Weekly evidence changelog

What Changed This Week

Week of September 7-13, 2026Generated Sep 10, 2026

A weekly summary of studies, interventions, outcomes, and evidence relationships added to Dediabetes.

Changes reflect content added to Dediabetes during this week and may include studies published earlier.

114
New Studies
90
New Evidence Relationships
0
New Interventions
0
New Outcomes
81
Evidence Upgrades
9
Evidence Downgrades

Featured

Notable Changes

The most notable evidence graph changes detected in this weekly snapshot.

Notable Change

Aerobic Exercise -> Blood Pressure

0 new supporting studies0 total supporting studies
Notable Change

Aerobic Exercise -> Body Weight

0 new supporting studies0 total supporting studies
Notable Change

Aerobic Exercise -> CGM Time in Range

0 new supporting studies0 total supporting studies
Notable Change

Aerobic Exercise -> Adipokine and Angiogenic Markers

Aerobic ExerciseAdipokine and Angiogenic Markers

Aerobic Exercise · Adipokine and Angiogenic Markers

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
Notable Change

Aerobic Exercise -> C-peptide Levels

Aerobic ExerciseC-peptide Levels

Aerobic Exercise · C-peptide Levels

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
Notable Change

Aerobic Exercise -> Cardiovascular Outcomes

Aerobic ExerciseCardiovascular Outcomes

Aerobic Exercise · Cardiovascular Outcomes

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies

New relationships

New Evidence Relationships

Showing the top 10 relationships first from content added to Dediabetes during this week.

New Evidence Relationship

Aerobic Exercise -> Adipokine and Angiogenic Markers

Aerobic ExerciseAdipokine and Angiogenic Markers

Aerobic Exercise · Adipokine and Angiogenic Markers

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
New Evidence Relationship

Aerobic Exercise -> C-peptide Levels

Aerobic ExerciseC-peptide Levels

Aerobic Exercise · C-peptide Levels

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Cardiovascular Outcomes

Aerobic ExerciseCardiovascular Outcomes

Aerobic Exercise · Cardiovascular Outcomes

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
New Evidence Relationship

Aerobic Exercise -> Carotid Intima-Media Thickness

Aerobic ExerciseCarotid Intima-Media Thickness

Aerobic Exercise · Carotid Intima-Media Thickness

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Glucose Variability

Aerobic ExerciseGlucose Variability

Aerobic Exercise · Glucose Variability

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies2 total supporting studies
New Evidence Relationship

Aerobic Exercise -> Inflammatory Markers

Aerobic ExerciseInflammatory Markers

Aerobic Exercise · Inflammatory Markers

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Left Ventricular Structure

Aerobic ExerciseLeft Ventricular Structure

Aerobic Exercise · Left Ventricular Structure

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Aerobic Exercise -> Physical Activity Levels

Aerobic ExercisePhysical Activity Levels

Aerobic Exercise · Physical Activity Levels

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Alpha-glucosidase inhibitors -> Adipokine and Angiogenic Markers

Alpha-glucosidase inhibitorsAdipokine and Angiogenic Markers

Alpha-glucosidase inhibitors · Adipokine and Angiogenic Markers

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study
New Evidence Relationship

Alpha-glucosidase inhibitors -> Beta-cell Function

Alpha-glucosidase inhibitorsBeta-cell Function

Alpha-glucosidase inhibitors · Beta-cell Function

New evidence relationship introduced by the activated evidence publication delta.

0 new supporting studies1 total supporting study

Studies

New Studies Added

Studies added to the Dediabetes evidence system during this weekly snapshot.

RCTsAdded Sep 9, 2026

ACT Improves Psychological Outcomes for Adolescents with Type 1 Diabetes

This study evaluated the feasibility and acceptability of Acceptance and Commitment Therapy (ACT) for adolescents with Type 1 Diabetes. Results indicated improvements in quality of life and reductions in diabetes distress for the ACT group.

