Supporting evidence

Low-carbohydrate diet × HbA1c

Authoritative support
19
Available studies
19
Unavailable support
0

Available supporting studies

Study 1 · Included

Almond-Based Diet Improves Depression and Glycometabolism in Type 2 Diabetes

Rct

Comparison
Participants consumed 56 g/day of almonds replacing 150 g/day of staple food, following a specific dietary regimen. · Participants followed a low fat diet education program based on a six point formula.
Duration / follow-up
13 weeks

Relevant effects

Mean difference

0.82 · 0.001

Mean difference

0 · 0.45

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Study 2 · Included

Carbohydrate-Reduced Diet Improves Glycemic Control in Type 2 Diabetes

Rct

Comparison
Participants followed a hypocaloric, carbohydrate reduced high protein diet. · Participants followed a hypocaloric conventional diabetes diet.
Duration / follow-up
30 weeks

Relevant effects

Absolute change

0

Absolute change

0

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Study 3 · Included

Carbohydrate restriction and exercise improve weight loss in prediabetes

Rct

Comparison
Participants assigned to a calorie restricted reduced carbohydrate diet. · Participants assigned to a high carbohydrate diet. · Nonresponders assigned to time restricted eating. · Nonresponders assigned to exercise counseling.
Duration / follow-up
16 weeks
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Study 4 · Included

Carbohydrate restriction improves diabetes control.

Rct

Comparison
Participants received a carbohydrate reduced high protein diet aiming for ~6% weight loss over 6 weeks. · Participants received a conventional diabetes diet for 6 weeks.
Duration / follow-up
6 weeks

Relevant effects

Mean difference

1.9 · 0.018

Absolute change

1.9 · 0.018

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Study 5 · Included

Carbohydrate restriction lowers HbA1c but not β-cell function in T2D

Rct

Comparison
Participants received a carbohydrate reduced high protein diet consisting of 30% energy from carbohydrates, 30% from proteins, and 40% from fats. · Participants received an isocaloric conventional diabetes diet consisting of 50% energy from carbohydrates, 17% from proteins, and 33% from fats.
Duration / follow-up
6 weeks

Relevant effect

Mean difference

1.9 · 0.01

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Study 6 · Included

Dietary interventions improve glycemic control in pre-diabetic patients

Rct

Comparison
Participants followed a diet where they consumed normal calories for 5 days and restricted to 500 600 kcal for 2 non consecutive days. · A plant based diet with a macronutrient distribution of 40% carbohydrates, 20% protein, and 40% fat. · Daily calorie intake restricted to 75% of total calorie intake with anti inflammatory recommendations. · Participants followed a healthy diet with a daily calorie restriction of 75% of daily energy requirements.
Duration / follow-up
17 weeks

Relevant effect

Absolute change

0.27 · 0.028

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Study 7 · Included

Higher BMI may improve glycemic response in diabetes interventions

Rct

Comparison
Intervention focused on glycemic control and weight management for overweight Veterans with type 2 diabetes. · Standard care intervention for diabetes management.
Duration / follow-up
4 weeks
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Study 8 · Included

Low-carb diet improves glycaemic control in type 1 diabetes

Rct

Comparison
Participants followed a low carbohydrate diet with 50 80g of carbohydrates per day. · Participants followed a Mediterranean diet rich in vegetables and low in red meat.
Duration / follow-up
12 weeks

Relevant effects

Absolute change

0.7 · 0.02

Absolute change

0.1 · 0.02

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Study 9 · Limited

Low-Carbohydrate Diet Improves Glycemic Control in Adolescents with Type 1 Diabetes

Rct

Comparison
Adolescents with type 1 diabetes mellitus receiving a personalized low carbohydrate diet.
Duration / follow-up
26 weeks
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Study 10 · Included

Low-Carbohydrate Diet Improves Glycemic Control in Older Adults

Rct

Comparison
Patients received a daily carbohydrate intake limited to less than 90 g without a restriction of total energy. · Patients followed a traditional diabetic diet with calorie intake stratified by individual BMI.
Duration / follow-up
104 weeks

Relevant effects

Absolute change

1.55 · 0.097

Absolute change

1.55 · 0.097

Absolute change

1.55 · 0.097

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Study 11 · Limited

Low-Carbohydrate Diet May Help Weight Loss in Pre-Diabetes

Rct

Duration / follow-up
52 weeks

Relevant effect

Mean difference

0.1

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Study 12 · Limited

Low-carbohydrate diets may improve diabetes control in type 1 diabetes

Case control

Comparison
A patient with type 1 diabetes adopted a very low carbohydrate diet and completely avoided insulin therapy for 18 months.
Duration / follow-up
338 weeks

Relevant effect

Absolute change

63

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Study 13 · Included

Moderate Carbohydrate Diet Improves Glycemic Control in Type 1 Diabetes

Rct

Comparison
Participants followed a moderate carbohydrate diet for 4 weeks. · Participants followed a traditional diabetes diet for 4 weeks.
Duration / follow-up
16 weeks
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Study 14 · Included

Moderate low-carb diet improves diabetes control.

Rct

Comparison
Patients received a daily carbohydrate intake limited to less than 90 g without any restriction to the total energy. · Patients followed a traditional diabetic diet with a target total calorie intake calculated based on ideal weight.
Duration / follow-up
78 weeks

Relevant effect

Absolute change

1.6

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Study 15 · Included

One-Meal Low-Carbohydrate Diet May Improve Metabolic Status in Type 2 Diabetes

Rct

Comparison
Patients received nutritional counseling and were instructed to restrict carbohydrate intake at dinner. · Patients followed an energy controlled diet without carbohydrate restriction at dinner.
Duration / follow-up
12 weeks
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Study 16 · Included

Online education improves glycemic control in type 2 diabetes management

Rct

Comparison
Participants received nutritional education strategies based on a low carbohydrate dietary approach delivered remotely. · Participants received conventional management for T2DM.
Duration / follow-up
16 weeks

Relevant effect

Mean difference

0.91 · 0.001

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Study 17 · Included

Very low carbohydrate diet improves glycemic control in diabetic kidney disease

Rct

Comparison
Patients received a dietary intervention of less than 20g of carbohydrate daily, supplemented by dietary consultations. · Patients received standard dietary advice of low protein diet (0.8g/kg/day) and low salt diet.
Duration / follow-up
2964 weeks

Relevant effect

Absolute change

1.3 · 0.001

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Study 18 · Included

Very low-carbohydrate diet improves glycemic control in type 2 diabetes.

Rct

Comparison
Participants followed a very low carbohydrate ketogenic diet, aiming for a blood ketone level of 0.5 to 3 mmol. · Participants followed a moderate carbohydrate, calorie restricted, low fat diet, reducing fat consumption and caloric intake.
Duration / follow-up
52 weeks

Relevant effects

Mean difference

0.5 · 0.007

Mean difference

0.2 · 0.007

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Study 19 · Included

Weight loss improves heart rate variability in type 2 diabetes

Rct

Comparison
Participants received a carbohydrate reduced high protein diet for 6 weeks. · Participants received a conventional diabetes diet for 6 weeks.
Duration / follow-up
6 weeks

Relevant effect

Percent change

25

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