September 2026
Added to Dediabetes Sep 9, 2026RCTs
This study evaluated the effects of ustekinumab in adolescents with recent-onset type 1 diabetes, finding significant improvements in C-peptide levels and reductions in specific T cell populations.
Outcomes
C-peptide incremental area under the curve (iAUC)Cytokine production from T-helper 2 cellsIL-17A-secreting T cells
Added to Dediabetes Sep 9, 2026RCTs
This study evaluated the feasibility and acceptability of Acceptance and Commitment Therapy (ACT) for adolescents with Type 1 Diabetes. Results indicated improvements in quality of life and reductions in diabetes distress for the ACT group.
Interventions
Acceptance and Commitment Therapy (ACT)
Outcomes
Diabetes distress scoresMindfulnessQuality of life
Added to Dediabetes Sep 9, 2026RCTs
This study investigated the link between glycemic control and bone health in adolescents with poorly controlled Type 1 Diabetes, finding no significant changes in HbA1c levels but some variations in bone mineral density.
Interventions
Control Group Usual ActivityMotivational Interviewing (tDNA-MI)
Outcomes
Bone Mineral Density z-scores at Proximal FemurBone Mineral Density z-scores at Total Body Less HeadBone mineral density (BMD)+3 more
Added to Dediabetes Sep 9, 2026RCTs
This study evaluated the impact of a family-centered empowerment model on glycemic control in adolescents with Type 1 diabetes, finding significant improvements in glycosylated hemoglobin and self-efficacy.
Interventions
Family-centered empowerment model
Outcomes
Communication improvementGeneral Self-Efficacy Scale scoresHbA1c+4 more
Added to Dediabetes Sep 9, 2026RCTs
The T1D REACHOUT study developed and piloted a mobile app aimed at reducing diabetes distress in adults with Type 1 Diabetes.
Interventions
T1D REACHOUT (REACHOUT)
Outcomes
Diabetes distress scoresPeer support utilizationUser Engagement Patterns Over Time
Added to Dediabetes Sep 9, 2026RCTs
This study evaluated the efficacy and safety of a fully closed-loop glucose control system in major abdominal surgery, finding significant improvements in glucose management compared to usual care.
Interventions
Full Closed Loop (FCL)Usual care
Outcomes
Pre-meal mean glucoseTime in hypoglycemia (<3.0 mmol/L)Time to glycemic target
Added to Dediabetes Sep 9, 2026RCTs
This study evaluated the impact of intermittently scanned continuous glucose monitoring (isCGM) on glycemic control and fear of hypoglycemia in adults with newly diagnosed type 1 diabetes.
Interventions
Continuous glucose monitoring
Outcomes
Fear of hypoglycemia (worry)Percentage of time spent below 70 mg/dLPre-meal mean glucose+1 more
Added to Dediabetes Sep 9, 2026RCTs
This study evaluated the effectiveness of Metformin as an adjunct to insulin therapy in adolescents with Type 1 Diabetes, finding significant improvements in HbA1c levels compared to placebo.
Outcomes
BMIBody weightCGM-based glycemic variability+4 more
Added to Dediabetes Sep 9, 2026RCTs
This study evaluated the impact of early postoperative basal insulin therapy on health-related quality of life after kidney transplantation, finding no significant influence on HRQOL.
Interventions
Insulin therapy
Outcomes
Health-related quality of lifeMental Component Summary (MCS) scoreQuality of life (physical component)
Added to Dediabetes Sep 9, 2026RCTs
This study investigated the effects of GABA on beta-cell regeneration in adults with long-standing type 1 diabetes, finding no significant improvements in key outcomes.
Outcomes
C-peptideCounter-regulatory hormone response to hypoglycemiaElevated liver transaminase+2 more