Acceptance and Commitment Therapy (ACT)Diabetes distress scoresMindfulness+1 more
RCTsAdded Sep 9, 2026

Aloe Vera Improves Diabetic Foot Ulcer Healing

This study evaluated the effectiveness of topical aloe vera extract in improving the healing of diabetic foot ulcers compared to standard care.

Topical aloe vera extractHigh improvement in BWAT scoreWound healing rate measured by reduction in ulcer size+1 more
RCTsAdded Sep 10, 2026

Atorvastatin may slow beta cell decline in type 1 diabetes

This study investigated the effects of atorvastatin on beta cell function in type 1 diabetes, finding that atorvastatin may enhance stimulated C-peptide secretion in certain subgroups.

AtorvastatinC-peptideCorrelation of baseline CRP levels with C-peptide outcome
RCTsAdded Sep 9, 2026

Automated insulin delivery reduces hypoglycemia risk

This study evaluated the impact of automated insulin delivery on hypoglycemia risk in adults with Type 1 diabetes, finding significant reductions in time below range.

Hybrid closed-loop systemInsulin pumpMean sensor glucose+4 more
RCTsAdded Sep 9, 2026

Bluetooth glucometers may reduce emergency visits in diabetes care

This study evaluated the effectiveness of Bluetooth-enabled glucometers compared to traditional glucometers in telehealth insulin titration for diabetes management, finding significant reductions in HbA1c levels.

Bluetooth-enabled glucometers (BTG)Traditional blood glucose meter (BGM)Diabetes distress scores+2 more
RCTsAdded Sep 9, 2026

Breastfeeding Rates Unchanged by Counseling in Diabetic Women

This study examined breastfeeding rates among women with pre-gestational diabetes mellitus through a randomized controlled trial. It found that confidence in breastfeeding knowledge significantly improved after face-to-face instruction.

Face-to-face instruction with a certified lactation consultantWritten information for controlsWritten information on breastfeeding+8 more
RCTsAdded Sep 10, 2026

Ceylon cinnamon extract lowers fasting blood sugar in T2DM.

The study evaluated the effects of Cinnamomum zeylanicum extract on LDL-C and fasting blood sugar in participants with T2DM, finding no significant reduction in LDL-C but a notable decrease in fasting blood sugar.

Cinnamomum zeylanicumASTAlanine Aminotransferase (ALT)+9 more
RCTsAdded Sep 9, 2026

CGM Improves Glycemic Management in Type 2 Diabetes

This study compared continuous glucose monitoring (CGM) to blood glucose monitoring (BGM) in adults with type 2 diabetes, finding significant improvements in HbA1c and time in range with CGM.

Continuous glucose monitoringHbA1cTime >250 mg/dL+2 more
RCTsAdded Sep 9, 2026

Chewing gum may improve blood sugar control in gestational diabetes

This study evaluated the effect of chewing gum on glycemic control in women with gestational diabetes mellitus. The gum-chewing group showed lower fasting and postprandial blood glucose levels compared to the control group.

Chewing Gum InterventionControl: Routine CareAPGAR Score at 1 Minute+9 more
RCTsAdded Sep 9, 2026

CMNT diet may maintain diabetes remission for three years

This study investigated the effects of a Chinese Medical Nutrition Therapy (CMNT) diet on type 2 diabetes remission, finding significant improvements in diabetes-related outcomes.

Chinese Medical Nutrition Therapy (CMNT) diet interventionAll-cause mortalityBody weight+6 more
RCTsAdded Sep 9, 2026

Community health worker intervention improves adherence in diabetes patients

This study evaluated a community health worker-led health literacy intervention aimed at improving adherence to lifestyle changes and medication in diabetes and hypertension patients in Harare, Zimbabwe.

