Last updated July 12, 2026
Key finding
HbA1c decreased by -0.44 (-0.66 to -0.22)
This study investigated the effects of probiotic supplementation on glycemic control in adults with type 2 diabetes. Results showed no statistically significant improvements in key glycemic markers.
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EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Low Risk
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of probiotic supplementation on glycemic control in adults with type 2 diabetes. Results showed no statistically significant improvements in key glycemic markers.
Understanding the potential role of probiotics in managing diabetes is important for developing effective dietary interventions. However, this study indicates that probiotic supplementation alone may not be sufficient to improve glycemic control in adults with type 2 diabetes, highlighting the need for comprehensive treatment strategies that include lifestyle changes and medication.
No statistically significant changes in primary outcomes. Small sample size may limit generalizability. Short duration of the intervention may not capture long-term effects.
Published in
Publication details and source links for this paper.
Xuchao P, Hong X, Ning G, et al. Probiotic Supplementation and Glycemic Control in Adults with Type 2 Diabetes: A Randomized Controlled Trial. Frontiers in Endocrinology. 2024;15:1440286. doi:10.3389/fendo.2024.1440286
HbA1c decreased by -0.44% in the probiotic group, but not statistically significant (P>0.05).
Fasting blood glucose decreased by -0.97 mmol/L in the probiotic group, but not statistically significant (P>0.05).
Body weight decreased by -3.43 kg in the probiotic group, but not statistically significant (P>0.05).
Evidence network
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This study contributes evidence to Probiotic beverage containing Lactobacillus and Body weight, Fasting blood sugar (FBS), Fasting insulin levels, and 4 more.
This study contributes evidence to
Primary intervention
Probiotic beverage containing Lactobacillus
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
3
Related topics
7
Evidence pairs
483
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Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
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Core evidence
The primary outcomes reported in this study.
Probiotic beverage containing Lactobacillus → Body weight
Probiotic beverage containing Lactobacillus → Body weight
Probiotic beverage containing Lactobacillus → Fasting blood sugar (FBS)
Probiotic beverage containing Lactobacillus → Fasting blood sugar (FBS)
Probiotic beverage containing Lactobacillus → Fasting insulin levels
Probiotic beverage containing Lactobacillus → Fasting insulin levels
Probiotic beverage containing Lactobacillus → HbA1c
Probiotic beverage containing Lactobacillus → HbA1c
Probiotic beverage containing Lactobacillus → Insulin resistance
Probiotic beverage containing Lactobacillus → Insulin resistance
Probiotic beverage containing Lactobacillus → Total cholesterol
Probiotic beverage containing Lactobacillus → Total cholesterol
Probiotic beverage containing Lactobacillus → Triglycerides
Probiotic beverage containing Lactobacillus → Triglycerides
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Probiotic beverage containing Lactobacillus and Body Weight, Probiotic beverage containing Lactobacillus and Fasting Glucose.
This study contributes to the evidence on the following intervention-outcome relationships.
Curated evidence collections and hubs this study is part of.
All studies measuring Adipokine and Angiogenic Markers
Measures Adipokine and Angiogenic Markers as a key outcome.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies on Probiotic beverage containing Lactobacillus
Contributes to Probiotic beverage containing Lactobacillus evidence base.
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Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for Body weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for Fasting blood sugar (FBS).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting blood sugar (FBS)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for Fasting insulin levels.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting insulin levels
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of Probiotic beverage containing Lactobacillus for HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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