Supporting evidence
Low-carbohydrate diet × HbA1c
- Authoritative support
- 19
- Available studies
- 19
- Unavailable support
- 0
Available supporting studies
Study 1 · Included
Almond-Based Diet Improves Depression and Glycometabolism in Type 2 Diabetes
Rct
- Comparison
- Participants consumed 56 g/day of almonds replacing 150 g/day of staple food, following a specific dietary regimen. · Participants followed a low fat diet education program based on a six point formula.
- Duration / follow-up
- 13 weeks
Relevant effects
Mean difference
0.82 · 0.001
Mean difference
0 · 0.45
Study 2 · Included
Carbohydrate-Reduced Diet Improves Glycemic Control in Type 2 Diabetes
Rct
- Comparison
- Participants followed a hypocaloric, carbohydrate reduced high protein diet. · Participants followed a hypocaloric conventional diabetes diet.
- Duration / follow-up
- 30 weeks
Relevant effects
Absolute change
0
Absolute change
0
Study 3 · Included
Carbohydrate restriction and exercise improve weight loss in prediabetes
Rct
- Comparison
- Participants assigned to a calorie restricted reduced carbohydrate diet. · Participants assigned to a high carbohydrate diet. · Nonresponders assigned to time restricted eating. · Nonresponders assigned to exercise counseling.
- Duration / follow-up
- 16 weeks
Study 4 · Included
Carbohydrate restriction improves diabetes control.
Rct
- Comparison
- Participants received a carbohydrate reduced high protein diet aiming for ~6% weight loss over 6 weeks. · Participants received a conventional diabetes diet for 6 weeks.
- Duration / follow-up
- 6 weeks
Relevant effects
Mean difference
1.9 · 0.018
Absolute change
1.9 · 0.018
Study 5 · Included
Carbohydrate restriction lowers HbA1c but not β-cell function in T2D
Rct
- Comparison
- Participants received a carbohydrate reduced high protein diet consisting of 30% energy from carbohydrates, 30% from proteins, and 40% from fats. · Participants received an isocaloric conventional diabetes diet consisting of 50% energy from carbohydrates, 17% from proteins, and 33% from fats.
- Duration / follow-up
- 6 weeks
Relevant effect
Mean difference
1.9 · 0.01
Study 6 · Included
Dietary interventions improve glycemic control in pre-diabetic patients
Rct
- Comparison
- Participants followed a diet where they consumed normal calories for 5 days and restricted to 500 600 kcal for 2 non consecutive days. · A plant based diet with a macronutrient distribution of 40% carbohydrates, 20% protein, and 40% fat. · Daily calorie intake restricted to 75% of total calorie intake with anti inflammatory recommendations. · Participants followed a healthy diet with a daily calorie restriction of 75% of daily energy requirements.
- Duration / follow-up
- 17 weeks
Relevant effect
Absolute change
0.27 · 0.028
Study 7 · Included
Higher BMI may improve glycemic response in diabetes interventions
Rct
- Comparison
- Intervention focused on glycemic control and weight management for overweight Veterans with type 2 diabetes. · Standard care intervention for diabetes management.
- Duration / follow-up
- 4 weeks
Study 8 · Included
Low-carb diet improves glycaemic control in type 1 diabetes
Rct
- Comparison
- Participants followed a low carbohydrate diet with 50 80g of carbohydrates per day. · Participants followed a Mediterranean diet rich in vegetables and low in red meat.
- Duration / follow-up
- 12 weeks
Relevant effects
Absolute change
0.7 · 0.02
Absolute change
0.1 · 0.02
Study 9 · Limited
Low-Carbohydrate Diet Improves Glycemic Control in Adolescents with Type 1 Diabetes
Rct
- Comparison
- Adolescents with type 1 diabetes mellitus receiving a personalized low carbohydrate diet.
- Duration / follow-up
- 26 weeks
Study 10 · Included
Low-Carbohydrate Diet Improves Glycemic Control in Older Adults
Rct
- Comparison
- Patients received a daily carbohydrate intake limited to less than 90 g without a restriction of total energy. · Patients followed a traditional diabetic diet with calorie intake stratified by individual BMI.
- Duration / follow-up
- 104 weeks
Relevant effects
Absolute change
1.55 · 0.097
Absolute change
1.55 · 0.097
Absolute change
1.55 · 0.097
Study 11 · Limited
Low-Carbohydrate Diet May Help Weight Loss in Pre-Diabetes
Rct
- Duration / follow-up
- 52 weeks
Relevant effect
Mean difference
0.1
Study 12 · Limited
Low-carbohydrate diets may improve diabetes control in type 1 diabetes
Case control
- Comparison
- A patient with type 1 diabetes adopted a very low carbohydrate diet and completely avoided insulin therapy for 18 months.
- Duration / follow-up
- 338 weeks
Relevant effect
Absolute change
63
Study 13 · Included
Moderate Carbohydrate Diet Improves Glycemic Control in Type 1 Diabetes
Rct
- Comparison
- Participants followed a moderate carbohydrate diet for 4 weeks. · Participants followed a traditional diabetes diet for 4 weeks.
- Duration / follow-up
- 16 weeks
Study 14 · Included
Moderate low-carb diet improves diabetes control.
Rct
- Comparison
- Patients received a daily carbohydrate intake limited to less than 90 g without any restriction to the total energy. · Patients followed a traditional diabetic diet with a target total calorie intake calculated based on ideal weight.
- Duration / follow-up
- 78 weeks
Relevant effect
Absolute change
1.6
Study 15 · Included
One-Meal Low-Carbohydrate Diet May Improve Metabolic Status in Type 2 Diabetes
Rct
- Comparison
- Patients received nutritional counseling and were instructed to restrict carbohydrate intake at dinner. · Patients followed an energy controlled diet without carbohydrate restriction at dinner.
- Duration / follow-up
- 12 weeks
Study 16 · Included
Online education improves glycemic control in type 2 diabetes management
Rct
- Comparison
- Participants received nutritional education strategies based on a low carbohydrate dietary approach delivered remotely. · Participants received conventional management for T2DM.
- Duration / follow-up
- 16 weeks
Relevant effect
Mean difference
0.91 · 0.001
Study 17 · Included
Very low carbohydrate diet improves glycemic control in diabetic kidney disease
Rct
- Comparison
- Patients received a dietary intervention of less than 20g of carbohydrate daily, supplemented by dietary consultations. · Patients received standard dietary advice of low protein diet (0.8g/kg/day) and low salt diet.
- Duration / follow-up
- 2964 weeks
Relevant effect
Absolute change
1.3 · 0.001
Study 18 · Included
Very low-carbohydrate diet improves glycemic control in type 2 diabetes.
Rct
- Comparison
- Participants followed a very low carbohydrate ketogenic diet, aiming for a blood ketone level of 0.5 to 3 mmol. · Participants followed a moderate carbohydrate, calorie restricted, low fat diet, reducing fat consumption and caloric intake.
- Duration / follow-up
- 52 weeks
Relevant effects
Mean difference
0.5 · 0.007
Mean difference
0.2 · 0.007
Study 19 · Included
Weight loss improves heart rate variability in type 2 diabetes
Rct
- Comparison
- Participants received a carbohydrate reduced high protein diet for 6 weeks. · Participants received a conventional diabetes diet for 6 weeks.
- Duration / follow-up
- 6 weeks
Relevant effect
Percent change
25