CHW-led health literacy interventionAdherence to Mediterranean diet measured using MEDAS-14Adherence to alcohol moderation+8 more
RCTsAdded Sep 9, 2026

Depressive symptoms linked to worse metabolic profile in postpartum women

This study examined the relationship between depressive symptoms and metabolic profiles in women with prior gestational diabetes mellitus, finding significant associations with anxiety and metabolic syndrome.

Lifestyle intervention for prediabetesAnxiety level (STAI-6 scores)Depressive symptoms prevalence+3 more
RCTsAdded Sep 9, 2026

Diabetes and PCI Linked to Higher 10-Year Mortality

This study examined long-term outcomes in patients with left main coronary artery disease and diabetes undergoing PCI, revealing significant mortality differences based on diabetes treatment.

Percutaneous coronary intervention (PCI)All-cause mortalityCardiac death+5 more
RCTsAdded Sep 9, 2026

Early AID improves outcomes for youth with Type 1 diabetes

This study evaluated the early initiation of Automated Insulin Delivery (AID) in youth with Type 1 Diabetes from underresourced backgrounds. It found that AID showed potential benefits in satisfaction but did not significantly improve time in range compared to usual care.

Hybrid closed-loop systemUsual careDiabetes Distress in Caregivers+4 more
RCTsAdded Sep 9, 2026

Early meal timing improves nocturnal glucose levels.

This study investigated the impact of early meal timing on glucose levels in pregnant individuals with gestational diabetes, finding lower nocturnal glucose levels in the early eating group.

Continuous glucose monitoring2-hour plasma glucoseChange in diurnal mean glucose levels+4 more
RCTsAdded Sep 9, 2026

EB-CPG-based care improves T2DM management in Nepal

This study explored the experiences of Ayurvedic practitioners and patients with EB-CPG-based care for managing T2DM in Nepal, revealing predominantly positive experiences.

Integrated multidisciplinary diabetes and kidney care programUsual clinical practiceChallenges in usual clinical care+3 more
RCTsAdded Sep 9, 2026

Empagliflozin improves symptoms in diabetic neuropathy

The study investigated the effects of empagliflozin on glycaemic control and neuropathic symptoms in patients with type 2 diabetes and peripheral neuropathy, showing significant improvements in several key outcomes.

EmpagliflozinAmplitudeChange in Michigan Neuropathy Screening Instrument score+6 more
RCTsAdded Sep 9, 2026

Family-Based Intervention May Reduce T2DM Risk Factors in Women with GDM

This study evaluated a family-based health promotion intervention aimed at reducing T2DM risk factors among women with recent GDM. It found significant reductions in 2-hour insulin levels, triglycerides, and odds of elevated fasting plasma glucose.

Family-based health promotion interventionBMIDecreased 2-hour insulin concentration in OGTT associated with elevated plasma CMPF concentration+3 more
RCTsAdded Sep 9, 2026

FMT improves gastrointestinal symptoms in type 1 diabetes

This randomized pilot trial evaluated the effects of fecal microbiota transplantation (FMT) in patients with type 1 diabetes and gastroenteropathy, finding significant improvements in gastrointestinal symptoms.

Healthy lean-donor fecal microbiota transplantation capsulesGastrointestinal disorders incidenceIrritable Bowel Syndrome Impact Scale score+1 more
RCTsAdded Sep 9, 2026

Food Insecurity Linked to Healthy Eating in AI/AN Youth

This study examined the impact of a GDM risk reduction educational intervention on healthy eating behaviors among American Indian and Alaska Native adolescents, revealing mixed results.

GDM risk reduction educational interventionConsumption of vegetablesDays eating breakfast+4 more
RCTsAdded Sep 9, 2026

GABA shows no beta-cell regeneration in type 1 diabetes

This study investigated the effects of GABA on beta-cell regeneration in adults with long-standing type 1 diabetes, finding no significant improvements in key outcomes.

