholesterol

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Systolic blood pressure

Portfolio Diet → Systolic blood pressure

Portfolio Diet → Systolic blood pressure

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Total cholesterol

Portfolio Diet → Total cholesterol

Portfolio Diet → Total cholesterol

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Triglycerides

Portfolio Diet → Triglycerides

Portfolio Diet → Triglycerides

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

Build your evidence library

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evidence suggest

Evidence Suggest

  • HbA1c decreased by -0.04% per point with adherence to the diet.
  • Lower LDL-C and non-HDL-C levels were associated with the Portfolio Diet.
  • Total cholesterol and triglycerides also showed reductions.
who this applies

Who this applies to

  • Adults diagnosed with Type 2 diabetes.
  • Individuals seeking dietary interventions for glycemic control.
keep in mind

Keep in Mind

  • The study focused on short-term outcomes, so long-term effects are unknown.
  • Results may not apply to individuals outside the study's demographic.
  • Further research is needed to explore the diet's impact on blood pressure.
between the lines

Between the Lines

  • The study did not assess long-term adherence to the Portfolio Diet.
  • Results may not be generalizable to all populations with Type 2 diabetes.
  • No significant changes in blood pressure were observed, limiting cardiovascular implications.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Portfolio Diet and Blood Pressure, Portfolio Diet and HbA1c.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Diet and Nutrition

Portfolio Diet → HbA1c

Diet and Nutrition

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
View evidence

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Portfolio Diet improve change in non-hdl cholesterol levels?

Emerging Evidence

Portfolio Diet appears to improve change in non-hdl cholesterol levels.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Change in non-HDL cholesterol levels

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Portfolio Diet lower HbA1c?

Emerging Evidence

Portfolio Diet appears to lower HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Portfolio Diet improve ldl cholesterol?

Emerging Evidence

Portfolio Diet appears to improve ldl cholesterol.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    LDL cholesterol

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Portfolio Diet improve diastolic blood pressure?

Emerging Evidence

Current evidence does not show a clear benefit of Portfolio Diet for diastolic blood pressure.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Diastolic blood pressure

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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