GABA 200 mgC-peptideCounter-regulatory hormone response to hypoglycemia+3 more
RCTsAdded Sep 9, 2026

Gamified CGM App Improves Glycemic Control in Children

A study evaluated a gamified continuous glucose monitor app and Dexcom G6 in children, finding significant improvements in glycemic outcomes.

Continuous glucose monitoringRemote multiprofessional educational programTime above range+1 more
RCTsAdded Sep 9, 2026

Higher TI Dosing Needed for Effective Glucose Management

This study evaluated the dosing patterns of Technosphere insulin in adults with Type 1 diabetes, finding significant increases in total daily doses over 30 weeks.

Insulin degludecPercentage of participants increasing TI dose by >4 U at week 17Percentage of participants increasing TI dose by >4 U at week 30+4 more
RCTsAdded Sep 9, 2026

Home-based intervention may help prevent diabetes in women with GDM

This feasibility study evaluated a home-based lifestyle modification intervention for women with gestational diabetes mellitus. The results showed unclear effectiveness in key health outcomes.

Lifestyle intervention for prediabetesBody Mass Index (BMI) changeExperience with text message reminders+8 more
RCTsAdded Sep 9, 2026

IGF-1 Linked to Bone Health in Type 1 Diabetes

This study investigated the link between glycemic control and bone health in adolescents with poorly controlled Type 1 Diabetes, finding no significant changes in HbA1c levels but some variations in bone mineral density.

Control Group Usual ActivityMotivational Interviewing (tDNA-MI)Bone Mineral Density z-scores at Proximal Femur+5 more
RCTsAdded Sep 9, 2026

IMB Intervention Improves Outcomes in Gestational Diabetes

This study evaluated the effectiveness of an Information-Motivation-Behavioral Skills (IMB) model-based nursing intervention for gestational diabetes. The IMB intervention significantly improved several health outcomes compared to traditional health education.

Lifestyle intervention for prediabetesEmergency cesarean section rateFasting Plasma Glucose (FPG)+4 more
RCTsAdded Sep 9, 2026

Innovative health education improves outcomes for gestational diabetes

This study evaluated the integration of King's Theory of Goal Attainment with FMEA-PDCA in health education for gestational diabetes, finding significant improvements in fasting plasma glucose and anxiety levels.

Conventional health education groupCotransplantation of adipose tissue-derived insulin-secreting mesenchymal stem cells and hematopoietic stem cellsAnxiety+5 more
RCTsAdded Sep 9, 2026

Intranasal Naloxone May Preserve Hypoglycemia Responses in T1D

This study investigated the pharmacokinetics of intranasal naloxone in adults with Type 1 diabetes during exercise, revealing variable plasma concentrations without significant hypoglycemic response correlations.

Intranasal naloxoneSaline (placebo)Counter-regulatory hormone response to hypoglycemia+2 more
RCTsAdded Sep 9, 2026

isCGM plus DSME improves time in range for adults with type 2 diabetes.

This post hoc analysis of the IMMEDIATE study evaluated the impact of intermittent subcutaneous continuous glucose monitoring (isCGM) combined with diabetes self-management education (DSME) on time in range (TIR) for participants with type 2 diabetes (T2D) aged under and over 65 years.

DSMESGlucose Measurement Satisfaction Survey scoreHbA1c+1 more
RCTsAdded Sep 9, 2026

isCGM use may decrease mean glucose in newly diagnosed T1DM adults

This study evaluated the impact of intermittently scanned continuous glucose monitoring (isCGM) on glycemic control and fear of hypoglycemia in adults with newly diagnosed type 1 diabetes.

Continuous glucose monitoringFear of hypoglycemia (worry)Percentage of time spent below 70 mg/dL+2 more
RCTsAdded Sep 9, 2026

Lifestyle interventions reduce gestational diabetes risk in high-risk pregnant women

This study evaluated the impact of lifestyle interventions on pregnancy outcomes in women at high risk for gestational diabetes mellitus. It found significant reductions in the risks of gestational diabetes and pregnancy-induced hypertension.

Lifestyle intervention for prediabetesEmergency cesarean section rateGestational diabetes mellitus incidence+3 more
RCTsAdded Sep 9, 2026

Low-GI Diet Improves Glycemic Control in High-Risk Adults

This study identified differential glycemic responders among adults at elevated risk of Type 2 diabetes through a randomized controlled trial comparing high and low-glycemic index diets.

High-Glycemic Index DietLow glycemic index treatment (LGIT)Blood glucose+3 more
RCTsAdded Sep 9, 2026

Mobile-based intervention may reduce metabolic syndrome risk in postpartum women

This study evaluated the efficacy of a blended mobile-based lifestyle intervention for women with glucose intolerance following gestational diabetes mellitus. The intervention showed promising results in achieving weight goals and reducing metabolic syndrome incidence.

Lifestyle intervention for prediabetesFrequency of glucose intoleranceIncidence of Metabolic Syndrome at 3 Years Postpartum+4 more
RCTsAdded Sep 9, 2026

Myo-Inositol Reduces Gestational Diabetes Risk

This study investigated the effect of Myo-Inositol on preventing gestational diabetes mellitus (GDM) and found a significant reduction in GDM incidence.

Myo-inositol plus folic acidPlacebo plus folic acidGestational diabetes mellitus incidence+5 more
RCTsAdded Sep 10, 2026

Omega-3 supplementation improves glycemic control in type 2 diabetes

This study investigated the effects of omega-3 fatty acids coadministered with glimepiride on glycemic control in patients with type 2 diabetes mellitus (T2DM). It found significant reductions in fasting plasma glucose and glycated hemoglobin levels.

1 g omega-3 fatty acids dailyPlacebo with glimepirideAtherogenic Index of Plasma Increase+8 more
RCTsAdded Sep 9, 2026

One-step method increases gestational diabetes prevalence.

This study compared the one-step and two-step methods for diagnosing gestational diabetes mellitus (GDM) and found that the one-step method significantly increased GDM prevalence.

One-step method (75-gm 2-h OGTT)Two-step method (50-gm GCT followed by 100-gm OGTT)Incidence of macrosomia+3 more
RCTsAdded Sep 9, 2026

One-step OGTT may increase GDM diagnosis without improving outcomes

This study compared two strategies for screening gestational diabetes: a two-step oral glucose tolerance test (OGTT) and a one-step OGTT. The one-step approach showed a numerically higher prevalence of gestational diabetes, but the difference was not statistically significant.

One-step method (75-gm 2-h OGTT)Two-step method (50-gm GCT followed by 100-gm OGTT)Caesarean section rate+6 more
RCTsAdded Sep 9, 2026

Pilates improves nutritional status and quality of life in older adults with diabetes

This study evaluated the impact of a 12-week Pilates intervention on nutritional status and health-related quality of life in older adults with Type 2 diabetes, finding significant improvements in various health metrics.

Pilates-based exercise programChange in Bodily Pain Domain of Health-Related Quality of LifeChange in role physical domain of health-related quality of life+6 more
RCTsAdded Sep 9, 2026

Probiotics Improve Metabolic Outcomes in Post-GDM Women

This study investigated the effects of probiotics on metabolic outcomes in women with a history of gestational diabetes, finding significant improvements in fasting plasma glucose and other metabolic markers.

ProbioticsC-reactive proteinFasting Plasma Glucose (FPG)+4 more
RCTsAdded Sep 9, 2026

Real-Time CGM Improves Glycemic Control in Type 2 Diabetes

This study evaluated the effectiveness of real-time continuous glucose monitoring (rtCGM) compared to self-monitoring of blood glucose (SMBG) in adults with insulin-requiring type 2 diabetes, finding significant improvements in glucose control with rtCGM.

Continuous glucose monitoringExtended hyperglycaemic event rate/week >13.9 mmol/LGlucose management indicator (GMI)+8 more
RCTsAdded Sep 9, 2026

Real-time glucose monitoring improves engagement in type 2 diabetes management

This study explored the experiences of individuals with Type 2 Diabetes using real-time continuous glucose monitoring (rtCGM) while on insulin. Participants reported significant improvements in glycaemia and overall well-being.

Continuous glucose monitoringBarriers to continual usage of rtCGM technologyImproved adherence to medication+4 more
RCTsAdded Sep 9, 2026

RT-CGM Enhances Glycemic Control in Prediabetes

This study evaluated the impact of real-time continuous glucose monitoring (RT-CGM) on glycemic control in prediabetes. The RT-CGM group showed significant improvements in HbA1c compared to controls.

Continuous glucose monitoringBMIFasting Plasma Glucose (FPG)+3 more
RCTsAdded Sep 9, 2026

Self-management model improves outcomes for pregnant women with diabetes

This study evaluated the effects of a self-management-clustered pregnancy care model on pregnant women with gestational diabetes mellitus, finding significant improvements in self-management abilities and health outcomes.

Self-management-cluster-based pregnancy care model (SMB-CPCM)Anxiety scale scoresDepression self-assessment scale scores+7 more
RCTsAdded Sep 9, 2026

Self-transcendence nursing improves outcomes in GDM patients

This study evaluated the self-transcendence nursing model's effectiveness in managing gestational diabetes mellitus (GDM) patients compared to routine nursing care.

Self-transcendence nursing modelDiabetes Distress Scale scoreDiabetes self-management behaviors+6 more
RCTsAdded Sep 9, 2026

Social support improves gestational diabetes management

This study explored the role of social support in managing gestational diabetes mellitus (GDM) through postpartum patient navigation. Findings indicated various forms of support and barriers faced by individuals.

Postpartum patient navigation for individuals with GDMBarriers of social supportCommunity support for diabetes management+2 more
RCTsAdded Sep 9, 2026

Sotagliflozin improves kidney function in type 1 diabetes

The study investigated the effects of sotagliflozin on copeptin levels and kidney injury in participants with type 1 diabetes, finding significant increases in copeptin and reductions in kidney injury markers.

SotagliflozinCopeptinFractional Excretion of Glucose (FE Glucose)+6 more
RCTsAdded Sep 9, 2026

Tailored diabetes education improves self-efficacy in Chinese Americans

A pilot randomized controlled trial found that a culturally tailored diabetes education program improved self-efficacy and dietary adherence among Chinese Americans with Type 2 diabetes.

Stepped care diabetes prevention program with financial incentivesAdherence to a healthy dietDiabetes distress scores+1 more
RCTsAdded Sep 9, 2026

Telephone support for lifestyle changes shows no reduction in diabetes incidence

This study evaluated a postpartum telephone-based lifestyle intervention for women at high risk of diabetes after gestational diabetes mellitus. The findings indicated no significant reduction in diabetes incidence or weight gain.

Normal carePostpartum telephone support for lifestyle changesDiscrepancy between clinically measured weight and self-reported weight associated with BMI+1 more
RCTsAdded Sep 9, 2026

Ustekinumab improves beta-cell function in type 1 diabetes

This study evaluated the effects of ustekinumab in adolescents with recent-onset type 1 diabetes, finding significant improvements in C-peptide levels and reductions in specific T cell populations.

UstekinumabC-peptide incremental area under the curve (iAUC)Cytokine production from T-helper 2 cells+1 more
RCTsAdded Sep 9, 2026

Video Intervention Improves Medication Adherence in Older Adults with Diabetes

The study evaluated the impact of the 'Diabetes Little Helper' video intervention on medication adherence among older adults with Type 2 diabetes, finding significant improvements in various adherence-related scores.

Diabetes Little Helper video interventionAttitude score measured before and after interventionDiabetes social support+4 more

Entities

New Interventions & Outcomes

New intervention and outcome entities created during this weekly snapshot.

No new intervention or outcome entities were added this week.

EvidenceScore™

EvidenceScore™ Changes

Evidence Upgrade

Aerobic Exercise -> Blood Pressure

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Body Weight

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> CGM Time in Range

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Fasting Glucose

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Quality of Life Outcomes

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Aerobic Exercise -> Sleep Outcomes

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Alpha-glucosidase inhibitors -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Alpha-glucosidase inhibitors -> Postprandial and OGTT Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Adipokine and Angiogenic Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Body Mass Index

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Fasting Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Bariatric Procedures -> Insulin Resistance

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Adipokine and Angiogenic Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Body Mass Index

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Inflammatory Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Insulin Resistance

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Curcumin Supplements -> Oxidative Stress Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Adipokine and Angiogenic Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Fasting Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Insulin Resistance

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Digital Lifestyle Interventions -> Mental Health

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

DPP-4 Inhibitors -> Body Composition

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

DPP-4 Inhibitors -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Blood Pressure

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Body Weight

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Diabetes Incidence and Prevention

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Hypoglycemia

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Mental Health

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Adipokine and Angiogenic Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Body Mass Index

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Body Weight

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Fasting Glucose

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Glucose Variability

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Hypoglycemia

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Delivery Systems -> Postprandial and OGTT Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Therapies -> Kidney Function

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Insulin Therapies -> Treatment Experience

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Adipokine and Angiogenic Markers

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Blood Pressure

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Body Mass Index

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Body Composition

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Body Weight

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Fasting Glucose

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Ketogenic Diets -> Quality of Life Outcomes

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Blood Pressure

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Body Mass Index

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Body Weight

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> CGM Time in Range

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Fasting Glucose

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Glucose Variability

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> HbA1c

Strong -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Insulin Resistance

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Mental Health

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Physical Activity Levels

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Low-Carbohydrate Diet Education -> Postprandial and OGTT Glucose

Emerging -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Metformin Therapies -> Adipokine and Angiogenic Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Metformin Therapies -> Blood Pressure

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Metformin Therapies -> Body Composition

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Diabetes Management Self-Efficacy

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Mental Health

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Postprandial and OGTT Glucose

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

mHealth Diabetes Support Interventions -> Quality of Life Outcomes

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Mind-Body and Balance Exercise -> Fasting Glucose

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Mind-Body and Balance Exercise -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Probiotics and Synbiotics -> Oxidative Stress Markers

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Blood Pressure

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Body Mass Index

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Body Composition

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> CGM Time in Range

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Glucose Variability

Emerging -> Emerging

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Insulin Resistance

Moderate -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

SGLT2 Inhibitors -> Quality of Life Outcomes

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Sulfonylureas -> Fasting Glucose

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Telehealth Interventions -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Thiazolidinediones -> Adipokine and Angiogenic Markers

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Thiazolidinediones -> HbA1c

Moderate -> Strong

EvidenceScore increased in the activated evidence publication delta.

Evidence Upgrade

Thiazolidinediones -> Insulin Resistance

Emerging -> Moderate

EvidenceScore increased in the activated evidence publication delta.

Evidence Downgrade

Diabetes Self-Management Education and Support (DSMES) Programs -> Kidney Function

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

GLP-1 Receptor Agonists -> Retinopathy

Emerging -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Metformin Therapies -> Hypoglycemia

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Probiotics and Synbiotics -> Body Composition

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Probiotics and Synbiotics -> Insulin Resistance

Strong -> Strong

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Probiotics and Synbiotics -> Kidney Function

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

SGLT2 Inhibitors -> Urinary Tract Infections

Strong -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Sulfonylureas -> Hypoglycemia

Strong -> Moderate

EvidenceScore decreased in the activated evidence publication delta.

Evidence Downgrade

Thiazolidinediones -> Body Weight

Moderate -> Emerging

EvidenceScore decreased in the activated evidence publication delta.

Evidence Updates

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